Results 191 to 200 of about 37,446 (289)

Quality of Life in a Swedish Cohort of Patients with Mycosis Fungoides. [PDF]

open access: yesActa Derm Venereol
Hub D, Drott K, Belfrage E, Sonesson A.
europepmc   +1 more source

Evaluation of Photophysical Properties and Biological Applications of Diarylmethanes

open access: yesChemistryOpen, Volume 15, Issue 6, June 2026.
The wide applications of diarylmethanes were investigated through various experimental and computational approaches. The solvent environment influences the electronic properties of diarylmethanes and hence their drug‐like properties. Interactions with PARP1 revealed stable binding supporting anticancer potential.
H. Ranjini Jenifer   +2 more
wiley   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang   +6 more
wiley   +1 more source

TCRγ constant usage tunes human γδ T cell antigen sensitivity, thymic programming, and peripheral function. [PDF]

open access: yesSci Immunol
Viswanathan M   +14 more
europepmc   +1 more source

Synchronous Surgical Therapy for Bilateral Multiple Pulmonary Nodules: A Single‐Center Analysis of 108 Cases

open access: yesThoracic Cancer, Volume 17, Issue 11, June 2026.
The study included 108 patients admitted to Peking University Third Hospital from January 2015 to December 2025. The most common surgical combination was wedge resection + wedge resection (44.4%). The mean postoperative hospital stay was 6.55 ± 3.03 days. Severe complications Less than 5%. No 30‐day mortality or unplanned secondary surgery.
Huayu He   +12 more
wiley   +1 more source

Immunosenescence and Vaccine Efficacy in Aging: Dynamic Interplay of Gut Microbiota and mTOR Signaling Pathways

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
Aging impairs vaccine efficacy through gut microbiota dysbiosis and mTOR hyperactivation, which together drive inflammaging and weaken immune memory. This review highlights the bidirectional microbiota–mTOR axis and proposes that combining mTOR inhibitors with microbiota modulation offers a promising strategy to enhance vaccine responses in older ...
Jiaxuan Li   +5 more
wiley   +1 more source

T Cell Dysfunction in the Acidic Tumor Microenvironment

open access: yesActa Physiologica, Volume 242, Issue 6, June 2026.
ABSTRACT Solid tumors are characterized by profound metabolic and vascular abnormalities that generate a hostile tumor microenvironment (TME) marked by extracellular acidosis, hypoxia, and nutrient deprivation. While the consequences of these conditions for cancer cell behavior have been extensively studied, their impact on anti‐tumor immune responses ...
F. B. Christiansen   +4 more
wiley   +1 more source

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