Results 91 to 100 of about 1,147,749 (362)

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]

open access: yes, 1996
To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E.   +2 more
core   +1 more source

Peptide Coacervates with Metal–Phenolic Membranes Modulate Glucose Metabolism and Enhance Cancer Immunotherapy

open access: yesAdvanced Materials, EarlyView.
Peptide coacervates encapsulated with interferon‐α and membranized with metal–phenolic networks (PC‐IFNα@MPNs) are designed to reprogram glucose competition between tumor and cytotoxic T cells. This metabolic modulation enhances immunotherapy by suppressing tumor glycolysis and boosting T cell effector function.
Xin Zheng   +17 more
wiley   +1 more source

DOES STILL EXIST A CORRELATION BETWEEN X-RAYS OCCUPATIONAL EXPOSURE AND BENIGN NODULAR THYROID DISEASE? [PDF]

open access: yes, 2019
Objective: The prevalence of benign nodular thyroid disease in the general population is high, as shown by various studies, and the diagnosis is eased by the improved diagnostic capacity of the instruments used.
Lo Baido Chiara   +2 more
core   +1 more source

Lithium‐Charged Gold Nanoparticles: A New Powerful Tool for Lithium Delivery and Modulation of Glycogen Synthase Kinase 3 Activity

open access: yesAdvanced Materials, EarlyView.
This study introduces glutathione‐stabilized gold nanoparticles for targeted lithium delivery (LiG‐AuNPs), enabling the controlled modulation of Glycogen Synthase Kinase‐3 (GSK‐3β). These non‐toxic, 2‐nm particles release lithium intracellularly, effectively inhibiting GSK‐3β in the brain without significant plasma lithium alterations.
Antonio Buonerba   +20 more
wiley   +1 more source

A study of serum IgG4 levels in the clinical metamorphosis of autoimmune thyroid disease

open access: yesJournal of Clinical & Translational Endocrinology, 2017
Background: Measurement of serum IgG4 had been suggested to distinguish the unique subtypes of autoimmune thyroid disease (AITD) which demonstrated patterns of fluctuating between hyperthyroidism and hypothyroidism. However, the clinical utility of serum
Yotsapon Thewjitcharoen   +7 more
doaj   +1 more source

Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study [PDF]

open access: yes, 2017
© 2017 Endocrine Society. Background: Soy protein with isoflavones appears to have an adverse effect on thyroid function, but it is not known whether it is the protein or isoflavone component that is deleterious.
Atkin, Stephen L.   +4 more
core   +1 more source

Advanced Materials in Responsible Electronics: Innovations for Sustainability, Health, and Circularity

open access: yesAdvanced Materials Technologies, EarlyView.
Contemporary electronic devices produce significant waste, harming ecosystems. Innovation in design, consumption, materials, and end‐of‐life management is crucial. This review explores advanced materials for sustainable and responsible electronics, highlighting their potential to reduce environmental and health hazards while improving device ...
Rawan Omar   +7 more
wiley   +1 more source

Significant role of 1,25-dihydroxyvitamin D on serum calcium levels after total thyroidectomy: a prospective cohort study

open access: yesFrontiers in Endocrinology
IntroductionAlthough active vitamin D (VD) has been used both preoperatively and postoperatively to prevent hypocalcemia risk in patients undergoing total thyroidectomy, the role of 1,25-dihydroxyvitamin D (1,25(OH)2D) has not been examined.
Hiroyuki Yamashita   +7 more
doaj   +1 more source

Thyroid Antibodies and Thyroiditis [PDF]

open access: yesPostgraduate Medical Journal, 1960
G. A. Smart, S. G. Owen
openaire   +3 more sources

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