Results 31 to 40 of about 305,149 (190)

Comparison of Efficacy and Safety of Platinum-Based Chemotherapy as First-Line Therapy between B3 Thymoma and Thymic Carcinoma

Current Oncology, 2022
Background: B3 type thymoma is defined as a well-differentiated thymic carcinoma and is similar to a thymic carcinoma. However, the differences between them are not well defined.
Yue Hao, Jinfei Si, Jianan Jin, Jingwen Wei, Jing Xiang, Chunwei Xu, Zhengbo Song   +6 more
doaj   +1 more source

Characterization of IL-10-producing regulatory B cells in thymoma

Autoimmunity, 2022
Background Regulatory B cells (Bregs) are a subset of B cells that secrete interleukin 10 (IL-10) and play a vital role in suppressing the immune response. The aim of this study was to evaluate the proportion of Bregs in patients with thymoma.
Fangnan Lin, Hailong You, Xiwen Cao, Tingting Li, Xiaodong Hong, Jinli Yang, Peng Huo, Jialin Li, Wei Liu, Yanfang Jiang   +9 more
doaj   +1 more source

3D DenseNet Deep Learning Based Preoperative Computed Tomography for Detecting Myasthenia Gravis in Patients With Thymoma

Frontiers in Oncology, 2021
BackgroundMyasthenia gravis (MG) is the most common paraneoplastic syndromes of thymoma and closely related to thymus abnormalities. Timely detecting of the risk of MG would benefit clinical management and treatment decision for patients with thymoma ...
Zhenguo Liu, Ying Zhu, Ying Zhu, Yujie Yuan, Lei Yang, Kefeng Wang, Minghui Wang, Xiaoyu Yang, Xi Wu, Xi Tian, Rongguo Zhang, Bingqi Shen, Honghe Luo, Huiyu Feng, Shiting Feng, Zunfu Ke, Zunfu Ke   +16 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Thymoma Profile at Dr. Moewardi General Hospital: Does Thymoma Size Really Affect Distant Metastasis?

Jurnal Respirasi
Introduction: Size is a predictor factor of a patient’s prognosis and metastasis in solid tumors. This study determined the relationship between thymoma size and distant metastasis.
Novita Silvana Thomas, Fahlevie Fahlevie, Ana Rima Setijadi, Widiastuti Widiastuti, Sastia Rakhma   +4 more
doaj   +1 more source

Paraneoplastic pemphigus regression after thymoma resection

World Journal of Surgical Oncology, 2008
Background Among human neoplasms thymomas are associated with highest frequency with paraneoplastic autoimmune diseases. Case presentation A case of a 42-year-old woman with paraneoplastic pemphigus as the first manifestation of thymoma is reported ...
Stergiou Eleni, Asteriou Christos, Boukovinas Ioannis, Paliouras Dimitrios, Samanidis Georgios, Barbetakis Nikolaos, Laschos Kostas, Tsilikas Christodoulos   +7 more
doaj   +1 more source

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer, Frauke Stascheit, Maximilian Mönch, Paolo Doksani, Carla Dusemund, Meret Herdick, Philipp Mergenthaler, Maike Stein, Amani Suboh, Jutta Schröder‐Braunstein, Guido Wabnitz, Jan D. Lünemann, Sophie Lehnerer, Sarah Hoffmann, Andreas Meisel   +14 more
wiley   +1 more source

Thymoma with acute gastric volvulus: a case report

BMC Cancer, 2017
Background Acute gastric volvulus (GV) is a rare disease with high mortality rate often associated with anatomic abnormalities. Thymoma is the most common neoplasm located in the anterior mediastinum. There is no reported relationship between thymoma and
Ailing Liu, Xin Gao, Lin Zhao
doaj   +1 more source

Fibrous bands associated with higher Masaoka stage and poor recurrence‐free survival in patients with thymoma

Thoracic Cancer, 2021
Background Fibrous bands (FBs) are one of the histological features in tumors which can be confirmed by hematoxylin and eosin (H&E)‐stained slides. FBs have been reported to correlate with malignancy in various tumors.
Kazuhiro Minami, Naoe Jimbo, Yugo Tanaka, Takahiro Uchida, Takeshi Okamoto, Nahoko Shimizu, Takefumi Doi, Daisuke Hokka, Tomoo Itoh, Yoshimasa Maniwa   +9 more
doaj   +1 more source

Intrapericardial Thymoma Presented as Pericardial Tamponade with Post-Operative Myasthenia Gravis

Medicina, 2022
Background: Thymoma is an epithelial mass arising from the thymus. Most thymomas are located in the anterior mediastinum. Ectopic intrapericardial thymoma is very unusual; to date, only eight cases of pericardial thymoma have been reported. Among thymoma
Yueh-Hsun Tsai, Kai-Hsiung Ko, Hao Yen, Tsai-Wang Huang   +3 more
doaj   +1 more source