Results 91 to 100 of about 527,362 (224)

Therapeutic strategies to target the receptor tyrosine kinase AXL in thyroid cancer

, 2012
The AXL receptor tyrosine kinase is overexpressed and active in various cancer types including thyroid carcinoma, and several preclinical studies suggest that targeting AXL is an effective therapeutical strategy in AXL-positive cancers.
MELILLO, ROSA MARINA, GnanaPrakasam Krisnamoorthy, VISCIANO, CARLA, CARLOMAGNO, Francesca, LIOTTI, FEDERICA, GUIDA, TERESA   +5 more
core  

The 5T Paradox of Triclosan: From Toiletries to Toxic Trash, a Growing Threat to Humanity

Environmental Toxicology, EarlyView.
ABSTRACT Triclosan (TCS) persists as a contaminant of concern in the Anthropocene, despite regulatory actions. Environmental dissemination continues through wastewater effluents, biosolid application, and improper disposal practices. This narrative review synthesizes current evidence regarding triclosan's environmental fate, transformation pathways ...
Temitope Aribigbola, Mauro Ricardo Souza da Luz, Sunday Amos Onikanni, Marjorie Dardis Murucci, Oluwatosin Stella Olayinka, Rodrigo Soares Fortunato, Rômulo Sperduto Dezonne, Omolola Esther Amos, Sara Gemini Piperni, Denise Pires de Carvalho, Leandro Miranda‐Alves   +10 more
wiley   +1 more source

Synchronous Hurthle Cell Carcinoma and Papillary Carcinoma in a Patient with Hashimoto’s Thyroiditis: A Rare Case Report

Middle East Journal of Cancer, 2014
Hashimoto’s thyroiditis, the most common autoimmune thyroid disease, is due to destruction of the thyroid gland by autoantibodies. Various types of thyroid malignancies may arise in Hashimoto’s thyroiditis.
Narayanan O. Navya, Kanapilly F. Magdalene , Gopinath P. Satheesh   +2 more
doaj  

Hashimoto’s thyroiditis presenting as cerebellar stroke

Asian Journal of Medical Sciences, 2016
Hashimoto’s thyroiditis (HT) or autoimmune hypothyroidism is the most common form of primary hypothyroidism, characterized by lymphocytic infiltration of the thyroid gland thereby leading to its destruction. It is more common in females.
Robin George Manappallil
doaj   +1 more source

Evaluation of thyroglobulin autoantibodies in dogs at the time of diagnosis of hypoadrenocorticism and during treatment

Veterinary Record, EarlyView.
Abstract Background Autoimmune thyroiditis (AIT) may occur more frequently in dogs with hypoadrenocorticism (HA) than previously recognised. The objective of this study was to determine the presence of thyroglobulin autoantibodies (TgAAs) in dogs with HA.
Christin Emming, Sina Strey, Ina Leiter, Reinhard Mischke, Holger Volk, Marion Schmicke, Johanna Rieder   +6 more
wiley   +1 more source

Ultrasound-targeted microbubble destruction enhances RSL3-induced ferroptosis in anaplastic thyroid carcinoma

iScience
Summary: Anaplastic thyroid carcinoma (ATC) is a highly aggressive malignancy with limited effective therapies. Ferroptosis, a form of programmed cell death, is closely associated with thyroid cancer prognosis and represents a potential therapeutic ...
Xinyao Liu, Liangkai Wang, Xinyi Liu, Yang Du, Bo Zhang   +4 more
doaj   +1 more source

Interventional oncology in children: Where are we now?

Journal of Medical Imaging and Radiation Oncology, EarlyView.
Abstract Paediatric Interventional Oncology (IO) lags behind adult IO due to a scarcity of specific outcome data. The suboptimal way to evolve this field is relying heavily on adult experiences. The distinct tumour types prevalent in children, such as extracranial germ cell tumours, sarcomas, and neuroblastoma, differ strongly from those found in ...
Premal Amrishkumar Patel, Fernando Gómez Muñoz   +1 more
wiley   +1 more source

CONDITION OF THE ERYTHROID PART OF BLOOD SYSTEM AT STRESSED ANIMALS WITH HYPOTHYREOSIS

Acta Biomedica Scientifica, 2012
Hypothyreosis, caused by introduction of mercazolil, leads to reduction of production of thyroid hormones, destabilization of membranes and. acceleration of erythrocytes destruction, activation of erythropoiesis, development of macroerythrocytosis in ...
D. V. Garmayeva, L. S. Vasilyeva, O. A. Makarova, N. G. Makarova   +3 more
doaj  

Supplementation with active vitamin D3 ameliorates experimental autoimmune thyroiditis in mice by modulating the differentiation and functionality of intrathyroidal T-cell subsets

Frontiers in Immunology
ObjectivePeople with Hashimoto’s thyroiditis (HT) often have low vitamin D3 concentrations. Some research has suggested that vitamin D3 supplementation reduces thyroid inflammation, but this remains controversial.MethodsEAT was induced in female NOD ...
Chun-Mei Wang, Ying-Jie Chen, Bo-Cheng Yang, Jia-Wen Yang, Wei Wang, Yang Zeng, Jun Jiang   +6 more
doaj   +1 more source

The Anthropocene and the End of Nuclear Disaster: Normalizing the Fukushima Nuclear Accident

American Anthropologist, EarlyView.
ABSTRACT This article places the concept of disaster in critical dialogue with that of the Anthropocene, which introduces new imaginaries that negatively affect the governance of crises like nuclear accidents. I argue that tropes surrounding the Anthropocene can depict certain events as apocalyptic calamities while also portraying other events as mere “
Maxime Polleri
wiley   +1 more source