Results 61 to 70 of about 8,157,530 (188)

Progress in the pathogenesis of thyroid-associated ophthalmopathy and new drug development

Taiwan Journal of Ophthalmology, 2020
Thyroid-associated ophthalmopathy (TAO) is the most common extrathyroidal manifestation of toxic diffuse goiter (Graves' disease), also known as Graves' ophthalmopathy/orbitopathy. As an organ-specific autoimmune disease, the pathogenesis of TAO is still
Yazhuo Huang, Sijie Fang, Shuo Zhang, Huifang Zhou   +3 more
doaj   +1 more source

Differential Diagnosis of Thyroid Dermopathy and Acropachy with Arthritis

Türk Osteoporoz Dergisi, 2021
Thyroid acropachy is a rare manifestation of autoimmune thyroid disease with characteristic imaging findings. Clinically, it is almost always associated with thyroid ophthalmopathy and dermopathy.
Nurdan Yılmaz, Pelin Gümüş Ok
doaj   +1 more source

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, Volume 13, Issue 4, 19 January 2026.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

A Pruritic Predicament: An Unusual Presentation of Graves’ Disease Complicated by Pregnancy

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
Pruritus is a known but uncommon symptom of hyperthyroidism that can be misinterpreted or overlooked in a patient presentation. This is a case report of a 40‐year‐old female who presents with a 3‐month history of severe, worsening pruritus. Further history demonstrated potential signs of hyperthyroidism, and laboratory values demonstrated low TSH ...
Rob Lawless, Evan Smith, Camryn Slone, Thaddeus Salmon, Semonti Nandi   +4 more
wiley   +1 more source

Thyroid-associated ophthalmopathy and TSH receptor autoantibodies in nonmetastatic thyroid cancer after total thyroidectomy.

, 2008
In a 58-year-old woman with nontoxic nodular goiter, a fine-needle aspiration biopsy showed the presence of papillary thyroid cancer, which was treated with total thyroidectomy in June 2000 and a subsequent ablative dose of 131-radioiodine. A posttherapy
Tolari S, ANTONELLI, ALESSANDRO, FERRANNINI, ELEUTERIO, Fallahi P, Ferrari SM   +4 more
core   +1 more source

Lugol’s Iodine as a Key Treatment in Transient Gestational Thyrotoxicosis: A Case Report

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Introduction Transient gestational thyrotoxicosis (TGT) occurs when human chorionic gonadotropin (hCG) directly stimulates the maternal thyroid gland during the first trimester of pregnancy. We report a case of complicated TGT in a young woman who required treatment with Lugol’s solution.
Mariam Mabrouk, Najla Bchir, Dorra El Guiche, Anaam Ben Chehida, Emna Mraihi, Chadia Zouaoui, Haroun Ouertani, Mohammad Shahangir Biswas   +7 more
wiley   +1 more source

Ophthalmological evaluation in thyroid‐associated ophthalmopathy [PDF]

Acta Ophthalmologica Scandinavica, 2003
Abstract.Purpose:  Thyroid‐associated ophthalmopathy (TAO) is an autoimmune disorder associated with Graves' disease and can seriously decrease quality of life. Current therapeutic regimens have considerable side‐effects and are not always able to restore normal function and appearance.
openaire   +2 more sources

Unilateral Graves’ Disease Developing During Treatment With Tirzepatide in a Patient With Diabetes: A Case Report

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Background Tirzepatide is a dual agonist of the glucose‐dependent insulinotropic polypeptide (GIP) receptor and glucagon‐like peptide‐1 (GLP‐1) receptor, demonstrates significant efficacy in lowering blood glucose levels and reducing body weight. Consequently, its use has increased among patients with type 2 diabetes and obesity.
Yusuke Deto, Ryo Hasegawa, Shoya Ino, Satoru Shibata, Kouhei Ohno, Takahito Itoh, Tomoaki Matsumoto, Takayuki Miki, Kalyani Sen   +8 more
wiley   +1 more source

Managing Nasal Ischemia and Necrosis Post‐Triamcinolone Injection: A New Case Series

Case Reports in Otolaryngology, Volume 2026, Issue 1, 2026.
Nasal ischemia following cosmetic injections has been reported in several cases. Postsurgery triamcinolone administration in the nasal region is a common practice to reduce inflammation and address pollybeak deformity. While cases of retinal artery occlusion following triamcinolone injection have been documented, this case series presents the first ...
Shahriar Nazari, Nima Hadadian, Foroohe Bayatparidary, Seied Omid Keyhan, Mohammadamin Damsaz, Nabil Fakih-Gomez, Mohammad Reza Pourani, Rong-San Jiang   +7 more
wiley   +1 more source

Diagnosis, Follow-Up and Treatment Results in Thyroid Ophthalmopathy

, 2015
Objectives: To discuss our follow-up and treatment results in thyroid-associated ophthalmopathy (TAO). Materials and Methods: The records of 168 TAO cases who were followed at our clinic between October 1998 and October 2013 were reviewed ...
Kaan Gündüz, Savku, Esra, Esra Savku, Gündüz, Kaan   +3 more
core   +1 more source