Results 111 to 120 of about 527,362 (224)
Charting the course of Sjögren's disease: A historical analysis of scientific progress
European Journal of Oral Sciences, EarlyView.Abstract Sjögren's disease (SjD) bears the name of the Swedish ophthalmologist Henrik Sjögren. His 1933 doctoral thesis on keratoconjunctivitis sicca ignited interest, yet much remains under debate. SjD is an autoimmune disorder that primarily affects the exocrine glands, particularly the salivary and lacrimal glands, leading to a dryness of the eyes ...
Diego Ustárroz Cantali +3 more
wiley +1 more source
Advanced ScienceAutoimmune thyroiditis (AIT) is characterized by extensive lymphocytic infiltration and progressive destruction of thyroid follicular cells (TFCs), yet the molecular mechanisms underlying persistent thyroid injury remain poorly defined.
Qingyi Hu +7 more
doaj +1 more source
From hepatic to hematopoietic: LRH‐1's expanding cellular repertoire to the immune system
The FEBS Journal, EarlyView.The nuclear receptor LRH‐1 is a well‐characterized regulator of endodermal tissue. Yet, increasing evidence indicates that LRH‐1, although expressed at low levels, is also a critical regulator of the hematopoietic system. LRH‐1 regulates the immune system by contributing to immune cell‐specific functions.
Lukas Meisinger +3 more
wiley +1 more source
Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis
International Journal of Dermatology, EarlyView.Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller +11 more
wiley +1 more source
Proteomic and Postproteomic Characterization of Keratan Sulfate-Glycanated Isoforms of Thyroglobulin and Transferrin Uniquely Elaborated by Papillary Thyroid Carcinomas. [PDF]
, 2003 Previous studies have suggested that surface components of papillary thyroid carcinoma (PTC) cells may be aberrantly glycanated, but the precise nature of these molecules has not been unveiled nor documented to be of clinical relevance.
Goletz, Steffen +11 more
core +1 more source
Combining Transfer of TTF-1 and Pax-8 Gene: a Potential Strategy to Promote Radioiodine Therapy of Thyroid Carcinoma [PDF]
, 2011 Cotransfer of TTF-1 and Pax-8 gene to tumor cells, resulting in the reexpression of iodide metabolism-associated proteins, such as sodium iodide symporter (NIS), thyroglobulin (Tg), thyroperoxidase (TPO), offers the possibility of radioiodine therapy to ...
Da Mu +4 more
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Journal of Agrarian Change, EarlyView.ABSTRACT What do pesticide companies do to keep their products on the market despite strong societal and scientific critiques of their environmental and health risks? This paper examines the herbicide paraquat, one of the most controversial pesticides, from the early 1960s to the present.
Kees Jansen
wiley +1 more source
Why do national IDD control programmes fail : case studies from Indo-China
, 2014 Iodine is a trace element and is responsible for the synthesis of thyroid hormones that are critical for brain development especially in the foetal and early childhood development1.
Ma, Gary (R17095)
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Imaging and Laboratory Approach to Thyroid Diseases
, 2020 Thyroid function tests need for estimating functional activity of thyroid gland and autoantibodies support for diagnosis of thyroid dysfunction. FNA and molecular testing are used as confirmation examination for thyroid malignancy.
Michihiro, Mayu
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