Results 111 to 120 of about 44,586 (279)

Treatment of Neurogenic Voice Disorders

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This overview serves as a foundational resource for clinicians caring for neurologically complex patients presenting with voice complaints. Neurogenic voice disorders are diverse in their clinical presentations and therapeutic approaches. A thorough medical history, including family history, detailed laryngeal examination, voice assessments ...
Mausumi Syamal
wiley   +1 more source

Radiological Insights Into the Pericardium: A Comprehensive Review

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT The pericardium is not simply a two‐layered membrane surrounding the heart and great vessels. Pericardial effusion is the most common manifestation of various pathological conditions involving the pericardium. Therefore, we are tempted to think of the pericardium as a virtual space containing only fluid, but it can also contain solid and ...
Felipe Aluja‐Jaramillo, Omar Andrés Pantoja‐Burbano, Fernando R. Gutiérrez, Carlos Previgliano, Sanjeev Bhalla   +4 more
wiley   +1 more source

The cerebellum in epilepsy

Epilepsia, EarlyView.
Abstract The cerebellum, a subcortical structure, is traditionally linked to sensorimotor integration and coordination, although its role in cognition and affective behavior, as well as epilepsy, is increasingly recognized. Cerebellar dysfunction in patients with epilepsy can result from genetic disorders, antiseizure medications, seizures, and seizure‐
Christopher Elder, Rebecca Kerestes, Puneet Opal, Maria Marchese, Orrin Devinsky   +4 more
wiley   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Thymoma with Autoimmune Hemolytic Anemia

Case Reports in Oncology, 2014
A 38-year-old Japanese male was referred to our hospital with abnormal chest X-ray results and severe Coombs-positive hemolytic anemia. He was diagnosed with a stage IV, WHO type A thymoma and was treated with oral prednisolone (1 mg/kg/day) and ...
Kensuke Suzuki, Minehiko Inomata, Shiori Shiraishi, Ryuji Hayashi, Kazuyuki Tobe   +4 more
doaj   +1 more source

Frequency of Synaptic Autoantibody Accompaniments and Neurological Manifestations of Thymoma.

JAMA Neurology, 2016
IMPORTANCE Thymoma is commonly recognized in association with paraneoplastic autoimmune myasthenia gravis (MG), an IgG-mediated impairment of synaptic transmission targeting the nicotinic acetylcholine receptor of muscle.
A. Zekeridou, A. McKeon, V. Lennon
semanticscholar   +1 more source

Thymoma-associated T-cell immunodeficiency after radiotherapy: A case report

Respiratory Medicine Case Reports, 2021
Acquired immunodeficiency in thymoma (Good's syndrome) without hypogammaglobulinemia is a rare condition. Here we describe the case of a 29-year-old Japanese woman with thymoma-associated T cell immunodeficiency after radiation therapy.
Kensuke Nakagawara, Shotaro Chubachi, Shuhei Azekawa, Shiro Otake, Ayaka Saito, Masahiko Okada, Ko Lee, Katsunori Masaki, Naoyoshi Koike, Hirofumi Kamata, Ichiro Kawada, Shigeaki Suzuki, Makoto Ishii, Koichi Fukunaga   +13 more
doaj  

Surgical treatment of thymoma: an 11-year experience with 761 patients.

European Journal of Cardio-Thoracic Surgery, 2016
OBJECTIVES Thymomas are rare, and information regarding their surgical outcomes and possible prognostic factors is limited. In this study, we aimed to determine the clinicopathological characteristics of thymoma and estimate independent predictors of ...
Yang Zhao, Jianxin Shi, Limin Fan, D. Hu, Jun Yang, Heng Zhao   +5 more
semanticscholar   +1 more source

The G protein‐coupled receptor GPR89A is a novel potential therapeutic target to overcome cisplatin resistance in NSCLC Calu1 cells

The FEBS Journal, EarlyView.
A genome‐wide CRISPR‐Cas9‐based genetic screen in cisplatin‐resistant NSCLC cells revealed 63 potential candidate genes for overcoming cisplatin resistance, including GPR89A. GPR89A, localised in the Golgi, modulates voltage‐gated anion channel activity and is involved in intracellular pH reduction.
Hale Guler Kara, Eda Dogan, Vildan Bozok, Cagdas Aktan, Ece Cakiroglu, Zuhal Eroglu, Duygu Aygunes Jafari, Kemal Sami Korkmaz, Serif Senturk, Buket Kosova   +9 more
wiley   +1 more source

Using proteomic profiling to characterize protein signatures of different thymoma subtypes

BMC Cancer, 2019
Background Histology is a traditional way to classify subtypes of thymoma, because of low cost and convenience. Yet, due to the diverse morphology of thymoma, this method increases the complexity of histopathologic classification, and requires ...
Liang-Chuan Lai, Qiang-Ling Sun, Yu-An Chen, Yi-Wen Hsiao, Tzu-Pin Lu, Mong-Hsun Tsai, Lei Zhu, Eric Y. Chuang, Wentao Fang   +8 more
doaj   +1 more source