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2021 update on thyroid-associated ophthalmopathy
Journal of Endocrinological Investigation, 2021Our understanding of thyroid-associated ophthalmopathy (TAO, A.K.A Graves' orbitopathy, thyroid eye disease) has advanced substantially, since one of us (TJS) wrote the 2010 update on TAO, appearing in this journal.PubMed was searched for relevant articles.Recent insights have resulted from important studies conducted by many different laboratory ...
E. J. Neag, T. J. Smith
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Octreoscan in Thyroid-Associated Ophthalmopathy
Thyroid, 2002Until recently, there was no imaging technique available that could be considered as a reliable measure of inflammation in thyroid-associated opthalmopathy (TAO). Pentetreotide (a synthetic derivative of somatostatin) labeled with 111In has been used to visualize somatostatin receptors in endocrine-related tumours in vivo.
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Azathioprine in the treatment of thyroid-associated ophthalmopathy
Acta Endocrinologica, 1990Abstract Azathioprine is used in the treatment of thyroid-associated ophthalmopathy, but its effectiveness has not been evaluated. In the present study 20 patients with moderately severe ophthalmopathy were recruited; 10 patients received azathioprine and the other 10 matched patients served as controls. During the treatment period (lasting 1 year) and
P, Perros +3 more
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Medical Treatment for Thyroid-Associated Ophthalmopathy
Thyroid, 2002The medical management of thyroid-associated ophthalmopathy has been, and remains a clinical challenge. Several drugs have been used. Systemic steroids seem to be beneficial in patients with active disease. The evidence for the remaining drugs reported to be potentially useful, is unconvincing.
Petros, Perros, Pat, Kendall-Taylor
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Natural history of thyroid associated ophthalmopathy
Clinical Endocrinology, 1995SummaryBACKGROUND The natural history of thyroid associated ophthalmopathy is poorly documented, although It is widely thought that many cases Improve spontaneously with time. This has Important Implications in the management of patients and is also a critical factor when assessing the effects of different treatments.OBJECTIVE To document the natural
P, Perros +2 more
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Thyroid-Associated Ophthalmopathy
2011Eye symptoms are a common feature of Graves’ disease, where the symptoms have an underlying immunological cause. Several designations have been used: endocrine ophthalmopathy, dysthyroid orbitopathy, dysthyroid ophthalmopathy, orbitopathy, infiltrative ophthalmopathy and thyroid-associated ophthalmopathy (TAO).
Ernst Nyström +4 more
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The Diagnosis and Treatment of Thyroid-Associated Ophthalmopathy
Aesthetic Plastic Surgery, 2011Little is written in the plastic surgery literature about thyroid-associated ophthalmopathy (TAO), a condition that is separate from Graves-Basedow disease and may not be accompanied by hyperthyroidism. Many patients with this disease frequently seek periocular aesthetic reconstruction prior to medical workup.This study presents a comprehensive review ...
Daniel J, Gould +2 more
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Sinusitis in Thyroid Associated Ophthalmopathy
American Journal of Rhinology, 1993In 19 patients with thyroid associated ophthalmopathy undergoing orbital decompression, histologic examination of paranasal sinus mucosa revealed moderate to severe inflammatory alterations in all patients. Only 2/19 patients had a history of chronic sinusitis. In 4/19 patients, mucosal abnormalities of the paranasal sinuses were found on preoperative
S. Davris +3 more
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Animal Models of Thyroid-Associated Ophthalmopathy
Thyroid, 2002Thyroid-associated ophthalmopathy (TAO) is an autoimmune condition most frequently associated with Graves' disease (GD). The thyrotropin receptor (TSHR) is an important target of the autoimmune response in both disorders. The last 5 years have seen some progress in the development of animal models, induced with TSHR preparations and reproducing some or
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Progress in Thyroid-Associated Ophthalmopathy
Thyroid, 2002185 AN INTERNATIONAL SYMPOSIUM on progress in thyroid-associated ophthalmopathy (TAO) was held as a satellite to the 12th International Thyroid Congress, in Kyoto. The program addressed basic research and clinical management aspects of TAO. The symposium comprised 19 invited lectures and a poster session.
Yuji Hiromatsu, Jack R. Wall
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