Results 221 to 230 of about 938,886 (254)

Improving Voice Outcomes After Transoral Laser Surgery for Early Glottic Cancer: A Systematic Review

open access: yesOtolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To determine which intraoperative and postoperative interventions improve voice outcomes following transoral laser microsurgery (TLM) for early‐stage glottic squamous cell carcinoma (T1‐T2). Data Sources English literature was searched on PubMed, OVID Medline, CINAHL, Embase, and Scopus. Review Methods PRISMA guidelines were followed.
Jamie T. Koscak   +8 more
wiley   +1 more source

Comprehensive genomic profiling of mucosal melanoma reveals novel fusion transcripts and dysregulation of cell‐cycle, MAPK, and PI3K pathways

open access: yesThe Journal of Pathology, EarlyView.
Abstract Mucosal melanomas (MMs) are rare, aggressive cancers with poor outcomes and limited response to standard therapies. A significant knowledge gap exists regarding their genomic landscape and corresponding druggable targets. This study explores this issue through a multi‐omic analysis, including whole exome‐, RNA‐, and targeted sequencing, of ...
Matilde Monti   +21 more
wiley   +1 more source

Network based approach identifies miR‐145‐3p as a central regulatory hub associated to the progression from localized to metastatic medullary thyroid carcinoma

open access: yesThe Journal of Pathology, EarlyView.
Abstract Medullary thyroid carcinoma (MTC) is a neuroendocrine tumor originating from calcitonin producing C‐cells and accounts for 1–5% of thyroid cancers. Total thyroidectomy is curative in localized disease (N0), whereas lymph node metastases (N1) are associated with poorer prognosis.
Anna Citarella   +24 more
wiley   +1 more source

Proteomic analysis of papillary thyroid carcinoma in the context of Hashimoto's thyroiditis. [PDF]

open access: yesSci Rep
Zhou H   +8 more
europepmc   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

open access: yesPrecision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang   +7 more
wiley   +1 more source

Validation of the 2025 ATA risk stratification system in a cohort of patients with papillary thyroid carcinoma.

open access: yesJ Clin Endocrinol Metab
Moneta C   +9 more
europepmc   +1 more source

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