Results 51 to 60 of about 155,166 (304)

Evaluation of Thyroid Dysfunction in Type 2 DM in Duhok Governorate

Advanced Medical Journal, 2022
Background and Objectives Thyroid diseases and Diabetes are the most common endocrinal disorders seen in clinical practice. As a result, it is common for an individual to be affected by both thyroid diseases and diabetes. Most studies show an increased
Sefar Mohamad Al Haj , Bayar Ahmed Qasim   +1 more
doaj   +1 more source

Prevalence of Thyroid Dysfunction Among Postmenopausal Women in Baghdad Medical City [PDF]

Background: One of the most frequent endocrine abnormalities and changes in females, especially during the postmenopausal period, is thyroid dysfunction.
Hayder AL-MOMEN, Sajad Adel Abdul HUSSEIN, Harith Abdul Rahman IBRAHIM, Shaymaa Kadhim JASIM, Abdullah Ahmed MAHDI   +4 more
core   +1 more source

Identifying and treating subclinical thyroid dysfunction in pregnancy: emerging controversies [PDF]

, 2018
Thyroid hormones are essential for an adequate growth and development of the fetus. In addition to the classical association between maternal hypothyroidism and neurological impairment in the progeny, other adverse reproductive events have been ...
Inés Velasco, Velasco, Inés, Taylor, Peter; id_orcid, Taylor, Peter, Peter Taylor   +4 more
core   +1 more source

Functional Mapping of Neurodevelopmental Disease Pathways to Key Neurodevelopmental Processes Represented in the Developmental Neurotoxicity In Vitro Testing Battery

Advanced Science, EarlyView.
Human‐relevant methods are essential for modern chemical safety assessment. This study helps define the capabilities and boundaries of an in vitro testing battery for developmental neurotoxicity by exploring its biological applicability domain. By linking neurodevelopmental disease‐related pathways to key neurodevelopmental processes, the work enhances
Eliska Kuchovska, Kristina Bartmann, Georgea Raad, Mats Schade, Luiz Ladeira, Arif Dönmez, Jördis Klose, Nicolai Görts, Denis Polozij, Lynn‐Christin Saborowski, Farina Bendt, Bernard Staumont, Liesbet Geris, Katharina Koch, Ellen Fritsche   +14 more
wiley   +1 more source

Thyroid dysfunction and immune checkpoint inhibitor outcomes.

, 2020
Background: Immune checkpoint inhibitors (ICI) frequently cause thyroid dysfunction. We performed a longitudinal analysis of thyroid function tests in a large, single-center cohort of patients with multiple cancer types receiving ICI.
Ali, Sadia, Xie, Yang, Gerber, David E, Cai, Jennifer, Lu, Rong, Xie, Donglu, von Itzstein, Mitchell S   +6 more
core   +1 more source

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

Prevalence of thyroid dysfunction in highly active antiretroviral therapy -Exposed people living with human immunodeficiency virus

Thyroid Research
Background The incidence of thyroid dysfunction is high in HIV patients, contributing to the high mortality and morbidity associated with HIV. Objectives This study focused on evaluating the prevalence of thyroid dysfunction and associated factors among ...
Asma A. Adan, Redemtor A. Ojuang, Steven G. Nyanjom, Edward K. Maina   +3 more
doaj   +1 more source

Thyroid dysfunction and anemia in a large population-based study. [PDF]

, 2016
OBJECTIVE AND BACKGROUND Anemia and thyroid dysfunction are common and often co-occur. Current guidelines recommend the assessment of thyroid function in the work-up of anemia, although evidence on this association is scarce. PATIENTS AND METHODS
Collet, Tinh-Hai, Collet, T.H., Angelillo-Scherrer, A., den Elzen, W.P., Coslovsky, M., Luben, R., Coslovsky, Michael, Aujesky, Drahomir, Khaw, Kay-Tee, Baumgartner, Christine, Angelillo-Scherrer, Anne, Aujesky, D., den Elzen, Wendy P. J., Rodondi, Nicolas, Aubert, Carole E., den Elzen, Wendy P J, Khaw, K.T., Aubert, C.E., M'Rabet-Bensalah, Khadija, Luben, Robert, Aubert, Carole E, M'Rabet-Bensalah, K., M'rabet Bensalah, Khadija, Rodondi, N., Elzen, W.P.J. den, Baumgartner, C.   +25 more
core   +1 more source

BIN1 and ALDH1B1 Deficiency in Colonic Smooth Muscle Drives Mitochondrial Dysfunction and Fibrosis in Slow‐Transit Constipation

Advanced Science, EarlyView.
Slow‐transit constipation (STC) is a disabling motility disorder with unclear smooth‐muscle mechanisms. Spatial proteomic analysis of STC patient colon reveals both the central pathogenic role of smooth muscle cells (SMCs) in STC and novel regulators of intestinal motility, BIN1 and ALDH1B1.
Jianbo Liu, Hao Zhang, Wenhao Qiao, Ran Liu, Jie Sun, Xiaopei Li, Qin Li, Dongbo Zhao, Dawei Chen, Jingxin Li, Shuxiao Dong   +10 more
wiley   +1 more source

Review of the risks and/or benefits of thyroxine treatment in ‘mild’ subclinical hypothyroidism [PDF]

, 2013
Subclinical hypothyroidism (SCH) is a form of mild thyroid failure and is a commonly encountered condition in clinical practice. It denotes the presence of a raised serum thyroid stimulating hormone (TSH) and normal serum free thyroid hormone ...
Agius, Rachel
core