Results 151 to 160 of about 37,446 (289)

DNA From Neutrophil Extracellular Traps Restricts Group 3 Innate Lymphoid Cells Function in Intestinal Epithelial Repair via CCDC25

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
DNA from neutrophil extracellular traps (NET‐DNA) restricts the function of IL‐22‐dependent ILC3s in intestinal defense through coiled‐coil domain containing protein 25 (CCDC25), which hinders the repair of intestinal epithelial cells and promotes the progression of UC.
Bo Xu, Xuezhou Ke, Xueqian Xie, Qi Yi, Chunjing Li, Meng Zhao, Xiangliang Deng, Qing Wang, Hongxu Chen, Rui Xu, Shuiling Cao, Ying Zhu, Lian Zhou, Qimei Wang, Xia Luo   +14 more
wiley   +1 more source

Synchronous Bilateral Breast Cancer and Thymoma: A Rare Case of Multiple Primary Malignancies. [PDF]

Clin Case Rep
Toogeh G, Aghajani SH, Seyyed Mahmoudi ST, Mortezazadeh M, Zarei H, Nozheh A.   +5 more
europepmc   +1 more source

Manufacturing and clinical applications of non‐CAR‐T immune effector cells

Transfusion, EarlyView.
Thane Kubik, Theodros Mamo, David H. McKenna   +2 more
wiley   +1 more source

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu, Jianwei Wang, Zhiheng Li, Qi Ji, Hui Zhang, Qinyi Zhang, Senlin Zhang, Juanjuan Yu, Yanfang Tao, Yijun Wu, Chunxia Shi, Zong Zai, Zimu Zhang, Yizhen Li, Zhenjiang Bai, Shaoyan Hu, Jian Pan, Yang Yang, Shuiyan Wu   +18 more
wiley   +1 more source

Editorial: Thymus biology: development, immunodeficiency and cancer progression. [PDF]

Front Immunol
He Y, Fan Y, van Oers NS.
europepmc   +1 more source

Mechanisms of Pericyte‐Mediated Cancer Metastasis

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Pericytes play multifarious roles in promoting cancer metastasis by facilitating metastatic cancer cell dissemination, circulating tumor cell survival, tissue extravasation, premetastatic niche formation, and metastatic tumor growth. These cells have intertwined interactions with vascular endothelial cells to modulate cancer cell behavior and ...
Ziheng Guo, Yihai Cao
wiley   +1 more source

Diffuse Myocardial Metastases From Neuroendocrine Malignancy. [PDF]

Cureus
Johnson R, Kanthala N, Burgert-Lon C, Gakhal M.   +3 more
europepmc   +1 more source

Interleukin‐5, Eosinophils, and Interleukin‐5 Pathway Inhibitors in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Volume 78, Issue 6, Page 1196-1205, June 2026.
Interlukin‐5 (IL‐5) plays a crucial role in the pathogenesis of eosinophilic granulomatosis with polyangiitis (EGPA) by promoting eosinophil differentiation, activation, and survival. We present here a typical case of EGPA in which treatment with IL‐5 pathway inhibitors is prescribed, showing to be beneficial for the patient.
Alvise Berti, Christian Pagnoux
wiley   +1 more source

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems.

, 1999
Pten/Mmac1+/- heterozygous mice exhibited neoplasms in multiple organs including the endometrium, liver, prostate, gastrointestinal tract, thyroid, and thymus. Loss of the wild-type allele was detected in neoplasms of the thymus and liver.
Podsypanina, K, Tamura, M, Fisher, Peter, MD, Ellenson, L H, Gu, J, Yamada, K M, Nemes, A, Cordon-Cardo, C, Parsons, R, Catoretti, G   +9 more
core  

Multiple Primary Malignancies in Patients With Gastric Cancer: A Retrospective Study in National Cancer Center of China

Cancer Innovation, Volume 5, Issue 3, June 2026.
This study demonstrates multiple primary malignancies (MPMs) occur in 4.01% of gastric cancer patients and most commonly involve the esophagus, colorectum, and lung. Distinct differences are observed between synchronous and metachronous cases. These findings establish a clinical and epidemiological framework to inform future investigations into MPMs in
Guiling Zhu, Yutong Li, Bingzhi Wang, Liyan Xue, Yuchen Jiao, Xiaobing Wang, Chunxia Du   +6 more
wiley   +1 more source