Results 41 to 50 of about 374,853 (289)

Association between lymphocyte to high-density lipoprotein cholesterol ratio and insulin resistance and metabolic syndrome in US adults: results from NHANES 2007–2018

open access: yesLipids in Health and Disease
Background Insulin resistance (IR) and metabolic syndrome (MetS) are significant global health challenges that increase the risk of various chronic diseases.
Junwei Guo   +7 more
doaj   +1 more source

Thyroid Diseases

open access: yesSri Lanka Journal of Diabetes Endocrinology and Metabolism, 2012
Sri Lanka Journal of Diabetes, Endocrinology and Metabolism 2012; 2: S1-S20 DOI: http://dx.doi.org/10.4038/sjdem.v2i2 ...
Noel Somasundaram   +22 more
doaj   +1 more source

Safety and immunogenicity of the third (booster) dose of inactivated and recombinant protein SARS-CoV-2 vaccine for patients with endocrine-related cancer

open access: yesFrontiers in Public Health, 2023
BackgroundOur study aimed to evaluate the safety and immunogenicity of the third (booster) dose of the COVID-19 vaccine for patients with endocrine-related cancers.MethodsThis observational study involved 94 breast cancer patients, 92 thyroid cancer ...
Shanshan Han   +10 more
doaj   +1 more source

Correction Of Iodine Deficiency States And Dynamic Modeling Of Positive Dynamics Of Indicators Of Thyroid Functions By Supplementation [PDF]

open access: yes, 2018
The problem of iodine deficiency diseases (IDD) is recognized as relevant due to the significant prevalence of iodine deficiency among the population of many countries of the world, an increase in the incidence of diseases with a wide range of clinical ...
Devinyak, O. (Oleg)   +3 more
core   +2 more sources

Landscape of BRAF transcript variants in human cancer

open access: yesMolecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda   +5 more
wiley   +1 more source

Molecular mechanism of thyroxine transport by monocarboxylate transporters

open access: yesNature Communications
Thyroid hormones (the common name for prohormone thyroxine and the bioactive form triiodothyronine) control major developmental and metabolic processes.
Matteo Tassinari   +10 more
doaj   +1 more source

Thyroid Autoimmunity as a Window to Autoimmunity: An Explanation for Sex Differences in the Prevalence of Thyroid Autoimmunity [PDF]

open access: yes, 2015
Autoimmune thyroid diseases (AITDs), predominately Graves׳ disease and Hashimoto׳s thyroiditis, comprise the most common autoimmune diseases in humans.
Merrill, Stephen, Mu, Ying
core   +1 more source

Antigen receptor variable region repertoires expressed by T cells infiltrating thyroid, retroorbital, and pretibial tissue in Graves' disease [PDF]

open access: yes, 1996
To date, it has remained unclear whether T cells infiltrating thyroid, retroorbital, and pretibial tissue of patients with Graves' ophthalmopathy and pretibial dermopathy represent a primary immune response that is directed against certain antigenic ...
Heufelder, Armin E.   +2 more
core   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Ameliorative effect and mechanism of ursodeoxycholic acid on hydrogen peroxide-induced hepatocyte injury

open access: yesScientific Reports
To assess the ameliorative effect of ursodeoxycholic acid (UDCA) on hydrogen peroxide (H2O2)-induced hepatocyte injury. In our in vivo experiments, we modelled hyperlipidemia in ApoE−/− mice subjected to a 3-month high-fat diet and found that HE staining
Xueqin Wang   +4 more
doaj   +1 more source

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