Results 91 to 100 of about 1,147,749 (362)
Advances and Strategies in Enhancing mRNA Cancer Vaccines
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang+4 more
wiley +1 more source
Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]
To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E.+2 more
core +1 more source
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng+17 more
wiley +1 more source
DOES STILL EXIST A CORRELATION BETWEEN X-RAYS OCCUPATIONAL EXPOSURE AND BENIGN NODULAR THYROID DISEASE? [PDF]
Objective: The prevalence of benign nodular thyroid disease in the general population is high, as shown by various studies, and the diagnosis is eased by the improved diagnostic capacity of the instruments used.
Lo Baido Chiara+2 more
core +1 more source
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba+20 more
wiley +1 more source
A study of serum IgG4 levels in the clinical metamorphosis of autoimmune thyroid disease
Background: Measurement of serum IgG4 had been suggested to distinguish the unique subtypes of autoimmune thyroid disease (AITD) which demonstrated patterns of fluctuating between hyperthyroidism and hypothyroidism. However, the clinical utility of serum
Yotsapon Thewjitcharoen+7 more
doaj +1 more source
Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study [PDF]
© 2017 Endocrine Society. Background: Soy protein with isoflavones appears to have an adverse effect on thyroid function, but it is not known whether it is the protein or isoflavone component that is deleterious.
Atkin, Stephen L.+4 more
core +1 more source
Contemporary electronic devices produce significant waste, harming ecosystems. Innovation in design, consumption, materials, and end‐of‐life management is crucial. This review explores advanced materials for sustainable and responsible electronics, highlighting their potential to reduce environmental and health hazards while improving device ...
Rawan Omar+7 more
wiley +1 more source
IntroductionAlthough active vitamin D (VD) has been used both preoperatively and postoperatively to prevent hypocalcemia risk in patients undergoing total thyroidectomy, the role of 1,25-dihydroxyvitamin D (1,25(OH)2D) has not been examined.
Hiroyuki Yamashita+7 more
doaj +1 more source
Thyroid Antibodies and Thyroiditis [PDF]
G. A. Smart, S. G. Owen
openaire +3 more sources