Results 51 to 60 of about 442,297 (356)

A novel signature to predict thyroid cancer prognosis and immune landscape using immune-related LncRNA pairs

BMC Medical Genomics, 2022
Background Thyroid cancer (TC) is the most common endocrine malignancy worldwide. The incidence of TC is high and increasing worldwide due to continuous improvements in diagnostic technology.
Bo Song, Lijun Tian, Fan Zhang, Zheyu Lin, Boshen Gong, Tingting Liu, Weiping Teng   +6 more
doaj   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Turner syndrome and associated problems in turkish children: A multicenter study [PDF]

, 2015
Objective: Turner syndrome (TS) is a chromosomal disorder caused by complete or partial X chromosome monosomy that manifests various clinical features depending on the karyotype and on the genetic background of affected girls.
Abacı, A., Abalı, S., Adal, E., Akın, L., Akıncı, A., Akyürek, N., Andıran, N., Anık, A., Atabek, M.E., Ataş, A., Aydın, B.K., Açıkel, C., Baş, F., Baş, S., Baş, V.N., Bereket, A., Binay, Ç., Bolu, S., Bondy, C., Bulan, K., Büyükinan, M., Can, H.D., Cinaz, P., Darcan, Ş., Darendeliler, F., Demir, K., Demirbilek, H., Demirel, F., Doğan, D., Doğan, M., Döneray, H., Dündar, B., Eklioğlu, B.S., Emeksiz, H.C., Ercan, O., Eren, E., Ersoy, B., Evliyaoğlu, O., Fidancı, K., Gökşen, D., Gül, D., Gürbüz, F., Hatun, Ş., Kaba, S., Kara, C., Karagüzel, G., Keskin, M., Kızılay, D., Orbak, Z., Pirgon, Ö., Polat, A., Poyrazoğlu, Ş., Sarı, E., Sağlam, H., Tarım, Ö., Tepe, D., Topaloğlu, A.K., Turan, S., Yeşilkaya, E., Yüksel, B., Çakır, E.D., Çatlı, G., Çelik, N., Çizmecioğlu, F., Ökten, A., Önal, H., Özbek, M.N., Özen, S., Özgen, T., Özhan, Bayram, Özkan, B., Ünüvar, T., Şen, Y., Şimşek, E.   +73 more
core   +1 more source

Molecular mechanism of thyroxine transport by monocarboxylate transporters

Nature Communications
Thyroid hormones (the common name for prohormone thyroxine and the bioactive form triiodothyronine) control major developmental and metabolic processes.
Matteo Tassinari, Giorgia Tanzi, Francesco Maggiore, Stefan Groeneweg, Ferdy S. van Geest, Matthijs E. T. Freund, Christiaan J. Stavast, Irene Boniardi, Sebastiano Pasqualato, W. Edward Visser, Francesca Coscia   +10 more
doaj   +1 more source

Pathological damage of thyroidopathy and the prevalence of thyroid diseases in children of the Perm region

Acta Biomedica Scientifica, 2022
Relevance. Thyroid diseases in children and adolescents rank first in the structure of endocrine pathology. An issue related to comparability of data on prevalence obtained with different procedures is vital given the necessity to intensify activities ...
I. E. Shtina, S. L. Valina, Yu. A. Ivashova, O. Yu. Ustinova, D. A. Eisfeld   +4 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Subclinical Thyroid Disease [PDF]

Mayo Clinic Proceedings, 2001
The term subclinical thyroid disease is used to describe asymptomatic thyroid abnormalities found on imaging studies or laboratory tests. Thyroid nodules not palpable on physical examination but detected on imaging studies performed for other purposes are called incidentalomas.
openaire   +2 more sources

Indonesian Clinical Practice Guidelines for Hyperthyroidism

Journal of the ASEAN Federation of Endocrine Societies, 2014
Hyperthyroidism remains as one of the major thyroid disorders in Indonesia.The Indonesian Task Force on Thyroid Diseases determined that hyperthyroidism represents a priority area in need of updated evidence-based practice guidelines.The aim of the ...
The Indonesian Society of Endocrinology Task Force on Thyroid Diseases
doaj  

Ameliorative effect and mechanism of ursodeoxycholic acid on hydrogen peroxide-induced hepatocyte injury

Scientific Reports
To assess the ameliorative effect of ursodeoxycholic acid (UDCA) on hydrogen peroxide (H2O2)-induced hepatocyte injury. In our in vivo experiments, we modelled hyperlipidemia in ApoE−/− mice subjected to a 3-month high-fat diet and found that HE staining
Xueqin Wang, Guangxi Liang, Yang Zhou, Banggao Ni, Xiangyu Zhou   +4 more
doaj   +1 more source

Estimating global prevalence of gallbladder stones in general population from 2000 to 2024: systematic review and meta-analysis

Annals of Medicine
Background Gallbladder stones (GS), is one of the most common and costly of all the gastrointestinal diseases. However, global prevalence estimates of GS remain heterogeneous due to methodological variations across studies, and consensus on risk factor ...
Qingyang Ning, Fen Liu, Yiqiao Fang, Xixi Zhu, Jiaye Liu, Zhihui Li   +5 more
doaj   +1 more source