Results 41 to 50 of about 79,494 (311)

Recent advances in managing differentiated thyroid cancer [PDF]

open access: yes, 2018
The main clinical challenge in the management of thyroid cancer is to avoid over-treatment and over-diagnosis in patients with lower-risk disease while promptly identifying those patients with more advanced or high-risk disease requiring aggressive ...
Durante, Cosimo   +3 more
core   +2 more sources

THYROGLOBULIN AS A TUMOR MARKER IN DIFFERENTIATED THYROID CANCER – CLINICAL CONSIDERATIONS

open access: yesActa Clinica Croatica, 2018
SUMMARY – Initial treatment of the majority of patients with differentiated thyroid cancer (DTC) includes total thyroidectomy. Postoperative ablation therapy with radioactive iodine (I-131) is indicated in all high-risk patients, however, there is ...
M. Prpić   +4 more
semanticscholar   +1 more source

Thyroid Autoantibodies Display both “Original Antigenic Sin” and Epitope Spreading

open access: yesFrontiers in Immunology, 2017
Evidence for original antigenic sin in spontaneous thyroid autoimmunity is revealed by autoantibody interactions with immunodominant regions on thyroid autoantigens, thyroglobulin (Tg), thyroid peroxidase (TPO), and the thyrotropin receptor (TSHR) A ...
Sandra M. McLachlan, Basil Rapoport
doaj   +1 more source

Detection of thyroglobulin in fine-needle aspiration for diagnosis of metastatic lateral cervical lymph nodes in papillary thyroid carcinoma: A retrospective study

open access: yesFrontiers in Oncology, 2022
ObjectiveWe analysed the diagnostic performance of thyroglobulin in fine-needle aspiration (FNA-Tg) in the suspicious lateral cervical lymph nodes (CLNs) in patients with papillary thyroid cancer (PTC), proposed the best cutoff value and discussed the ...
Yuxuan Wang   +13 more
doaj   +1 more source

Use of thyroglobulin as a tumour marker

open access: yesWorld Journal of Biological Chemsitry, 2017
It is worthwhile to measure serum thyroglobulin (TG) level in thyroid cancer before subjecting patients to surgery for two reasons. Firstly, if the level is high, it may give a clue to the local and metastatic tumour burden at presentation; secondly, if ...
Buddhike Sri Harsha Indrasena
semanticscholar   +1 more source

A Novel Mutation in the Thyroglobulin Gene Resulting in Neonatal Goiter and Congenital Hypothyroidism in an Eritrean Infant

open access: yesJCRPE, 2022
Congenital hypothyroidism (CH) due to dyshormonogenesis may occur due to mutations in any of the key genes involved in thyroid hormone biosynthesis (TG, TPO, DUOX2, DUOXA2, SLC5A5, IYD, SLC26A4 and SLC26A7).
Eve Stern   +5 more
doaj   +1 more source

Thyroglobulin for Monitoring for Thyroid Cancer Recurrence.

open access: yesJournal of the American Medical Association (JAMA), 2019
The thyroid gland is located in the lower front part of the neck above the breastbone and regulates metabolism through production of thyroid hormones (T3 and T4).
A. Peiris, Dillon Medlock, M. Gavin
semanticscholar   +1 more source

Value of 18F-FDG Hybrid PET/MR in Differentiated Thyroid Cancer Patients with Negative 131I Whole-Body Scan and Elevated Thyroglobulin Levels

open access: yesCancer Management and Research, 2021
Hongyan Li,1,2 Xiaomin Chen,1,2 Yajing Zhang,1,2 Kun Wang,1,2 Zairong Gao1,2 1Department of Nuclear Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, People’s Republic of China; 2Hubei ...
Li H, Chen X, Zhang Y, Wang K, Gao Z
doaj  

PROGNOSTIC VALUE OF IMMUNOLOGICAL AND GENETIC TESTING IN THE I TRIMESTER OF PREGNANCY COMPLICATED BY SUBCHORIONIC HEMATOMA

open access: yesОпухоли женской репродуктивной системы, 2017
Introduction. Pregravid preparation plays a main role in solving issues with recurrent miscarriage and preterm delivery. Detection of etiologic factors of miscarriage with development of preventive strategies seems reasonable.Study objective was to ...
M. V. Utrobin, S. V. Yur’ev
doaj   +1 more source

Breaking tolerance in transgenic mice expressing the human TSH receptor A-subunit: thyroiditis, epitope spreading and adjuvant as a 'double edged sword'. [PDF]

open access: yes, 2012
Transgenic mice with the human thyrotropin-receptor (TSHR) A-subunit targeted to the thyroid are tolerant of the transgene. In transgenics that express low A-subunit levels (Lo-expressors), regulatory T cell (Treg) depletion using anti-CD25 before ...
Aliesky, Holly A   +4 more
core   +2 more sources

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