Results 151 to 160 of about 304,787 (301)

Refining Tumor Mutational Burden as a Predictive Biomarker for Pembrolizumab: A Real‐World Analysis in Japanese Patients

Cancer Science, EarlyView.
In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda, Mio Yumura, Azusa Hamasaki, Tongyi Fei, Takashi Kubo, Hitoshi Ichikawa, Takashi Kohno, Kuniko Sunami   +7 more
wiley   +1 more source

Protection of goose adiponectin-derived peptide gADP3 on LPS-induced thymus and spleen injury in goose. [PDF]

Poult Sci
Ma B, Cao Z, Yao Z, Zheng Y, Gao M, Luan X.   +5 more
europepmc   +1 more source

Comparative chemical and biological study of essential oils and n-hexane extracts of Thymus vulgaris and Thymus serpyllum (Lamiaceae). [PDF]

Sci Rep
AbdelRazek MMM, Atta AM, Kandil NH, Girgis IEG, Elsayed RTO, Abdel-Latif BRM, Abdel-Halim AE, Salama SGI, Ahmed TEM, AbdelRazek MAS, Foad FH, Elsayed RMS, Aslan SHE, Badawy NIE, Farouk EA, Omran SA, Darwish KM, El-Moghazy SA.   +17 more
europepmc   +1 more source

PLoS One [PDF]

, 2012
Alles, J., Barth, S., Cogliatti, S., Dueck, A., Grasser, F., Imig, J., Meister, G., Motsch, N., Reineke, T., Renner, C., Tinguely, M., Zhu, J.   +11 more
core   +1 more source

Mechanical Insights into the Distinct Effects of Ovariectomy Versus Adrenalectomy on Age-Related Thymic Atrophy in Female Mice. [PDF]

Int J Mol Sci
Chen J, Zhou X, Wei L, Tian Z, Zeng H, Yan F, Zhou J, Zeng X, Meng F, Cao X, Li H, Han X.   +11 more
europepmc   +1 more source

Interleukin‐22 and Interleukin‐18 as Potential Blood Biomarkers in Dupilumab‐Treated Atopic Dermatitis

Allergy, EarlyView.
Ayano Fukushima‐Nomura, Hiroshi Kawasaki, Takehiro Hasegawa, Erika Yanagisawa, Keiji Tanese, Nozomi Yanagida, Shoko Obata, Kiyoshi Yashiro, Yoshihiro Ito, Haruhiko Koseki, Masayuki Amagai   +10 more
wiley   +1 more source

Single Cell Multi‐Omics Revealing the Important Role of MR1 Mediated MAIT Cells in Maintaining Rejection for Liver Transplantation

Cell Proliferation, EarlyView.
This multi‐omics study reveals the significant role of MAIT cells in liver transplant rejection. MAIT cells drive rejection in liver transplantation via the MR1 axis. Their absence reshapes T cell responses and clonal expansion, attenuating allograft injury.
Hailun Cai, Xinqiang Li, Xin Zhou, Xueteng Wang, Zhuoyu Jia, Ruidong Ding, Yurong Luo, Ye Wang, Shipeng Li, Wenxing Sun, Dongxing Wu, Dahong Teng, Kai Zhao, Guanghui Pei, Jinzhen Cai, Bin Wu   +15 more
wiley   +1 more source

Age-related thymic involution: Mechanistic insights and rejuvenating approaches to restore immune function. [PDF]

Sci Adv
Santamaria JC, Irla M.
europepmc   +1 more source

An international consensus on screening and monitoring early‐stage type 1 diabetes: A roadmap to European implementation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease that results in loss of insulin‐secreting pancreatic β‐cells in the islets of Langerhans. A diagnosis of T1D is typically associated with children and adolescents, yet half of all diagnoses of T1D are made in adults.
Sufyan Hussain, Timothy Tree, Chantal Mathieu, Tomasz Klupa, Anna‐Kaisa Tuomaala, Maartje de Wit, Olga Kordonouri, Katarina Braune, Jaivir Pall, Luis Castano, Rachel E. J. Besser, Júlia Galhardo, Francesca Ulivi, Emanuele Bosi, Uroš Bogdanovic, Coralie Alabert, Tadej Battelino   +16 more
wiley   +1 more source

Editorial: Thymus biology: development, immunodeficiency and cancer progression. [PDF]

Front Immunol
He Y, Fan Y, van Oers NS.
europepmc   +1 more source