Results 191 to 200 of about 2,553,881 (244)

Pituitary resistance to thyroid hormone caused by a novel mutation (H435A) in the thyroid hormone receptor beta: A case report. [PDF]

open access: yesMedicine (Baltimore), 2018
Yu C   +9 more
europepmc   +1 more source

Female genital lichen sclerosus

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
This review provides a comprehensive overview of clinical presentation and emerging evidence supporting a predominantly immune‐mediated pathogenesis characterized by Th1‐skewed inflammation, epithelial dysfunction and progressive fibrosis. Contributory factors including the emerging role for occlusive exposure of susceptible epithelium to urine are ...
Ashley Spencer, Sandra Jerkovic Gulin
wiley   +1 more source

Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation. [PDF]

open access: yesProc Natl Acad Sci U S A, 2017
Gao X   +8 more
europepmc   +1 more source

Body size of male Atlantic salmon (Salmo salar L.) at introduction of a 5‐week LD12:12 winter signal influences their decision to mature early or smoltify

open access: yesJournal of Fish Biology, EarlyView.
Abstract Sexual maturation of male Atlantic salmon post‐smolts (‘jacking’) is undesired in aquaculture and seems to occur due to the intensification in modern facilities. Maturation depends on internal and external factors (temperature, photoperiod, feed availability, energy levels, body size, genetic background) that act on the brain‐pituitary‐gonad ...
Enrique Pino‐Martinez   +5 more
wiley   +1 more source

Cancer co‐medication quality in older patients with polypharmacy: A large randomized trial testing a medication review versus usual care

open access: yesJournal of Internal Medicine, EarlyView.
Abstract Background Evidence from randomized controlled trials (RCTs) testing medication reviews in geriatric oncology is sparse. Methods We conducted a single‐blinded RCT in ten rehabilitation clinics across Germany. Patients with common cancers, aged ≥ 65 years, and polypharmacy (regularly ≥ five drugs) were randomly allocated in equal proportions to
Miriam Degen   +15 more
wiley   +1 more source

Metabolic Adaptations to Weight Loss in Obese Senior Dogs: Effects on Energy Expenditure, Protein Turnover, and Voluntary Physical Activity

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Implications of obesity and weight loss (WL) for energy and protein metabolism are not fully understood, particularly in senior dogs. This study evaluated changes in body composition, energy expenditure (EE), protein turnover (PT), and voluntary physical activity (VPA) in senior dogs in maintenance and after 10% and 20% WL.
Ticiane Giselle Bitencourt Freire   +9 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger   +5 more
wiley   +1 more source

Periodontal Salutogenesis: Why Are Some People Resistant to Oral Microbial Dysbiosis and Destructive Inflammation?

open access: yesJournal of Periodontal Research, EarlyView.
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos   +4 more
wiley   +1 more source

Functional analysis of thyroid hormone receptor beta in Xenopus tropicalis founders using CRISPR-Cas. [PDF]

open access: yesBiol Open, 2018
Sakane Y   +7 more
europepmc   +1 more source

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