Results 51 to 60 of about 374,853 (289)

Comparison of polybrominated diphenyl ethers (PBDEs) and polychlorinated biphenyls (PCBs) in the serum of hypothyroxinemic and euthyroid dogs. [PDF]

, 2017
ObjectiveTo determine the profile of 14 polybrominated diphenyl ethers (PBDEs) and 23 polychlorinated biphenyls (PCBs) in serum of domestic canines and whether this was predictive of thyroid hormone status.SamplesSerum samples were collected from 51 ...
Kass, Philip, Lau, Grace, Puschner, Birgit, Walter, Kyla   +3 more
core   +3 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

Molecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim, Sungwoo Bae, Jaeyong Choi, Sun‐Wha Im, Bukyoung Cha, Gyeongseo Jung, Sun Wook Cho, Eul‐Ju Seo, Young Ah Lee, Jin Chul Paeng, Young Joo Park, Jong‐Il Kim   +11 more
wiley   +1 more source

Indonesian Clinical Practice Guidelines for Hyperthyroidism

Journal of the ASEAN Federation of Endocrine Societies, 2014
Hyperthyroidism remains as one of the major thyroid disorders in Indonesia.The Indonesian Task Force on Thyroid Diseases determined that hyperthyroidism represents a priority area in need of updated evidence-based practice guidelines.The aim of the ...
The Indonesian Society of Endocrinology Task Force on Thyroid Diseases
doaj  

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

A possible role for selenoprotein glutathione peroxidase (GPx1) and thioredoxin reductases (TrxR1) in thyroid cancer. Our experience in thyroid surgery [PDF]

, 2018
Background: Oxidative stress is responsible for some alterations in the chemical structure and, consequently, in the function of proteins, lipids, and DNA.
DE LUCA, Alessandro, Frezzotti, Francesca, Giacomelli, Laura, Graves, Claire Elizabeth, Metere, Alessio, Pietraforte, Donatella, Vergine, Massimo   +6 more
core   +2 more sources

Impact of contraception and IVF hormones on metabolic, endocrine, and inflammatory status [PDF]

, 2020
Assisted reproductive technologies (ART) represent commonly utilized management strategies for infertility with multifactorial causes (including genetically predisposed diseases). Amongst ART, in vitro fertilization (IVF) is the most popular.
Barber, Thomas M., Coussa, Ayla, Hassan, Hayder   +2 more
core   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Integrative Analyses of Mitophagy-Related Genes and Mechanisms Associated with Type 2 Diabetes in Muscle Tissue

Current Issues in Molecular Biology
Type 2 diabetes (T2D) represents the most prevalent metabolic condition that is primarily distinguished by a range of metabolic imbalances, including hyperglycemia, hyperlipidemia, and insulin resistance (IR). Currently, mitophagy has become increasingly
Wangjia Mao, Guannan Zong, Yuan Gao, Shen Qu, Xiaoyun Cheng   +4 more
doaj   +1 more source

Pathological damage of thyroidopathy and the prevalence of thyroid diseases in children of the Perm region

Acta Biomedica Scientifica, 2022
Relevance. Thyroid diseases in children and adolescents rank first in the structure of endocrine pathology. An issue related to comparability of data on prevalence obtained with different procedures is vital given the necessity to intensify activities ...
I. E. Shtina, S. L. Valina, Yu. A. Ivashova, O. Yu. Ustinova, D. A. Eisfeld   +4 more
doaj   +1 more source