Results 41 to 50 of about 442,297 (356)

Screening of endocrine organ-specific humoral autoimmunity in 47,XXY Klinefelter's syndrome reveals a significant increase in diabetes-specific immunoreactivity in comparison with healthy control men. [PDF]

, 2015
The aim of this study was to evaluate the frequency of humoral endocrine organ-specific autoimmunity in 47,XXY Klinefelter’s syndrome (KS) by investigating the autoantibody profile specific to type 1 diabetes (T1DM), Addison’s disease (AD), Hashimoto ...
ANZUINI, Antonella, GIANFRILLI, DANIELE, GRANATO, SIMONA, LENZI, Andrea, PANIMOLLE, FRANCESCA, RADICIONI, Antonio, Semeraro, A, TIBERTI, Claudio   +7 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Inflammation related proteins and PLCG1 may contribute to papillary thyroid carcinoma risk through a potential regulatory axis

Discover Oncology
Background Papillary thyroid carcinoma (PTC) is usually indolent, but a subset of patients shows aggressive behavior. Understanding protein-level mechanisms is essential for identifying new therapeutic targets. Materials and methods We integrated protein
Shi-Qi Wang, Miao Yang, De-Wei Rao, Yan-Jun Su, Ruo-Chuan Cheng   +4 more
doaj   +1 more source

Peptide receptor radionuclide therapy in patients with medullary thyroid carcinoma: predictors and pitfalls

BMC Cancer, 2019
Background For progressive metastatic medullary thyroid carcinoma (MTC), the available treatment options with tyrosine kinase inhibitors result in grade 3–4 adverse events in a large number of patients. Peptide Receptor Radionuclide Therapy (PRRT), which
Carolien M. Beukhof, Tessa Brabander, Francien H. van Nederveen, Marie-Louise F. van Velthuysen, Yolanda B. de Rijke, Leo J. Hofland, Gaston J. H. Franssen, Lideke A. C. Fröberg, Boen L. R. Kam, W. Edward Visser, Wouter W. de Herder, Robin P. Peeters   +11 more
doaj   +1 more source

Prevalence of nodular goiter in patients with breast diseases [PDF]

Journal of Clinical and Investigative Surgery, 2020
Introduction. Various studies have reported conflicting results regarding the relationship between breast and thyroid diseases. The exact pathogenesis behind this association is not clear.
Yalagachin, Gurushantappa, Lakshmikantha, Nishanth, Mashal, Sanjay B.   +2 more
doaj   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Concurrent papillary thyroid cancer and parathyroid adenoma as a rare condition: A case report [PDF]

, 2012
Although the pathological relationship between parathyroid and thyroid diseases is common, an association between parathyroid adenoma and thyroid cancer is rare.
Assadi, M., Farrokhi, S., Jallalat, S., Javadi, H., Mogharrabi, M., Moshtaghi, D., Nabipour, I., Riazi, A., Semnani, S.   +8 more
core   +1 more source

Galectin-3. One molecule for an alphabet of diseases, from A to Z [PDF]

, 2018
Galectin-3 (Gal-3) regulates basic cellular functions such as cell–cell and cell–matrix interactions, growth, proliferation, differentiation, and inflammation.
Bellotti, Carlo, De Francesco, Gian Paolo, Lavra, Luca, Magi, Fiorenza, Morgante, Alessandra, Ricci, Alberto, Salehi, Leila B., Sciacchitano, Salvatore, Ulivieri, Alessandra   +8 more
core   +2 more sources

Association between lymphocyte to high-density lipoprotein cholesterol ratio and insulin resistance and metabolic syndrome in US adults: results from NHANES 2007–2018

Lipids in Health and Disease
Background Insulin resistance (IR) and metabolic syndrome (MetS) are significant global health challenges that increase the risk of various chronic diseases.
Junwei Guo, Kelibinuer Mutailipu, Xin Wen, Jiajing Yin, Hui You, Shen Qu, Haibing Chen, Le Bu   +7 more
doaj   +1 more source

Videos on YouTube, Bilibili, TikTok as sources of medical information on Hashimoto’s thyroiditis

Frontiers in Public Health
IntroductionHashimoto’s thyroiditis (HT), a common autoimmune thyroid disorder, is widely discussed on video-sharing platforms. However, user-generated content about HT lacks systematic scientific validation.
Shiqi Wang, Siyu Jia, Yanjun Su, Ruochuan Cheng   +3 more
doaj   +1 more source