Results 141 to 150 of about 37,446 (289)
TCF/LEF family transcription factors: Molecular landscape and prognostic scoring in pan‐cancer
This study provides a comprehensive molecular landscape of TCF/LEF family transcription factors across 33 cancer types. We developed a TCF/LEF‐based prognostic score that correlates with immune infiltration, metabolic reprogramming and drug sensitivity, offering a robust transcriptomic signature for predicting patient survival and therapeutic response.
Zhengjun Yang +8 more
wiley +1 more source
Carcinoma showing thymus like differentiation (CASTLE) - A rare thyroid neoplasm
VinodRaosaheb Patil +2 more
openalex +1 more source
Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle +5 more
wiley +1 more source
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider +4 more
wiley +1 more source
Cross‐Level Regulatory Interactions Underlying Human Immune Aging
We performed multi‐omics sequencing on peripheral blood samples from 69 individuals aged 23–75 years and identified multi‐layered molecular interaction networks underlying the process of immune senescence, which provides a comprehensive multi‐omics framework for understanding immune aging and identifying potential strategies to delay immunosenescence ...
Quanyou Wu +9 more
wiley +1 more source
ABSTRACT Background and aims Non‐alcoholic Fatty Liver Disease (NAFLD) affects about a quarter of the world's population. Liver biopsy remains the gold standard for diagnosing the progressive form of NAFLD called Non‐alcoholic Steatohepatitis (NASH) but it is invasive, prone to sampling errors and observer variability, and impractical for widespread ...
Anna Negroni +5 more
wiley +1 more source
Abstract Background and Purpose Drug hypersensitivity reactions (DHRs) associated with a specific human leukocyte antigen (HLA) allotype do not manifest uniformly in all individuals within an HLA model population. This scenario highlights the complexity of predicting drug hypersensitivity reaction risk without considering additional factors ...
Takeshi Susukida +7 more
wiley +1 more source
Multiple lung metastases from typical type A thymoma after long-term follow-up: a case report. [PDF]
Tobari K, Takahashi T, Sano A.
europepmc +1 more source

