Results 101 to 110 of about 25,034 (218)
Infection control in the brain and the eye
Acta Ophthalmologica, EarlyView.Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester +2 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida +7 more
wiley +1 more source
Cancer Science, EarlyView.We report the first successful orthotopic engraftment of human esophageal squamous cell carcinoma in immunosuppressed microminipigs and demonstrate high‐contrast near‐infrared fluorescence endoscopic detection using EGFR‐targeted cetuximab. This large‐animal model bridges preclinical imaging research and future clinical translation in esophageal cancer.
Takanori Miyake +14 more
wiley +1 more source
Thymus’ gland. Clinical, morphological and functional aspects.
Medisur, 2004 This article contains an updated review about the thymus making references to aspects related to its embriologic development, functions, morphology, and hormones the thymus produces and its principal effects, as well as the thymus; involution and its ...
Dunia Reyes Hernández +3 more
doaj +2 more sources
Humphrey Center News: Fall 1989 v. 4, no. 2 [PDF]
, 1989 Newsletter of the Hubert H.
Anthony, Richard P. +1 more
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Cell Proliferation, EarlyView.This multi‐omics study reveals the significant role of MAIT cells in liver transplant rejection. MAIT cells drive rejection in liver transplantation via the MR1 axis. Their absence reshapes T cell responses and clonal expansion, attenuating allograft injury.
Hailun Cai +15 more
wiley +1 more source
Results and observations from the reconstruction of continuous time series of mortality by cause of death [PDF]
Though many countries have been collecting cause-of-death information from death certificates for more than a century, these valuable data sources remain underexplored.
Markéta Pechholdová
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Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation
Cell Proliferation, EarlyView.In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li +14 more
wiley +1 more source
Journal of Gastroenterology and Hepatology, EarlyView.Combined IL‐15 and thymosin α1 therapy reverses CD8+ T cell senescence in hepatocellular carcinoma via a “supply and boost” strategy. Tα1 restores thymic naïve T cell output, while IL‐15 enhances peripheral effector function. Mechanistically, this combination suppresses overactivated PI3K/AKT signaling, restoring antitumor immunity and prolonging ...
Fengtian Wu +5 more
wiley +1 more source
A Link Loss Model for the On-body Propagation Channel for Binaural Hearing Aids
, 2013 Binaural hearing aids communicate with each other through a wireless link for synchronization. A propagation model is needed to estimate the ear-to-ear link loss for such binaural hearing aids.
Chandra, Rohit, Johansson, Anders J
core +1 more source