Results 41 to 50 of about 316,970 (234)

Thymoma calcification: Is it clinically meaningful?

World Journal of Surgical Oncology, 2011
Among anterior mediastinal lesions, thymoma is the most common. Thymomas are tumors of thymic epithelial cell origin that are distinguished by inconsistent histological and biologic behavior.
Alkaied Homam, Azab Basem, Elsayegh Dany, Harris Kassem, Chalhoub Michel   +4 more
doaj   +1 more source

Characterization of IL-10-producing regulatory B cells in thymoma

Autoimmunity, 2022
Background Regulatory B cells (Bregs) are a subset of B cells that secrete interleukin 10 (IL-10) and play a vital role in suppressing the immune response. The aim of this study was to evaluate the proportion of Bregs in patients with thymoma.
Fangnan Lin, Hailong You, Xiwen Cao, Tingting Li, Xiaodong Hong, Jinli Yang, Peng Huo, Jialin Li, Wei Liu, Yanfang Jiang   +9 more
doaj   +1 more source

Comparison of Efficacy and Safety of Platinum-Based Chemotherapy as First-Line Therapy between B3 Thymoma and Thymic Carcinoma

Current Oncology, 2022
Background: B3 type thymoma is defined as a well-differentiated thymic carcinoma and is similar to a thymic carcinoma. However, the differences between them are not well defined.
Yue Hao, Jinfei Si, Jianan Jin, Jingwen Wei, Jing Xiang, Chunwei Xu, Zhengbo Song   +6 more
doaj   +1 more source

Somatostatin receptor subtypes in human thymoma and inhibition of cell proliferation by octreotide in vitro [PDF]

, 2000
Somatostatin (SS) and SS receptor (SSR) subtypes, code-named sst1-5, are heterogeneously expressed in the normal human thymus. This suggests their involvement in controlling the immune and/or neuroendocrine functions in this organ ...
Colao, A. (Annamaria), Ferone, D. (Diego), Hagen, P.M. (Martin) van, Hofland, L.J. (Leo), Koetsveld, P.M. (Peter) van, Kwekkeboom, D.J. (Dirk Jan), Lamberts, S.W.J. (Steven), Lichtenauer-Kaligis, E.G.R. (Elgin), Mooy, D.M., Schonbrunn, A.   +9 more
core   +1 more source

Transgenic expression of the Ly49A natural killer cell receptor confers class I major histocompatibility complex (MHC)-specific inhibition and prevents bone marrow allograft rejection. [PDF]

, 1996
Natural killer (NK) cells and some T cells are endowed with receptors specific for class I major histocompatibility complex (MHC) molecules that can inhibit cellular effector functions.
Cado, D, Held, W, RAULET, David H.
core   +1 more source

Thymoma-associated T-cell immunodeficiency after radiotherapy: A case report

Respiratory Medicine Case Reports, 2021
Acquired immunodeficiency in thymoma (Good's syndrome) without hypogammaglobulinemia is a rare condition. Here we describe the case of a 29-year-old Japanese woman with thymoma-associated T cell immunodeficiency after radiation therapy.
Kensuke Nakagawara, Shotaro Chubachi, Shuhei Azekawa, Shiro Otake, Ayaka Saito, Masahiko Okada, Ko Lee, Katsunori Masaki, Naoyoshi Koike, Hirofumi Kamata, Ichiro Kawada, Shigeaki Suzuki, Makoto Ishii, Koichi Fukunaga   +13 more
doaj   +1 more source

Distribution of Ectopic Germinal Centers in Thymic Epithelial Tumors and Their Relationship With Thymic Involution. [PDF]

Cancer Sci
In this study, we demonstrate that ectopic germinal centers were observed in less involuted thymus of thymic epithelial tumors positive for antiacetylcholine receptor antibodies, associating their presence with higher antibody titers and supporting the need for at least a total thymectomy in younger patients. ABSTRACT Ectopic germinal centers (GCs) are
Furuya T, Tando S, Ogi H, Shimomura M, Okada S, Ishihara S, Nakazono C, Itoh K, Inoue M.   +8 more
europepmc   +2 more sources

Unraveling the role of ectopic thymic tissue in patients undergoing thymectomy for myasthenia gravis [PDF]

, 2019
Extended thymectomy has been considered the goal of surgery for myasthenia gravis (MG) mainly due to the existence of ectopic thymic tissue. Recently, ectopic thymic tissue has attracted increasing attention in patients with MG following thymectomy ...
Bauer, Gero, Elsner, Aron, Englisch, Julianna, Ismail, Mahmoud, Li, Feng, Li, Zhongmin, Meisel, Andreas, Rückert, Jens-C., Swierzy, Marc, Tao, Ya   +9 more
core   +1 more source

3D DenseNet Deep Learning Based Preoperative Computed Tomography for Detecting Myasthenia Gravis in Patients With Thymoma

Frontiers in Oncology, 2021
BackgroundMyasthenia gravis (MG) is the most common paraneoplastic syndromes of thymoma and closely related to thymus abnormalities. Timely detecting of the risk of MG would benefit clinical management and treatment decision for patients with thymoma ...
Zhenguo Liu, Ying Zhu, Ying Zhu, Yujie Yuan, Lei Yang, Kefeng Wang, Minghui Wang, Xiaoyu Yang, Xi Wu, Xi Tian, Rongguo Zhang, Bingqi Shen, Honghe Luo, Huiyu Feng, Shiting Feng, Zunfu Ke, Zunfu Ke   +16 more
doaj   +1 more source

Diagnostic accuracy of multidetector computed tomography scan in mediastinal masses assuming histopathological findings as gold standard [PDF]

, 2018
Purpose: Aim of the study was to: 1) present MDCT characteristics of different mediastinal mass lesions, 2) estimate proportion of benign and malignant mediastinal mass lesions based on MDCT findings, and 3) find out the diagnostic accuracy with ...
Jaipal, Usha, Mannan, Nima, Pandey, Somshankar, Yadav, Rajkumar   +3 more
core   +1 more source