Results 181 to 190 of about 600,981 (261)
Protein Posttranslational Modifications in Immunity: Molecular Mechanisms and Therapeutic Targets
Protein posttranslational modifications, including phosphorylation, ubiquitination, SUMOylation, acetylation, methylation, glycosylation, and other new types, dynamically regulate antigen presentation and recognition, immune signal transduction, antibody production and class switching, immune contraction, immune memory establishment, as well as immune ...
Yuxing Yao +10 more
wiley +1 more source
Single Cell and Spatially Resolved Transcriptome and Immune Repertoire of Mouse Thymus During Aging Reveal Immunological Heterogeneity and Direction of Thymic Selection Pressure. [PDF]
Fang J +14 more
europepmc +1 more source
This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei +9 more
wiley +1 more source
Mechanism and intervention strategy of thymus atrophy in cancer immunotherapy. [PDF]
Zhang H, Zhang F, Li T, Xu S, Cui L.
europepmc +1 more source
Magnetic Nanomedicine for Cancer: Mechanisms, Modalities, and Translation
At the convergence of nanotechnology, precision oncology and intelligent therapeutics, magnetic nanoparticles (MNPs) are redefining how cancer is detected, targeted and treated. This review critically examines the mechanisms enabling their integration in imaging, targeted drug delivery and magnetic hyperthermia, while exploring how intelligent design ...
Shivani Kadam +10 more
wiley +1 more source
RT‐immunotherapy synergy for thoracic tumors relies on precise target delineation to protect immune components. IFI, reduced volumes, and optimized positioning minimize damage, while multimodal imaging, DL, PBT, and FLASH‐RT enhance control. These innovations shift RT to an immune‐centric model, improving lung and esophageal cancer outcomes.
Xiaoying Chen +3 more
wiley +1 more source
Pathobiology of thymic epithelial tumours and the treatment strategy based on immuno-oncological characteristics: a narrative review. [PDF]
Okada S +4 more
europepmc +1 more source
XIST Is a Key Modulator Associated With the Adhesome Network
CRISPRi‐mediated knockdown of XIST in OVCAR3 ovarian cancer cells alters adhesome gene expression, supporting a functional connection between XIST and cell adhesion programs. Building on this finding, transcriptomic analyses of GTEx and TCGA datasets reveal that XIST is strongly coordinated with the adhesome network across normal tissues, whereas this ...
Dongning Chen +3 more
wiley +1 more source
Immunotherapy of cancer without induction of autoimmunity - CD6 as a therapeutic target. [PDF]
Fox DA, Gurrea-Rubio M.
europepmc +1 more source

