Results 141 to 150 of about 409,890 (320)
Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications
Cell Proliferation, EarlyView.Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su +5 more
wiley +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Cell Proliferation, EarlyView.Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen +9 more
wiley +1 more source
The clinical case of ectopic thymoma
Известия высших учебных заведений. Поволжский регион: Медицинские наукиThymoma is a rare tumor of the thymus gland. The incidence is 1.3 cases per 1 million population. Only 4% of patients have thymoma in ectopic localization. Only a few such clinical cases have been described in Russia. Differential diagnostics of ectopic
M.G. Fedorova +3 more
doaj +1 more source
European Journal of Clinical Investigation, EarlyView.This review outlines the potential role of anti‐GPCR autoantibodies in MASLD/MASH, given their involvement in a wide range of diseases and their possible contribution to MASLD/MASH pathophysiology. We also focused on anti‐ApoA1 autoantibodies, sharing functional features with anti‐GPCR autoantibodies and have been shown to promote liver steatosis in ...
Sabrina Pagano +3 more
wiley +1 more source
[Problems of thymus neoplasms. Introductory remarks].
Nowotwory, 1975 J Buraczewski
openalex +2 more sources
Emerging roles for integrated stress response signaling in homeostasis
The FEBS Journal, EarlyView.Integrated stress response (ISR), an evolutionarily conserved eukaryotic stress‐adaptive program in eukaryotes, has also been implicated in homeostatic functions. This review covers a broad body of literature and presents several homeostatic functions of ISR in the absence of stress: (a) developmental processes (morphogenesis, differentiation, aging), (
Shyama Nandakumar +2 more
wiley +1 more source
Sketching T cell atlases in the single‐cell era: challenges and recommendations
Immunology &Cell Biology, EarlyView.Recent advances in single‐cell technologies have enabled the creation of T cell atlases, providing detailed maps of adaptive immunity across tissues, development and disease states. These atlases help uncover T cell diversity, functional states and disease mechanisms, aiding in the identification of therapeutic targets.
Itana Bojović +3 more
wiley +1 more source
CD4+ tissue‐resident memory T cells and their role in immunity
Immunology &Cell Biology, EarlyView.In this article, we review and discuss the role of CD4+ tissue‐resident memory T (TRM) cells and their role in immune protection in tissues, such as the lungs, by facilitating pathogen clearance through cytokine production and local immune interactions.
Margarida Kirkby, Marc Veldhoen
wiley +1 more source
BMC Pregnancy and ChildbirthBackground Mucopolysaccharidosis type I (MPS I - IDUA gene) is a rare autosomal recessive lysosomal storage disorder. Clinical symptoms, including visceral overload, are progressive and typically begin postnatally.
Maxime Agranier +10 more
doaj +1 more source
CD73 Expression by CD4+ T Cells Marks Early Effector Memory T Cells
Immunology, EarlyView.The role of CD73 in the development of naïve CD4+ T cells. Naïve CD4+ T cells, which are negative for CD25, CD44, and positive for CD62L, are depicted based on the expression of CD73. CD73− and CD73+ subpopulations among naïve CD4+ T cells bear distinct characteristics.
Luxia Chen +5 more
wiley +1 more source