Results 171 to 180 of about 1,914,121 (297)

Thyroid hormone receptor α1: a novel regulator of thyroid cancer cell differentiation. [PDF]

Oncogene, 2023
Hwang E, Doolittle WKL, Zhu YJ, Zhu X, Zhao L, Yu Y, Cheng SY.   +6 more
europepmc   +1 more source

Hepatocyte‐Centered Regulation of MASH Fibrosis: From Animal Models to Molecular Mechanisms and Targeted Therapies

iNew Medicine, EarlyView.
This review highlights hepatocytes as active regulators of MASH fibrosis through secreted proteins, metabolites, and extracellular vesicles that modulate hepatic stellate cell activation. These hepatocyte–stellate cell communication pathways provide a mechanistic framework for developing targeted antifibrotic therapies, including hepatocyte‐directed ...
Eui Jung Jung, Xiaobo Wang
wiley   +1 more source

Specific peptide enrichment strategies for neuropsychiatric disorders: From material design to diagnostic applications

Interdisciplinary Medicine, EarlyView.
This review outlines specific peptide enrichment strategies, including metal, magnetic oxides, functional polymers, and antibody‐based approaches, and their mechanisms, highlighting applications in biomarker discovery for major neurological and psychiatric disorders.
Xue Zhang, Yejiao Shi, Minghui Guo, Yang Huang, Yirong Wang, Leping Huang, Helena S. Azevedo, Honggang Hu, Xin Dong   +8 more
wiley   +1 more source

Novel Thyroid Hormone Receptor β Gene Variant (F245L) Causing Mild Resistance to Thyroid Hormone. [PDF]

JCEM Case Rep
Yamagami K, Kanamoto N, Yamashita Y, Sasai Y, Tagami T.   +4 more
europepmc   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

The specific features of the thyroid hormone receptor gene <i>THRB</i> polymorphism in indigenous populations of Siberia. [PDF]

Vavilovskii Zhurnal Genet Selektsii
Malyarchuk BA, Pokhilyuk NV, Denisova GA, Litvinov AN.   +3 more
europepmc   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Autoimmune thyroiditis promotes breast cancer progression: exploratory role of thyroid hormone receptor beta signaling disruption. [PDF]

Breast Cancer Res
Li S, Jiang QL, Gong HZ, Zeng Y, Jiang J.   +4 more
europepmc   +1 more source

Using Labs Wisely: A collaboration between Choosing Wisely Canada and over 150 Canadian hospitals

Journal of Hospital Medicine, EarlyView.
Abstract Background Many in‐hospital laboratory tests are unnecessary. Unnecessary testing is associated with patient harm, fiscal inefficiency, and environmental waste. Objectives In 2021, Choosing Wisely Canada launched the Using Labs Wisely (ULW) hospital collaborative to (1) build national expertise on reducing unnecessary testing, (2) share ...
Thomas Bodley, Bilal Shakir, Gillian Hurwitz, Adina Weinerman, Lisha Lo, Saranya Arnoldo, Chloe Chow, Janet Simons, Wendy Levinson   +8 more
wiley   +1 more source

Thyroid hormone receptor α signaling shapes innate and adaptive immune responses during viral infection. [PDF]

Eur Thyroid J
Wenzek C, Knuschke T, Hönes GS, Boelen A, Klopfleisch R, Zwanziger D, Heuer H, Westendorf AM, Moeller LC, Führer D.   +9 more
europepmc   +1 more source