Results 11 to 20 of about 175,066 (304)

The Developmental Toxicity and Endocrine-Disrupting Effects of Fenpropathrin on Gobiocypris rarus during the Early Life Stage

open access: yesToxics, 2023
In the present study, the developmental toxicity and endocrine-disrupting effects of fenpropathrin on Gobiocypris rarus during the early life stage were studied using a semi-static water exposure method.
Lei Wang   +6 more
doaj   +1 more source

Thyroid Hormone Resistance in a Preterm Infant with a Novel THRB Mutation [PDF]

open access: yesNeonatal Medicine, 2019
Resistance to thyroid hormone (RTH) is a condition caused by a mutation in the thyroid hormone receptor gene. It is rarely reported in individuals with no family history of RTH or in premature infants, and its clinical presentation varies. In our case, a
Joon Yeol Bae   +6 more
doaj   +1 more source

Thyroid disruption by Di-n-butyl phthalate (DBP) and mono-n-butyl phthalate (MBP) in Xenopus laevis. [PDF]

open access: yesPLoS ONE, 2011
BACKGROUND: Di-n-butyl phthalate (DBP), a chemical widely used in many consumer products, is estrogenic and capable of producing seriously reproductive and developmental effects in laboratory animals.
Ouxi Shen   +13 more
doaj   +1 more source

Central hyperthyroidism combined with Graves' disease: case series and review of the literature

open access: yesEuropean Thyroid Journal, 2023
Background: Central hyperthyroidism is characterized by elevated free thyroid hormone and unsuppressed thyroid-stimulating hormone (TSH), and this laboratory feature includes TSH-secreting pituitary adenoma (TSHoma) and resistance to thyroid hormone β ...
Caiyan Mo   +4 more
doaj   +1 more source

Resistance to thyroid hormone due to a novel mutation of thyroid hormone receptor beta gene [PDF]

open access: yesAnnals of Pediatric Endocrinology & Metabolism, 2014
Resistance to thyroid hormone (RTH) is a rare inherited syndrome characterized by diminished response of the target tissue to thyroid hormone caused, in the majority of cases, by mutation of the thyroid hormone receptor beta (THRβ) gene. Despite elevated
Jae Hee Lee, Eun Young Kim
doaj   +1 more source

Reduced pituitary size in subjects with mutations in the THRB gene and thyroid hormone resistance

open access: yesEndocrine Connections, 2022
Background: Thyroid hormone action is mediated by two forms of thyroid hormone receptors (α, β) with differential tissue distribution. Thyroid hormone recepto r β (TRβ) mutations lead to resistance to thyroid hormone action in tissues predominantly ...
Marcus Heldmann   +11 more
doaj   +1 more source

Changes in Clinical Activity, Serum Autoantibody Levels, and Chorioretinal Vessels After Systemic Glucocorticoid Therapy in Thyroid Eye Disease

open access: yesOphthalmology and Therapy, 2023
Introduction The aim of this study was to investigate changes in the Clinical Activity Score, serum thyroid-stimulating hormone receptor antibody and thyroid-stimulating immunoglobulin levels, chorioretinal blood vessels, and extraocular muscle thickness
Jaekyoung Lee, Dong Cheol Lee
doaj   +1 more source

Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism

open access: yesNature Communications, 2022
Thyroid hormones regulate systemic glucose metabolism through incompletely understood mechanisms. Here the authors report that hepatic thyroid hormone receptor β mediates the effects of the thyroid hormone T3 on systemic glucose homeostasis by modulating
Ying Yan   +20 more
doaj   +1 more source

A thyroid hormone receptor-dependent glucocorticoid induction. [PDF]

open access: yes, 1994
Glucocorticoid and thyroid hormones exert their effects in many body tissues by binding to their respective receptors. The search for possible cross-talking mechanisms in overlapping target cells led to the discovery of synergism between a thyroid ...
Leers, Joerg   +3 more
core   +1 more source

Thyroid hormone receptors and ligand, tissue distribution and sexual behavior [PDF]

open access: yes, 2018
The thyroid hormones (THs) triiodothyronine (T3) and tetraiodothyronine, or thyroxine (T4), not only dramatically impact on development and differentiation, but also on the sexual and reproductive function.
Carosa, E, Jannini, Ea, Lenzi, A
core   +1 more source

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