Results 51 to 60 of about 230,472 (304)

Impact of thyroid immune-related adverse events on clinical outcomes in non-small cell lung cancer (NSCLC) patients treated with checkpoint inhibitor therapy: A single center study

Biomolecules & Biomedicine
Immune checkpoint inhibitors (ICIs) have transformed the treatment landscape for non-small cell lung carcinoma (NSCLC) but are associated with immune-related adverse events (irAEs), including thyroid dysfunction.
Šejla Cerić, Timur Cerić, Emir Sokolović, Jasmina Dalač, Dragana Miletić, Inga Marijanović, Layan Mattar, Amina Aljić, Selma Agić-Bilalagić, Amera Šadija, Miran Hadžiahmetović, Semir Bešlija   +11 more
doaj   +1 more source

Evaluation of Thyroid Dysfunction in Type 2 DM in Duhok Governorate

Advanced Medical Journal, 2022
Background and Objectives Thyroid diseases and Diabetes are the most common endocrinal disorders seen in clinical practice. As a result, it is common for an individual to be affected by both thyroid diseases and diabetes. Most studies show an increased
Sefar Mohamad Al Haj , Bayar Ahmed Qasim   +1 more
doaj   +1 more source

Are fluoride levels in drinking water associated with hypothyroidism prevalence in England? A large observational study of GP practice data and fluoride levels in drinking water [PDF]

, 2015
Background While previous research has suggested that there is an association between fluoride ingestion and the incidence of hypothyroidism, few population level studies have been undertaken.
Bath, Chana, Cooper, D Lowery, Day, European Commission, Feltman, Flynn, Galletti, Gillam, Harrison, Jooste, Klein, Larsen, Lee, National Research Council (NRC), Peckham, S Peckham, S Spencer, Vanderpump, Vanderpump, Warren, Wilson   +22 more
core   +1 more source

Small Extracellular Vesicles from Neural Cells: Physiological and Pathological Roles, and Potential in Neurodegenerative Therapy

Advanced Healthcare Materials, EarlyView.
Neural cell–derived small extracellular vesicles (sEVs) are emerging as pivotal mediators in neurodegenerative diseases, exerting both pathogenic and therapeutic functions. This review synthesizes current evidence on how sEVs from distinct neural cell types regulate neurodegeneration, neuroprotection, biomarker discovery, and targeted drug delivery ...
Muhammad Waqas Salim, Wei Zhang, Lyndsey Collins‐Praino, Yuling Wang, Andrew Care   +4 more
wiley   +1 more source

Interplay between cardiovascular and thyroid dysfunctions: A review of clinical implications and management strategies

Endocrine Regulations, 2022
Cardiovascular diseases (CVD) and thyroid dysfunction are two of the most prevailing disorders in the world that are closely interlinked. Actions of thyroid hormones are mediated via thyroid receptors present in the myocardium and the vascular tissue ...
Debmalya Sanyal, Saumitra Ray, Singh Malhi Harshveer   +2 more
doaj   +1 more source

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Cumulative Burden of Morbidity Among Testicular Cancer Survivors After Standard Cisplatin-Based Chemotherapy: A Multi-Institutional Study [PDF]

, 2018
Purpose In this multicenter study, we evaluated the cumulative burden of morbidity (CBM) among > 1,200 testicular cancer survivors and applied factor analysis to determine the co-occurrence of adverse health outcomes (AHOs).
AnnaLynn M. Williams, Christian Kollmannsberger, Chunkit Fung, Clair Beard, Darren R. Feldman, David J. Vaughn, Deepak M. Sahasrabudhe, Howard D. Sesso, Jeri Kim, Lawrence H. Einhorn, Lois B. Travis, Mohammad I. Abu Zaid, null null, Patrick O. Monahan, Robert A. Huddart, Robert J. Hamilton, Ryan Cook, Sarah L. Kerns, Shirin Ardeshir-Rouhani-Fard, Sophie D. Fossa, Timothy E. Stump   +20 more
core   +1 more source

Nivolumab-induced thyroid dysfunction [PDF]

Japanese Journal of Clinical Oncology, 2016
Nivolumab (ONO-4538) is an anti-programmed death-1 specific monoclonal antibody, which has become a standard treatment for metastatic malignant melanoma. Nivolumab induces autoimmune adverse events, defined as immune-related adverse events. Herein, we report a case of nivolumab-induced thyroid dysfunction in the clinical setting. Fourteen patients were
Ryota, Tanaka, Yasuhiro, Fujisawa, Hiroshi, Maruyama, Yasuhiro, Nakamura, Koji, Yoshino, Mikio, Ohtsuka, Manabu, Fujimoto   +6 more
openaire   +2 more sources

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Prevalence of thyroid dysfunction in highly active antiretroviral therapy -Exposed people living with human immunodeficiency virus

Thyroid Research
Background The incidence of thyroid dysfunction is high in HIV patients, contributing to the high mortality and morbidity associated with HIV. Objectives This study focused on evaluating the prevalence of thyroid dysfunction and associated factors among ...
Asma A. Adan, Redemtor A. Ojuang, Steven G. Nyanjom, Edward K. Maina   +3 more
doaj   +1 more source