Results 61 to 70 of about 1,036,992 (346)

Management Guidelines for Children With Thyroid Nodules and Differentiated Thyroid Cancer

Pediatrics, 2018
Background: Previous guidelines for the management of thyroid nodules and cancers were geared toward adults. Compared with thyroid neoplasms in adults, however, those in the pediatric population exhibit differences in pathophysiology, clinical ...
G. Francis, S. Waguespack, A. Bauer, P. Angelos, S. Benvenga, J. Cerutti, C. Dinauer, J. Hamilton, I. Hay, M. Luster, M. Parisi, M. Rachmiel, G. Thompson, S. Yamashita   +13 more
semanticscholar   +1 more source

Two‐way inhibition of PAX5 transcriptional activity by PAX5::CBFA2T3

FEBS Open Bio, EarlyView.
PAX5::CBFA2T3 (PAX5‐C) is a fusion protein of the B‐cell transcription factor, PAX5, and is found in B‐cell ALL. We propose a putative model of two‐way inhibition of PAX5 transcriptional activity by PAX5‐C. There are two ways of repression by PAX5‐C: DNA‐binding‐dependent way and HDAC‐dependent way, with either being sufficient for the repression. HDAC
Reina Ueno, Aki Terasaki, Yuiko Imai, Yuri Kimura, Yuna Kojima, Misa Irie, Koya Odaira, Mina Noura, Shuichi Okamoto, Takahiko Yasuda, Shinobu Tsuzuki, Hitoshi Kiyoi, Fumihiko Hayakawa   +12 more
wiley   +1 more source

Single inferior parathyroid autotransplantation during total thyroidectomy with bilateral central lymph node dissection for papillary thyroid carcinoma: a retrospective cohort study

World Journal of Surgical Oncology, 2023
Background Management of the inferior parathyroid gland using total thyroidectomy (TT) with central lymph node dissection (CLND) is still controversial.
Zhizhong Dong, Wen Liu, Ying Peng, Xiangxiang Zhan, Yanjun Su, Chang Diao, Ruochuan Cheng   +6 more
doaj   +1 more source

Paroxysmal Dyskinesias Secondary to HHV‐6A Encephalitis: The First Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paroxysmal dyskinesias encompasses a spectrum of conditions marked by intermittent involuntary movements, with paroxysmal kinesigenic dyskinesias being the most common phenotype. Central nervous system infection is a rare cause of paroxysmal dyskinesias.
Zhuoran Wang, Haiting Li, Xiaoping Du, Qiong Wang, Yating Zhang, Huifang Wang   +5 more
wiley   +1 more source

Trends in influenza and pneumococcal vaccine coverage in Thai patients with type 2 diabetes mellitus 2010–2018: Experience from a tertiary diabetes center in Bangkok

Journal of Clinical & Translational Endocrinology, 2020
Trends in influenza and pneumococcal vaccine coverage in Thai patients with type 2 diabetes mellitus 2010–2018: Experience from a tertiary diabetes center in Bangkok. Background: Routine vaccination is an important part of preventive services in treating
Yotsapon Thewjitcharoen, Siriwan Butadej, Areeya Malidaeng, Nalin Yenseung, Soontaree Nakasatien, Nampetch Lekpittaya, Worawit Kittipoom, Sirinate Krittiyawong, Thep Himathongkam   +8 more
doaj  

2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum.

Thyroid, 2011
BACKGROUND Thyroid disease in pregnancy is a common clinical problem. Since the guidelines for the management of these disorders by the American Thyroid Association (ATA) were first published in 2011, significant clinical and scientific advances have ...
E. Alexander, E. Pearce, G. Brent, Rosalind S. Brown, Herbert Chen, C. Dosiou, W. Grobman, P. Laurberg, J. Lazarus, S. Mandel, R. Peeters, Scott A. Sullivan   +11 more
semanticscholar   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu, Hao Zhang, Chao Gao, Qiuhua Yu, Moli Fan, Lin‐Jie Zhang, Haipeng Zhang, Hengri Cong, Yuzhen Wei, Chotima Böttcher, Alexej Verkhratsky, Friedemann Paul, Fu‐Dong Shi, Tian Song   +13 more
wiley   +1 more source

Metal Nanoclusters for Cancer Imaging and Treatment

Advanced Functional Materials, EarlyView.
This review aims to provide a comprehensive summary and discussion of the core–shell design capabilities of metal nanoclusters (NCs) at the atomic level for cancer imaging and treatment. It offers essential insights into the design principles of metal NCs while also encouraging the exploration of other nanomaterials and their potential theranostic ...
Haiguang Zhu, Ziping Wang, Qiaofeng Yao, Ping Zhang, Jianping Xie, Xun Yuan   +5 more
wiley   +1 more source

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

A study of serum IgG4 levels in the clinical metamorphosis of autoimmune thyroid disease

Journal of Clinical & Translational Endocrinology, 2017
Background: Measurement of serum IgG4 had been suggested to distinguish the unique subtypes of autoimmune thyroid disease (AITD) which demonstrated patterns of fluctuating between hyperthyroidism and hypothyroidism. However, the clinical utility of serum
Yotsapon Thewjitcharoen, Sirinate Krittiyawong, Sriurai Porramatikul, Ekgaluck Wanothayaroj, Nampetch Lekpittaya, Jirapat Jeamjiraprasert, Soontaree Nakasatien, Thep Himathongkam   +7 more
doaj   +1 more source