Results 31 to 40 of about 1,772,358 (255)

Toxic effects of Decabromodiphenyl ether (BDE-209) on thyroid of broiler chicks by transcriptome profile analysis

open access: yesEcotoxicology and Environmental Safety, 2021
The wide usage of decabromodiphenyl ether (BDE-209) results in its increasing occurrence in the environment and increasing attention in regard to human and animal health. BDE-209 is an endocrine disruptor for hypothyroidism, but the toxicity mechanism is
Lin Cheng   +7 more
doaj   +1 more source

A Novel Role for Thyroid Hormone Receptor Beta in Cellular Radiosensitivity [PDF]

open access: yes, 2008
Thyroid hormone receptors (THRs) widely govern cell growth, differentiation and metabolism acting in a ligand- and cofactor-dependent manner to modulate tissue-specific gene expression. Given a large variety of genes regulated by THRs and multiplicity of
Hiroyuki NAMBA   +17 more
core   +1 more source

Triiodothyronine (T3) promotes brown fat hyperplasia via thyroid hormone receptor α mediated adipocyte progenitor cell proliferation

open access: yesNature Communications, 2022
Thyroid hormone (TH) action regulates brown adipose tissue thermogenic capacity through incompletely understood mechanisms. Here the authors report that T3, the active form of TH, increases thermogenic capacity via thyroid hormone receptor α-mediated ...
Shengnan Liu   +22 more
doaj   +1 more source

The predictive value of thyroid hormone sensitivity parameters for cervical lymph node metastasis in patients with differentiated thyroid cancer

open access: yesAnnals of Medicine
Objective To comprehensively investigate the predictive value of thyroid hormone sensitivity parameters for cervical lymph node metastasis in patients diagnosed with differentiated thyroid cancer (DTC) undergoing total thyroidectomy and neck lymph node ...
Jingcheng Bi   +6 more
doaj   +1 more source

Thyroid hormone receptor beta: Relevance in human health and diseases

open access: yesEndocrine and Metabolic Science, 2023
Thyroid Hormone Receptor (THR) is a member of the nuclear receptor (NR) superfamily, best defined as intracellular ligand-modulated transcription factors. Thyroid hormone (TH), by binding to THR, regulates several physiological and metabolic processes, e.
Ghausiya Rehman   +3 more
doaj   +1 more source

Methods to assess iron and iodine status [PDF]

open access: yes, 2008
Four methods are recommended for assessment of iodine nutrition: urinary iodine concentration, the goitre rate, and blood concentrations of thyroid stimulating hormone and thyroglobulin.
Zimmermann, Michael B., Zimmermann, M.B.
core   +1 more source

Characterization of a Low Affinity Thyroid Hormone Receptor Binding Site within the Rat GLUT4 Gene Promoter

open access: yes, 2023
Previous studies have demonstrated that thyroid hormone (T3) stimulates insulin-responsive glucose transporter (GLUT4) transcription and protein expression in rat skeletal muscle.
Dohm, G. Lynis   +4 more
core  

Thyroid hormone regulation of gene expression in primary cerebrocortical cells: role of thyroid hormone receptor subtypes and interactions with retinoic acid and glucocorticoids. [PDF]

open access: yesPLoS ONE, 2014
The effects of thyroid hormone on brain development and function are largely mediated by the binding of 3,5,3'-triiodo-L-thyronine (T3) to its nuclear receptors (TR) to regulate positively or negatively gene expression.
Pilar Gil-Ibáñez   +2 more
doaj   +1 more source

Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review [PDF]

open access: yes, 2008
The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed.
Brand, H., van den   +5 more
core   +1 more source

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider   +15 more
wiley   +1 more source

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