Results 101 to 110 of about 316,970 (234)

Clinical significance and immune microenvironment association of cuproptosis‐related genes in pan‐cancer

Experimental Physiology, EarlyView.
Abstract Recent studies highlight the important roles of cuproptosis in cancer cells. However, the roles of the cuproptosis‐related genes (CRGs) in different cancers are still not fully understood. Comprehensive analysis was performed using open‐source bioinformatic platforms to disclose the expression profiles, prognostic significance, genomic and ...
Xinyu Ge, Kaijing Wang, Tian Zhao, Jinyi Wang, Jie Liu, Zhengliang Sun, Zhengjun Chai, Wen Zhang, Chengbao Li, Yan Xu, Guohan Chen   +10 more
wiley   +1 more source

Targeting CD70 in cancer: Mechanisms of immune escape and translational opportunities

Clinical and Translational Discovery, Volume 5, Issue 6, December 2025.
Hypoxia, oncogenic signaling (e.g., MAPK, STAT3), and histone modifications promote CD70 overexpression in cancer cells. Viral infections like EBV and HTLV‐1 induce CD70 expression in tumor and transformed immune cells. Tyrosine kinase inhibitors and chemotherapeutic agents induce CD70 expression through therapy‐related stress in cancer cells ...
Akash Sabarwal, Saba Tabasum, Laxminarayan Rawat, Soumitro Pal   +3 more
wiley   +1 more source

A Machine Learning‐Optimized Immunogenic Cell Death Signature Reveals Tumor Immunogenicity and the Immunotherapy Response of Pancancer

MedComm – Future Medicine, Volume 4, Issue 4, December 2025.
This study introduces an innovative adversarial validation (AV) strategy integrated with machine learning to mitigate the problem of data set shift and enhance analyses of pan‐cancer immunogenicity. It identifies key immunogenic cell death‐related biomarkers and demonstrates their predictive potential for survival outcomes and responses to PD‐1 ...
Li Qiu, Danqing Huang, Yuening Zhang, Yingying Zhou, Ming Luo, Chengdong Zhang, Ying Huang, Mingyuan Zou, Wenlong Lu, Hui Liu, Shaowei Liu, Haoyang Huang, Kaiwen Ye, Yuan Hui, Cheng Tang, Zilong Yan, Xi Zhong, Zhiguo Luo, Hongxin Huang, Ming Zhou, Guangshuai Jia, Qibin Leng, Jun Liu   +22 more
wiley   +1 more source

Thyroid Cancer: Pathogenesis, Clinicopathology, Diagnosis, and Management

MedComm, Volume 6, Issue 11, November 2025.
Thyroid cancer risk is influenced by both genetic and modifiable factors, including mutations, radiation exposure, lifestyle, and pre‐existing benign conditions. Diagnosis involves physical exams, ultrasound, scintigraphy, laboratory tests, and fine‐needle aspiration biopsy (FNAB).
Yu‐Dong Li, Qing‐Yao Ye, Yan‐Xing Chen, Xia‐Rong Hu   +3 more
wiley   +1 more source

Thymoma masquerading as transfusion dependent anemia

Indian Journal of Medical and Paediatric Oncology, 2016
Pure red cell aplasia (PRCA) is a known entity in clinical medicine. Patients are often transfusion dependent for their whole life. Ascertaining its etiology is always a herculean task.
Javvid Muzamil, Aejaz Aziz Shiekh, Gull Mohammad Bhat, Abdul Rashid Lone, Shuaeb Bhat, Firdousa Nabi   +5 more
doaj   +1 more source

The effect of helper virus on Abelson virus-induced transformation of lymphoid cells [PDF]

, 1978
Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses.
Baltimore, David, Rosenberg, Naomi
core   +2 more sources

A Cross‐Sectional Study of Quality of Life and Body Image in Myasthenia Gravis Patients: A Novel Approach Using the Individualized Neuromuscular Quality of Life Questionnaire

Muscle &Nerve, Volume 72, Issue 5, Page 1091-1099, November 2025.
ABSTRACT Introduction/Aims Many generic and disease‐specific quality of life (QoL) measures have been used to understand the perspectives of patients with myasthenia gravis (MG). However, there is limited data regarding the use of the Individualized Neuromuscular Quality of Life Questionnaire (INQoL) and the impact of body image in patients with MG ...
Michael Chou, Meg Mendoza, Hans Katzberg, Vera Bril, Carolina Barnett‐Tapia   +4 more
wiley   +1 more source

Long-term prognosis in patients with thymoma combined with myasthenia gravis: a propensity score-matching analysis

Frontiers in Medicine
IntroductionWe aimed to assess the impact of myasthenia gravis (MG) on the long-term prognosis in patients with thymoma after surgery and identify related prognostic factors or predictors.MethodsThis retrospective observational study included 509 ...
Kai Zhao, Kai Zhao, Yiming Liu, Miao Jing, Wenhan Cai, Jiamei Jin, Zirui Zhu, Zirui Zhu, Leilei Shen, Leilei Shen, Jiaxin Wen, Zhiqiang Xue   +11 more
doaj   +1 more source

Characteristics of Mediastinal Tumor Patients in Cipto Mangunkusumo National Hospital Jakarta [PDF]

, 2013
Tumor mediastinum mewakili keragaman penyakit di berbagai negara. Di Indonesia, khususnya di Rumah Sakit Nasional Cipto Mangunkusumo, masih kekurangan karakteristik epidemiologi, klinis, radiologi, dan karakteristik histopatologi dari tumor mediastinal ...
Amin, Z. (Zulkifli)
core  

Comparison of the Quantitative Myasthenia Gravis and Myasthenia Gravis Activity of Daily Living Scores From a Clinical Practice Perspective

Muscle &Nerve, Volume 72, Issue 5, Page 1100-1107, November 2025.
ABSTRACT Introduction/Aims Myasthenia gravis (MG) is characterized by fluctuating symptoms, making the assessment of disease activity challenging. Discordance between the clinician‐reported quantitative myasthenia gravis (QMG) score and the patient‐reported MG activity of daily living (MG‐ADL) has previously been observed.
Wanqing Wu, Malin Petersson, Fredrik Piehl, Susanna Brauner   +3 more
wiley   +1 more source