Results 221 to 230 of about 343,899 (350)
Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen +3 more
wiley +1 more source
Ccl21a, Rather Than Ccl21b, is Essential for Thymocyte Migration in Mouse. [PDF]
Ohigashi I +5 more
europepmc +1 more source
Songorine inhibits mitophagy in chronic heart failure via the TBC1D15/Fis1/Rab7A pathway
Abstract Background and purpose Songorine (SGR) is an alkaloid extracted from Aconitum carichaelii Debx. and has a demonstrated role in cardiac dysfunction. Chronic heart failure (CHF) is a severe clinical syndrome leading to functional impairment and death, primarily due to the deterioration of energy metabolism in cardiomyocytes. However, the precise
Wenxiu Liu +4 more
wiley +1 more source
Traditional Use of Medicinal Plants for Symptom Relief During the COVID-19 Pandemic in Bulgaria. [PDF]
Cherneva D +6 more
europepmc +1 more source
In this study, we investigated the predictive value of tumor mutational burden (TMB) for assessing the efficacy of pembrolizumab in a Japanese cohort. We analyzed real‐world data from 63,952 patients registered in the C‐CAT database who underwent comprehensive genomic profiling, and evaluated the therapeutic efficacy of pembrolizumab in 1899 of these ...
Tomoyo Yasuda +7 more
wiley +1 more source
Thymic Hyperplasias in Practice: Clinical Context, Histological Clues, and Management Implications. [PDF]
Porubsky S.
europepmc +1 more source
The impact of growth hormone (GH) on immunosenescence: exploring the role of B and T cells. [PDF]
Bashir B +6 more
europepmc +1 more source

