Results 211 to 220 of about 938,886 (254)

NKX2‐1 Downstream Regulatory Structural Variants Explain a Substantial Proportion of Molecular Diagnoses in Patients With Benign Hereditary Chorea

open access: yesMovement Disorders, EarlyView.
Abstract Background NKX2‐1–related disorders (NKX2‐1‐RDs) classically present with a triad of neurological, endocrine, and pulmonary manifestations, including benign hereditary chorea. However, in a fraction of patients, NKX2‐1 coding variants are not detected, and variants outside the NKX2‐1 locus have been reported.
Robin Wijngaard   +33 more
wiley   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

open access: yesObesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter   +14 more
wiley   +1 more source

Metastatic Papillary Thyroid Carcinoma Without Intrathyroidal Primary: Case Report and Literature Review. [PDF]

open access: yesCase Rep Surg
Alsayyari MS   +6 more
europepmc   +1 more source

2025 American Thyroid Association Management Guidelines for Adult Patients With Differentiated Thyroid Cancer: What's New for Surgeons?

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract The American Thyroid Association (ATA) has published an update to the 2015 management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer (DTC). This updated version focuses solely on the management of differentiated thyroid cancer, offering a comprehensive set of guidelines for all stakeholders in the care of ...
Chau Nguyen   +2 more
wiley   +1 more source

The Diagnostic Performance of Afirma Genomic Sequencing Classifier in Black and Hispanic Patients With Indeterminate Thyroid Nodules

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective About 20% of thyroid nodules detected on ultrasound are cytologically indeterminate (Bethesda categories III and IV), but the rate of malignancy of these nodules is less than 36%. The ability of Afirma Genomic Sequencing Classifier (GSC) to further risk‐stratify indeterminate thyroid nodules among Black and Hispanic patients is ...
Peter J. Attia   +5 more
wiley   +1 more source

Ectopic calcitonin-secreting pulmonary neuroendocrine tumor mimicking medullary thyroid carcinoma. [PDF]

open access: yesJCEM Case Rep
Baykal RG   +5 more
europepmc   +1 more source

Clinical Effectiveness of Sialendoscopy in Radioactive Iodine‐induced Sialadenitis: A Systematic Review and Meta‐analysis

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To systematically review and synthesize outcomes following sialendoscopy in patients with salivary gland dysfunction and a history of radioactive iodine (RAI). Data Sources A comprehensive search of Medline, Embase, and Cochrane Library was conducted from database inception through December 26, 2025.
Michal Kulasek   +2 more
wiley   +1 more source

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