Results 171 to 180 of about 14,074 (215)

Thyroid stimulating immunoglobulin (TSI) synthesis by pokeweed mitogen (PWM) stimulated peripheral blood lymphocytes (PBL) from Graves' disease (GD) patients.

, 1986
Brigitte Pautard, Jean‐Michel Remy, J Charreire   +2 more
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Relationship between thyroid stimulating hormone and thyroid stimulating immunoglobulin in Graves’ hyperthyroidism

Journal of Endocrinological Investigation, 2010
In Graves' hyperthyroidism, suppression of serum TSH after restoration of normal serum T4 and T3 with treatment has been attributed to binding of TSH-receptor antibodies to TSH receptors in the pituitary. Accordingly, the relationship between TSH and serum thyroid stimulating immunoglobulin (TSI) was examined during follow-up of patients with Graves ...
Kenneth A Woeber
exaly   +3 more sources

A Reconsideration of a Thyroid-Stimulating Immunoglobulin as the Cause of Hyperthyroidism in Graves' Disease

Journal of Clinical Endocrinology and Metabolism, 1976
Several assays for thyroid-stimulating immunoglobulins in the blood in patients with Graves' disease have been described recently; depending upon the method, different names have been used and distinct entities thus implied. Using an increase in cyclic AMP in the human thyroid slice after 2 h of incubation as an index of thyroid stimulation, we ...
J M Mckenzie, M Zakarija, Mckenzie J M
exaly   +3 more sources

Thyroid Stimulating Immunoglobulin is Often Negative in Children with Graves' Disease

Journal of Pediatric Endocrinology and Metabolism, 2008
The diagnosis of Graves' disease (GD) is typically confirmed with a thyroid stimulating immunoglobulin (TSI) titer. While TSI is reported to be positive in >90% of patients with GD, our anecdotal experience suggests that TSI negative GD may be more common in children.To investigate the incidence of TSI negative GD in our population and to compare ...
Erica A Eugster
exaly   +3 more sources

Thyroid-Stimulating Immunoglobulins

Hormone Research, 2008
The presence of thyroid-stimulating immunoglobulins in patients with Graves’ disease is well established. Considerable evidence has accumulated that these immunoglobulins are antibodies to a thyroid plasma membrane antigen whose precise nature remains to be identified.
Pinchera A, Fenzi GF, Macchia E, Bartalena L, MARIOTTI, STEFANO, Monzani F.   +5 more
openaire   +4 more sources

THYROID-STIMULATING IMMUNOGLOBULINS IN GRAVES' DISEASE

The Lancet, 1974
Abstract A receptor assay for T.S.H. using human thyroid membranes and receptor-purified 125 I-labelled T.S.H. was used to study the interaction of Graves' immunoglobulins with thyroid membranes. Immunoglobulins from twenty-two of twenty-five patients with Graves' disease clearly inhibited the binding of T.S.H. to human thyroid membranes. Significant
B R, Smith, R, Hall
openaire   +2 more sources

Test Utilization for Thyroid Stimulating Hormone Receptor Antibody and Thyroid Stimulating Immunoglobulin Assays in Korea

Clinical Laboratory, 2021
We aimed to investigate test utilization of the competition-based M22 thyroid-stimulating hormone receptor antibody (M22-TSH Rc Ab) and thyroid stimulating immunoglobulin (TSI) bioassay in Korea.We retrospectively reviewed data on M22-TSH Rc Ab assays and TSI assays from the laboratory information system between January 1, 2015, and June 30, 2020 ...
Rihwa, Choi, YeJin, Oh, Sukjung, Lee, Gowun, Ryu, Sang Gon, Lee, Eun Hee, Lee   +5 more
openaire   +2 more sources

THYROID‐STIMULATING IMMUNOGLOBULINS IN OPHTHALMIC GRAVES'DISEASE

Clinical Endocrinology, 1977
SUMMARYThyroid‐stimulating immunoglobulins (TSI) have been detected by receptor assay in the sera of 43% of patients with ophthalmic Graves’disease. Comparison of the receptor assay studies with thyroid function tests indicated that in several patients the antibodies detected by receptor assay were biologically inactive.
C S, Teng, B R, Smith, B, Clayton, D C, Evered, F, Clark, R, Hall   +5 more
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Thyroid Stimulating Immunoglobulins

Acta clinica Belgica, 1981
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Fenzi GF, MARIOTTI, STEFANO, Bartalena L, DeGroot LJ   +3 more
openaire   +4 more sources