Results 171 to 180 of about 37,446 (289)

PPP2R3C serves as a negative regulator associated with reduced T cell hyperactivation and renal protection in lupus

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
Downregulation of PPP2R3C in lupus CD4+ T cells unleashes JNK/c‑Jun and PLCγ1 signalling, driving calcium influx and inflammatory cytokine production. Reconstitution of PPP2R3C expression curbs T cell activation, lowers autoantibody levels and alleviates lupus nephritis, highlighting PPP2R3C as a promising therapeutic candidate. Abstract Background CD4+
Xuan Fang   +8 more
wiley   +1 more source

The Atypical and Suspicious for Malignancy Categories of the WHO Reporting System for Lymph Node, Spleen, and Thymus Cytopathology: Review of their Diagnostic Utility, Limitations, and Clinical Impact

open access: yesDiagnostic Cytopathology, Volume 54, Issue 6, Page 449-460, June 2026.
ABSTRACT Background Fine‐needle aspiration biopsy (FNAB) is the preferred first‐line diagnostic tool for evaluating lymphadenopathy due to its minimally invasive nature and cost‐effectiveness. However, cytopathological interpretation of lymph node FNAB remains challenging because of the wide morphological spectrum of lymphoid lesions.
Immacolata Cozzolino   +5 more
wiley   +1 more source

Mucoepidermoid carcinoma of the thymus: a case report with emphasis on the differential diagnosis. [PDF]

open access: yesPathologica
Pernazza A   +5 more
europepmc   +1 more source

Bibliometric Analysis of Cubebenes and Related Sesquiterpenes: Natural Occurrence, Biosynthesis, Pharmacological Activities, and In‐Silico‐Based Future Therapeutic Potential

open access: yeseFood, Volume 7, Issue 3, June 2026.
Cubebene‐related sesquiterpenes, found across diverse biological sources, exhibit promising pharmacological activities, including anti‐inflammatory, neuroprotective, and anticancer effects. This review highlights their molecular diversity, ADME profiles, and predicted multitarget interactions, underscoring their therapeutic relevance and potential in ...
Khadija Boualam   +4 more
wiley   +1 more source

Benzo[b]fluoranthene Induces Mutation Accumulation and Cancer‐Relevant Mutational Signatures in Mouse Lung Alongside Steady State Levels of Chromosome Damage in Blood

open access: yesEnvironmental and Molecular Mutagenesis, Volume 67, Issue 5-7, June‐August 2026.
ABSTRACT Polycyclic aromatic hydrocarbons (PAHs) are well‐known for their mutagenic and carcinogenic effects. Benzo[b]fluoranthene (BbF) is one of 16 PAHs prioritized by the US Environmental Protection Agency for toxicological evaluation due to pervasive human exposure.
Xinwen Zhang   +10 more
wiley   +1 more source

The Molecular Landscape of CASTLE: A Rare Thymus-like Head and Neck Cancer. [PDF]

open access: yesInt J Mol Sci
Cho WC   +6 more
europepmc   +1 more source

A Review of Extraction, Structural Properties, Biological Activities of Dendrobium chrysotoxum Polysaccharides

open access: yesFood Science &Nutrition, Volume 14, Issue 6, June 2026.
Overview of extraction, biological activities, and application prospects of DCP. (a) Collection, weighing, shearing, and grinding of D. chrysotoxum stems. (b) Aqueous extraction, ultracentrifugation, drying, and filtration to obtain purified DCP. (c) Mechanistic studies and preclinical or retrospective clinical investigations of DCP bioactivities.
Xingshuai Zhang   +4 more
wiley   +1 more source

Age- and tissue-dependent diversity of human plasmacytoid dendritic cells uncovers a cycling subset dominant in early life and cancer. [PDF]

open access: yesImmunity
Antonova AU   +10 more
europepmc   +1 more source

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