Results 171 to 180 of about 20,766 (259)

The Imbalance Between Tumor Immunosurveillance and Tumor Immune Escape in Glioblastoma

open access: yesImmunology &Cell Biology, EarlyView.
(Left)The identification and elimination of tumour cells is enabled by the infiltration of functional innate and adaptive immune effectors into the TME, such as natural killer cells (NK cells) and cytotoxic T cells (CD8 T cells). Effective innate and adaptive immune responses facilitate immunological control of malignant outgrowth.
Sarah J. MacDonald   +6 more
wiley   +1 more source

The Transcription Factor EGR2 Plays a Central Role in the Expansion and Function of TCRαβ+CD4−CD8− Double Negative T Cells in lpr Lupus Mice

open access: yesImmunology, EarlyView.
The highly expanded TCRβ+ DNT cells in autoimmune‐prone B6/lpr mice are phenotypically and functionally different from the TCRβ+DNT cells of normal B6 mice. Conditional Egr2 deletion in B6/lpr mice not only reduces TCRβ+ DNT cell numbers but also tends to correct the phenotypic and functional abnormalities of DNT cells in B6/lpr mice. In addition, Egr2
Rujuan Dai   +4 more
wiley   +1 more source

Patterns of Interploidy Admixture in Polyploid Complexes: Insights From Thymus Sect. Mastichina (Lamiaceae). [PDF]

open access: yesMol Ecol
García-Cárdenas FJ   +7 more
europepmc   +1 more source

Aire and Fezf2 Shape the Medullary Thymic Epithelial Cell Immunopeptidome for Central Tolerance

open access: yesImmunology, EarlyView.
Central tolerance is shaped not merely by promiscuous gene expression in medullary thymic epithelial cells (mTECs), but by the subset of self‐peptides ultimately presented on MHC class II molecules. We propose a multilayered framework in which AIRE/Aire and FEZF2/Fezf2, together with specialised differentiation programmes—including thymic mimetic‐cell ...
Geraldo Aleixo Passos   +5 more
wiley   +1 more source

Perceiving Vegetation From Social Positions: Discourses on Plants in a Mediterranean Landscape

open access: yesSociology Lens, EarlyView.
ABSTRACT Understanding how vegetation is perceived, named and valued requires attention to the social positions from which these perceptions are produced. This article analyses vegetation perception from different social positions based on qualitative research conducted in the province of Jaén (Andalusia, Spain), a Mediterranean landscape characterized
Javier Jurado‐Pardeiro   +3 more
wiley   +1 more source

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