Results 191 to 200 of about 600,981 (261)

A Mechanism‐Based Framework for Anti‐Aging Strategies: From Metabolic Regulation to Senotherapy and Stem Cell‐Based Interventions

Aging Cell, Volume 25, Issue 9, September 2026.
The aging of the human body is a complex process driven by multiple contributing factors. Based on their underlying mechanisms, current anti‐aging interventions can be classified into six primary categories. This paper summarizes the most promising anti‐aging strategies within each class. ABSTRACT The global prevalence of aging and age‐related diseases
Feifei Li, Yankai Wang, Gelin Wang, Jiguo Chen, Song Huang   +4 more
wiley   +1 more source

The Heart of the Thymus: A Rare Tale of Nonischemic Cardiomyopathy in the Absence of Myasthenia Gravis. [PDF]

Clin Case Rep
Barman M, Al Hariri B, Babiker T, Gadkarem M, Alhariri J, Alharafsheh A.   +5 more
europepmc   +1 more source

Peripheral κ opioid receptor in pain and inflammation: From molecular signalling and gene expression to drug discovery

British Journal of Pharmacology, Volume 183, Issue 17, Page 5157-5189, September 2026.
The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan, Elena C. A. Becker, Boglarka B. Bata, Christian W. Gruber   +3 more
wiley   +1 more source

A Transcriptomic Analysis of Human iPSC-Derived Parathyroid Lineage Cells Reveals Limited Maturation Beyond the Parathyroid-Thymic Primordium. [PDF]

Cells
Kise C, Nakatsuka R, Kawamoto A, Sasaki Y, Hitomi H, Takahashi K, Nozaki T.   +6 more
europepmc   +1 more source

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

Cell Proliferation, Volume 59, Issue 9, September 2026.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li, Zhixi Chen, Jie Chen, Xingwei Zhang, Jiamian Zheng, Zirui Liu, Meixue Pan, Yue Li, Bo Yu, Shaohua Chen, Jing Lai, Xianfeng Zha, Liye Zhong, Yikai Zhang, Yangqiu Li   +14 more
wiley   +1 more source

Multiple lung metastases from typical type A thymoma after long-term follow-up: a case report. [PDF]

J Cardiothorac Surg
Tobari K, Takahashi T, Sano A.
europepmc   +1 more source

Structural T‐Cell Receptor Analysis in the Age of Machine Learning

Immunological Reviews, Volume 342, Issue 1, September 2026.
ABSTRACT The development of highly accurate deep learning models for protein structure prediction has transformed the landscape of T‐cell receptor (TCR) structure data, which can now be accessed at repertoire scale. We provide a perspective on the growing field of structural TCR immunoinformatics, summarizing core principles of TCR structural biology ...
Nele P. Quast, Matthew I. J. Raybould, Charlotte M. Deane   +2 more
wiley   +1 more source

Thymoma arising within a unilocular thymic cyst during follow-up: a report of a resected case. [PDF]

Int J Surg Case Rep
Maeda R, Sato Y, Hazemoto T, Tsuruta T, Yamada R, Inomata M.   +5 more
europepmc   +1 more source

A rare giant large cell neuroendocrine carcinoma: an ITMIG Tumor Board case report from a Turkish multidisciplinary team. [PDF]

Mediastinum
Cangir AK, Sak SD, Güneş G, Çoruh AG, Dursun Ş, Akyürek S, Köksoy EB, Van Raemdonck D, Strange C, Arrossi A, Roden AC, Rajan A, Komaki R, Shepherd A.   +13 more
europepmc   +1 more source

Cancer Risk and Cause-Specific Mortality Among People With Thymoma in the United States. [PDF]

J Thorac Oncol
Tao J, Loehrer PJ, Cho A, Lee C, Morton LM, Kooshesh KA, Gustafsson K, Scadden DT, Engels EA.   +8 more
europepmc   +1 more source