Results 201 to 210 of about 600,981 (261)

Women in space: A review of known physiological adaptations and health perspectives

Experimental Physiology, Volume 111, Issue 9, Page 3944-3967, 1 September 2026.
Abstract Exposure to the spaceflight environment causes adaptations in most human physiological systems, many of which are thought to affect women differently from men. Since only 11.5% of astronauts worldwide have been female, these issues are largely understudied.
Millie Hughes‐Fulford, Danielle J. Carroll, Heather C. M. Allaway, Bonnie J. Dunbar, Aenor J. Sawyer   +4 more
wiley   +1 more source

Synchronous Bilateral Breast Cancer and Thymoma: A Rare Case of Multiple Primary Malignancies. [PDF]

Clin Case Rep
Toogeh G, Aghajani SH, Seyyed Mahmoudi ST, Mortezazadeh M, Zarei H, Nozheh A.   +5 more
europepmc   +1 more source

Re‐evaluation of salt of aspartame‐acesulfame (E 962) as food additive

EFSA Journal, Volume 24, Issue 9, September 2026.
Abstract The present opinion deals with the re‐evaluation of salt of aspartame‐acesulfame (E 962) as a food additive. The Panel considered that upon ingestion, E 962 dissociates into aspartame and acesulfame ions which correspond to those of the authorised sweeteners aspartame (E 951) and acesulfame K (E 950). The Panel therefore assessed the safety of
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Lourdes Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, Maria Jose Frutos Fernandez, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Ellen Bruzell, Cristina Fortes, Kevin James Chipman, Riccardo Crebelli, Peter Fürst, Jean‐Charles Leblanc, Evangelia Ntzani, Andrea Terron, Matthew Wright, Stefania Barmaz, Costanza Bonnici, Consuelo Civitella, Elena Mazzoli, Josef Daniel Rasinger, Ana Rincon, Camilla Smeraldi, Alexandra Tard, Federica Lodi   +34 more
wiley   +1 more source

Editorial: Thymus biology: development, immunodeficiency and cancer progression. [PDF]

Front Immunol
He Y, Fan Y, van Oers NS.
europepmc   +1 more source

Proline‐Derived N‐Heterocyclic Carbene Gold(I) Complexes With Dual DNA Binding and Thioredoxin Reductase Inhibition

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Proline‐derived Au(I)–NHC complexes display potent anticancer activity against lung and triple‐negative breast cancer cells. The cationic complexes promote DNA intercalation, thioredoxin reductase inhibition, ROS overproduction, and mitochondrial membrane depolarization, ultimately triggering apoptotic cell death through a multimodal mechanism of ...
Giacomo Cassarà, María Gil‐Moles, Thomas Scattolin, M. Concepción Gimeno   +3 more
wiley   +1 more source

A single-cell atlas revealing cellular heterogeneity across healthy and diseased human thymus. [PDF]

Nat Commun
Direder M, Wielscher M, Salek M, Laggner M, Copic D, Klas K, Bormann D, Golabi B, Kühtreiber H, Lingitz MT, Müllauer L, Schiefer AI, Weninger W, Aigner C, Ankersmit HJ, Mildner M, Moser B.   +16 more
europepmc   +1 more source

Reversible Coordination Modes in Piperazine‐Based Ru(II)‐p‐Cymene Acylthiourea Complexes: Modulating DNA Groove Binding for Selective Antimelanoma Activity

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Piperazine‐based monodentate and S,N‐bidentate Ru(II)‐p‐cymene complexes were synthesized through distinct coordination strategies and evaluated for antimelanoma activity. Among the investigated compounds, the S,N‐bidentate complex 2b exhibited significantly enhanced cytotoxicity (IC50 = 6.1 ± 0.8 ) against melanoma cells, particularly the A375 cell ...
Amir Karim, Xin Wang, Yu‐Ting Chu, Rahimeh Eshaghi Malekshah, En‐De Shu, Najeeb Ullah, Chien‐Chih Chiu, Ching‐Ming Chien, Sodio C. N. Hsu   +8 more
wiley   +1 more source

Optimized detection of caspase-6 activation in a murine inflammation model to inform neurodegenerative disease therapies. [PDF]

PLoS One
Sagarbarria I, Seo J, Smith AJ, Vazey EM, Tremblay KD, Mager J, Hardy JA.   +6 more
europepmc   +1 more source

GW9508-Induced Activation of GPR40 in Thymic Epithelial Cells: A Therapeutic Strategy to Delay Thymic Aging. [PDF]

Aging Cell
Li Q, Zhu P, Cui L, Luo F, Zhou Y, Hu Y, Luo C, Han S, Ding X, Yao M, Yuan H, Song Y.   +11 more
europepmc   +1 more source

Mediastinal epithelial neoplasms with recurrent molecular alterations. [PDF]

Mediastinum
Mikula MW, Baraban E.
europepmc   +1 more source