Results 71 to 80 of about 155,166 (304)

Amiodarone-induced thyroid dysfunction [PDF]

, 2022
Introduction. It has been found that amiodarone can cause a number of side effects, including thyroid dysfunction with an incidence of 1-27%. The incidence in the Republic of Moldova increased from 2% to 13,6% which imposed the need to analyze the ...
Gorița, Adriana
core  

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Risk-Based Screening for Thyroid Dysfunction during Pregnancy

Journal of Pregnancy, 2013
Objective. We conducted the study to see the incidence of thyroid dysfunction in women with obstetrical high-risk factors. Methods. We retrospectively reviewed medical charts of high-risk pregnant women who had examination for thyroid function during ...
Masanao Ohashi, Seishi Furukawa, Kaori Michikata, Katsuhide Kai, Hiroshi Sameshima, Tsuyomu Ikenoue   +5 more
doaj   +1 more source

Thyroid disorders and diabetes mellitus

, 2011
Studies have found that diabetes and thyroid disorders tend to coexist in patients. Both conditions involve a dysfunction of the endocrine system. Thyroid disorders can have a major impact on glucose control, and untreated thyroid disorders affect the ...
Azar S.T., Hage M., Zantout M.S.
core   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan, Qian Zheng, Deng Liu, Ruichao Nie, Menglin Yao, Xiaolong Tang, Renjie Xu, Jinghong Xian, Wenjun Meng, Wenxin Luo, Dan Liu, Guiyi Ji   +11 more
wiley   +1 more source

Analyzing thyroid dysfunction in the climacteric

Journal of Mid-life Health, 2018
Perimenopause and menopause is an integral part of every woman's life constituting about 30% of the Indian female population. Hypothyroidism is a condition that can mimic menopausal symptoms very often. Therefore, routine screening of thyroid function in the climacteric and menopausal period to determine subclinical thyroid disease can be recommended ...
Subrat Panda, Ananya Das
openaire   +3 more sources

Thyroid Dysfunction and Cytological Patterns among Patients Requested for Thyroid Function Test in an Endemic Goiter Area of Gondar, North West Ethiopia

International Journal of Endocrinology, 2019
Background. Thyroid dysfunction is the most common endocrine disorder in clinical practice, and about half of the population with thyroid dysfunction remains undiagnosed.
Daniel Asmelash, Kumlgn Tesfa, Belete Biadgo   +2 more
doaj   +1 more source

Thyroid function in pregnancy [PDF]

, 2018
Thyroid hormones are essential for pregnancy maintenance and correct foetal development; even a mild thyroid disturbance can cause potential adverse consequences on obstetric outcomes and foetal wellbeing.
Lazarus, John H., Muller, Ilaria, Lazarus, John, Taylor, Peter N., Taylor, Peter   +4 more
core   +1 more source

Divergent prognostic effects of pre-existing and treatment-emergent thyroid dysfunction in patients treated with immune checkpoint inhibitors

, 2022
BACKGROUND: Thyroid dysfunction is among the most common autoimmune diseases and immune checkpoint inhibitor (ICI)-induced immune-related adverse events (irAE).
Gerber, David E, Lu, Rong, Xie, Donglu, von Itzstein, Mitchell S, Wang, Yiqing, von Itzstein, Mitchell S., Gerber, David E., Ali, Sadia, Xie, Yang, Cai, Jennifer, Gonugunta, Amrit S., Sheffield, Thomas, Gonugunta, Amrit S, Fattah, Farjana J, Fattah, Farjana J.   +14 more
core   +1 more source

Essential Updates 2024–2025: Surgical Strategy for Esophageal Cancer Toward a New Paradigm in the Era of Immunotherapy and Personalization

Annals of Gastroenterological Surgery, EarlyView.
This review summarizes key advances from 2024 to 2025 that are reshaping esophageal cancer surgery toward a strategy‐oriented, personalized paradigm through the integration of immunotherapy, population aging, and intelligent technologies. Adjuvant nivolumab after neoadjuvant chemoradiotherapy remains the only perioperative approach with durable benefit,
Shuichiro Oya, Koichi Yagi, Yoshifumi Baba   +2 more
wiley   +1 more source