Results 121 to 130 of about 91,729 (314)

Clinical Application of In‐House Comprehensive Genomic Profiling for Thoracic Cancer: Insights From a Japanese Hospital

Cancer Science, EarlyView.
We clarified the utility and challenges of in‐house comprehensive genomic profiling (CGP) testing in lung cancer care. ABSTRACT Comprehensive genomic profiling (CGP) is useful for optimizing targeted therapy and immunotherapy strategies for thoracic malignancies. This study aimed to evaluate the clinical utility and diagnostic complementarity of the in‐
Hatsuyo Takaoka, Hideki Terai, Kohei Nakamura, Takaaki Mizuno, Ryutaro Kawano, Katsura Emoto, Yutaka Kurebayashi, Nao Takada, Kenta Hamabe, Kazuhito Horie, Akihiko Ogata, Katsuhito Kinoshita, Lisa Shigematsu, Fumimaro Ito, Masahiko Okada, Takahiro Fukushima, Shigenari Nukaga, Testuo Tani, Keiko Ohgino, Kaoru Kaseda, Shinnosuke Ikemura, Hiroyuki Yasuda, Keisuke Asakura, Hajime Okita, Hiroshi Nishihara, Koichi Fukunaga   +25 more
wiley   +1 more source

Pure red cell aplasia associated with thymoma: a report of a single-center experience.

Journal of Thoracic Disease, 2018
Background Pure red cell aplasia (PRCA) associated with thymoma is relatively rare, and relevant reports are limited. We investigated the clinical features and outcomes of PRCA associated with thymoma in this study.
S. Moriyama, M. Yano, H. Haneda, K. Okuda, O. Kawano, Tadashi Sakane, Risa Oda, Takuya Watanabe, R. Nakanishi   +8 more
semanticscholar   +1 more source

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Thyroid lesions of neuroendocrine origin? Thinking of a “polka‐dotted” zebra! Case series from three Italian referral centers and review of the literature

Journal of Neuroendocrinology, EarlyView.
Thyroid metastases from neuroendocrine neoplasm (NEN) should be considered in case of suspicious thyroid nodules in patients with a positive medical history of NEN, mainly of thoracic origin, even after many years from the initial diagnosis. The differential diagnosis from primary intrathyroidal NEN is challenging.
Tiziana Feola, Alessia Cozzolino, Federica Grillo, Maria Francesca Birtolo, Irene Aini, Erika Messina, Roberto Minotta, Alessia Filice, Isabella Zanata, Paola Razzore, Manila Rubino, Andrea M. Isidori, Annamaria Colao, Antongiulio Faggiano, Elisa Giannetta, on behalf of NIKE group, Irene Aini, Manuela Albertelli, Ylenia Alessi, Simone Antonini, Luigi Barrea, Elio Benevento, Maria Francesca Birtolo, Federica Campolo, Celeste Cantone, Silvia Carra, Rob‐erta Centello, Alessia Cozzolino, Federica De Cicco, Valentina Di Vito, Beatrice Fazzalari, Stefano Gay, Elisa Giannetta, Federica Grillo, Elia Guadagno, Valentina Guarnotta, Iderina Hasballa, Alice Laffi, Andrea Lania, Alessia Liccardi, Rossella Mazzilli, Erika Messina, Roberto Minotta, Giovanna Muscogiuri, Carla Pandozzi, Gabriella Pugliese, Giulia Puliani, Alberto Ragni, Manila Rubino, Rosaria Maddalena Ruggeri, Franz Sesti, Maria Grazia Tarsitano, Ludovica Verde, Giovanni Vitale, Virginia Zamponi, Isabella Zanata, Roberta Modica, Giuseppe Fanciulli, Anna La Salvia, Erika Maria Grossrubatscher, Francesco Ferrau, Alessandro Veresani, Flaminia Russo   +62 more
wiley   +1 more source

Evaluation of Decreased Kidney Function in Dogs Receiving Carboplatin: A Retrospective Cohort Study of 98 Dogs (2006–2024)

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Decreased kidney function is observed in some people receiving carboplatin, but limited literature explores this in dogs. The aim of this study was to evaluate the incidence and risk factors for decreased kidney function in dogs receiving carboplatin.
Andrew D. Yale, Alvina So, Alexandra Guillén, Isabelle Desmas‐Bazelle, Francesco Rogato, Rosanne E. Jepson   +5 more
wiley   +1 more source

Thymoma masquerading as transfusion dependent anemia

Indian Journal of Medical and Paediatric Oncology, 2016
Pure red cell aplasia (PRCA) is a known entity in clinical medicine. Patients are often transfusion dependent for their whole life. Ascertaining its etiology is always a herculean task.
Javvid Muzamil, Aejaz Aziz Shiekh, Gull Mohammad Bhat, Abdul Rashid Lone, Shuaeb Bhat, Firdousa Nabi   +5 more
doaj   +1 more source

Identification of a Candidate CD5 Homologue in the Amphibian Xenopus laevis [PDF]

, 1995
We identified a novel T cell Ag in the South African clawed toad (Xenopus laevis) by a mAb designated 2B1. This Ag is present in relatively high levels on most thymocytes, approximately 65% of splenocytes, 55% of PBL, and 65% of intestinal lymphocytes ...
Cooper, Max D., Gartland, Lanier A., Göbel, Thomas W. F., Horton, John D., Jürgens, Jutta B., Pasquier, Louis D.   +5 more
core  

State of the art: diagnostic tools and innovative therapies for treatment of advanced thymoma and thymic carcinoma.

European Journal of Cardio-Thoracic Surgery, 2016
In this review article, state-of-the-art diagnostic tools and innovative treatments of thymoma and thymic carcinoma (TC) are described with special respect to advanced tumour stages.
M. Ried, A. Marx, A. Götz, O. Hamer, B. Schalke, H. Hofmann   +5 more
semanticscholar   +1 more source

Retrospective study on Encephalitozoon cuniculi infections in 118 cat and 9 dog eyes

Veterinary Ophthalmology, EarlyView.
Abstract Purpose This study aims to inform about the clinical image, diagnostic possibilities, and treatment options for cats and dogs diagnosed with ocular encephalitozoonosis. Materials and Methods Medical records of 7 dogs and 75 cats with ocular encephalitozoonosis presented at the Clinical Unit of Ophthalmology of the University of Veterinary ...
Sophie Hofmann‐Wellenhof, Barbara Nell
wiley   +1 more source

Purulent pericarditis in advanced thymoma: A case report

Radiology Case Reports, 2022
Thymoma is the most common primary anterior mediastinum mass with various clinical manifestations, and one of the manifestations is pericardial effusion.
Jordan Bakhriansyah, MD, I Gede Parama Gandi Semita, MD, I Gde Rurus Suryawan, MD, Yusuf Azmi, MD, Irfan Deny Sanjaya, MD, Risma Ikawaty, MD, David Nugraha, BM, Firas Farisi Alkaff, MD   +7 more
doaj