Results 51 to 60 of about 5,957,667 (290)
Advanced Science, EarlyView.This study reveals that large tumors secrete more chemokine CXCL3, which recruits immunosuppressive neutrophils to the periphery, thereby impairing the activation and memory of systemic tumor‑reactive CD8+ T cells. CXCL3 antagonism restores systemic immune memory and enhances the antitumor efficacy of anti‑PD‑1 therapy, offering a potential strategy to
Ji Wang +15 more
wiley +1 more source
Teprotumumab in advanced reactivated thyroid eye disease
American Journal of Ophthalmology Case Reports, 2022 Purpose: To report the case of a patient with reactivated, refractory thyroid eye disease (TED) treated with teprotumumab. Observations: A 51-year-old female with a 16-year history of thyroid eye disease previously treated with orbital decompression and ...
Olivia T. Cheng, Dianne M. Schlachter
doaj +1 more source
Thyroid Orbitopathy and Dry Eye
, 2011 Thyroid orbitopathy (TO) is an inflammatory autoimmune disease of the orbital and periorbital tissues that is characterized by the presence of autoantibodies against thyroid-stimulating hormone receptor (TSH-R).
Canan Gürdal, Özge Saraç
core +1 more source
AGING MEDICINE, EarlyView.Blood‐based biomarkers are emerging as accessible tools for Alzheimer's disease screening, diagnosis, risk stratification, and longitudinal monitoring. This review summarizes major biomarkers, including Aβ42/Aβ40, phosphorylated tau species, NfL, GFAP, genetic risk markers, and exploratory inflammatory, synaptic, and proteomic candidates.
Shuangshuang Li, Lin Huang, Qihao Guo
wiley +1 more source
Медицинская иммунология, 2017 We searched for a possible target tissue in eye orbit for thyroid autoantibodies in endocrine ophthalmopathy (Graves’ disease), using correlation analysis method. We examined a group of 139 patients (278 eye orbits) with thyroid-associated ophthalmopathy
V. G. Likhvantseva +4 more
doaj +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Arthrogryposis Multiplex Congenita (AMC) encompasses several hundred conditions with diverse genetic, pathophysiological, and clinical origins. The overarching EXPLAIN study explores underlying causes and implications of AMC and represents the largest clinical cohort of adults with AMC reported to date.
My Vuong Hermansen +5 more
wiley +1 more source
Bilateral versus unilateral thyroid eye disease
Indian Journal of Ophthalmology, 2011 Aims: The aim of this study was to compare demographics, clinical manifestations, associated systemic and ocular factors, severity and activity of patients with unilateral thyroid eye disease (U-TED) versus bilateral thyroid eye disease (B-TED ...
Mohsen Bahmani Kashkouli +6 more
doaj +1 more source
Methotrexate for the Treatment of Thyroid Eye Disease [PDF]
Journal of Ophthalmology, 2014 Background/Aim. To evaluate the efficacy of methotrexate for the treatment of thyroid eye disease (TED).Methods. 36 consecutive patients with active TED, previously treated with corticosteroids but stopped due to the occurrence of side effects, were commenced on methotrexate therapy.
STRIANESE, DIEGO +11 more
openaire +5 more sources
British Journal of Clinical Pharmacology, EarlyView.Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad +4 more
wiley +1 more source
Retrospective Review of Pediatric Thyroid Eye Disease Cases Referred to Nicklaus Children’s Hospital
The Pan-American Journal of Ophthalmology, 2018 Purpose: We evaluate presenting features and treatment options of pediatric thyroid eye disease, and discuss the morbidity of this condition in the pediatric population.
M Enghelberg +3 more
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