Results 81 to 90 of about 467,067 (355)

Understanding miR‐200c: an Important Player in Resistance to Cancer Treatment

Advanced Therapeutics, EarlyView.
How can one microRNA alter cancer's response to therapy? miR‐200c plays a central role in therapeutic resistance by modulating epithelial‐mesenchymal transition, apoptosis, cancer stemness features, and drug efflux. This review outlines the context‐dependent functions of miR‐200c in various cancers and highlights its potential as both a biomarker and a
Fatma Sanli, Omer Faruk Karatas
wiley   +1 more source

Physiological changes in thyroid function during pregnancy: an approach to the interpretation of thyroid tests = Cambios fisiológicos de la función tiroidea en el embarazo: bases para la interpretación de las pruebas tiroideas

Iatreia, 2013
A proper understanding of thyroid physiology and its changes through pregnancy is critical to suspect diseases affecting the functioning of the hypothalamic-pituitary-thyroid axis, and to make a proper interpretation of the tests that measure its ...
Córdoba Ramírez, Nathalia, García Botina, Hernán David, Builes Barrera, Carlos Alfonso   +2 more
doaj  

Iodine concentration and content measured by dual-source computed tomography are correlated to thyroid hormone levels in euthyroid patients: a cross-sectional study in China

BMC Medical Imaging, 2020
Background The aim of this study was to investigate the correlation of the dual energy CT measured iodine concentration and total iodine content with blood measured thyroid parameters.
Zheng-Teng Li, Rui Zhai, Hong-Mei Liu, Min Wang, Dong-Mei Pan   +4 more
doaj   +1 more source

Thyroid function in pregnancy [PDF]

British Medical Bulletin, 2010
Advances in understanding the physiology of thyroid function in normal pregnancy have highlighted the importance of the consequences of abnormal function on obstetric outcome and foetal well-being. Pubmed search was done using the terms thyroid and pregnancy.
openaire   +3 more sources

Identification of a novel modulator of thyroid hormone receptor-mediated action [PDF]

, 2012
Diabetes is characterized by reduced thyroid function and altered myogenesis after muscle injury. Here we identify a novel component of thyroid hormone action that is repressed in diabetic rat muscle. Methodology/Principal Findings.
Bach González, Daniel, Baumgartner, Bernhard G., Burghardt Coll, Hans, Camps Camprubí, Marta, Duran, Jordi, González, Meritxell, Oriola Ambrós, Josep, Orpinell Mercadé, Meritxell, Palacín Prieto, Manuel, Paz, José Carlos, Ribas, Vicent, Rivera Fillat, Francisca, Villar, Ana Victoria, Zorzano Olarte, Antonio   +13 more
core   +3 more sources

Glucose Deprivation‐Induced Disulfidptosis via the SLC7A11‐INF2 Axis: Pan‐Cancer Prognostic Exploration and Therapeutic Validation

Advanced Science, EarlyView.
Glucose deprivation or GLUT1 inhibition induces disulfidptosis in SLC7A11high ovarian cancer cells by promoting cystine accumulation, NADPH/ATP depletion, and F‐actin disulfide formation. SLC7A11 interacts with INF2 to further increase H₂O₂ levels and impair mitochondrial fission, suppressing cell migration. Targeting the SLC7A11–INF2 axis represents a
Zhenyu Song, Qiuming Yao, Lina Huang, Dan Cui, Jun Xie, Leilei Wu, Jianfeng Huang, Bo Zhai, Dan Liu, Xiao Xu   +9 more
wiley   +1 more source

Thyroid Function and ADHD

Pediatric Neurology Briefs, 1994
Routine thyroid function studies in a community referred sample of boys with ADHD were examined for evidence of generalized resistance to thyroid hormone at the National Institute of Mental Health, Bethesda, MD.
J Gordon Millichap
doaj   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

Advanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu, Xiaofan Liang, Yiming Qin, Yuxuan Li, Yue Liu, Congcong Liu, Zongxuan Lin, Chunxuan Geng, Yanqi Xu, Daimin Wei, Yingying Qin, Han Zhao, Yuqing Zhang, Zi‐Jiang Chen   +13 more
wiley   +1 more source

Influence of thyroid hormones on biochemical parameters of liver function: a case-control study in North Indian population [PDF]

, 2013
Normal level of thyroid hormones is important for normal hepatic function and thyroid dysfunction may modulate metabolic function of liver. The purpose of this study is to determine whether liver function is associated with subclinical and overt ...
Amita Yadav, Jayashree Bhattacharjee, Megha K Arora, Ritu Singh, Sarika Arora, Vandana Saini   +5 more
core   +2 more sources

Real‐Time Evolutionary Landscape of the Bronchial Epithelium and Corresponding Dynamic Immune Cell Alterations in Lung Squamous Cell Carcinogenesis

Advanced Science, EarlyView.
Lung squamous cell carcinoma (LUSC) is often preceded by sequential premalignant lesions with an increasing probability of malignant progression. Using single‐cell RNA sequencing, the dynamic cellular evolution from normal lung to LUSC tissues is delineated; clonal structure of premalignant and malignant epithelium is reveled; the conversion of immune ...
Baohong Luo, Yuting Luo, Sicheng Chen, Tiantian Yang, Bixia Liu, Xiting Liao, Xiaoke Zheng, Tian Tian, Jinxu Liu, Qinru Zhan, Xiaohua Situ, Zhongpeng Xie, Yanxia Wang, Zhe‐Sheng Chen, Honglei Chen, Zheng Yang, Zunfu Ke   +16 more
wiley   +1 more source