Results 11 to 20 of about 119,841 (316)
Thyroid Hormone Transporters [PDF]
Biochemical Society Transactions, 2005 Thyroid hormone is essential for the development of the brain and the nervous system. Cellular entry is required for conversion of thyroid hormones by the intracellular deiodinases and for binding of T(3) to its nuclear receptors. Several transporters capable of thyroid hormone transport have been identified. Functional expression studies using Xenopus
Friesema, Edith +3 more
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Thyroid Hormone Transporters [PDF]
Endocrine Reviews, 2019 AbstractThyroid hormone transporters at the plasma membrane govern intracellular bioavailability of thyroid hormone. Monocarboxylate transporter (MCT) 8 and MCT10, organic anion transporting polypeptide (OATP) 1C1, and SLC17A4 are currently known as transporters displaying the highest specificity toward thyroid hormones.
Stefan Groeneweg +4 more
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Therapy with L-thyroxine and Omnadren after Cardiac Surgery. A Case Report [PDF]
Folia Medica, 2019 Background: Cardiopulmonary bypass in cardiac surgery produces systemic inflammatory response and catabolic state. Severe stress frequently causes abnormalities in thyroid hormones in the absence of primary thyroid disease, defined as sick euthyroid ...
Georgi J. Stoitsev +6 more
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Frontiers in Molecular Neuroscience, 2022 Thyroid hormones clearly play a role in the seasonal regulation of reproduction, but any role they might play in song behavior and the associated seasonal neuroplasticity in songbirds remains to be elucidated.
Jasmien E. M. J. Orije +12 more
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Thyroid dysfunction and kidney diseases
Počki, 2019 Thyroid hormones provide normal functioning of the kidneys, which in turn are not only an organ for the metabolism and excretion of thyroid hormones but also serve as targets for the action of certain thyroid hormones.
О.О. Melnik
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Thyroid Hormones and Cancer: A Comprehensive Review of Preclinical and Clinical Studies
Frontiers in Endocrinology, 2019 Thyroid hormones take major part in normal growth, development and metabolism. Over a century of research has supported a relationship between thyroid hormones and the pathophysiology of various cancer types.
Eilon Krashin +7 more
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Intranasal delivery of Thyroid hormones in MCT8 deficiency.
PLoS ONE, 2020 Loss of function mutations in the gene encoding the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) lead to severe neurodevelopmental defects in humans associated with a specific thyroid hormone phenotype manifesting high serum 3,5,3 ...
Carmen Grijota-Martínez +5 more
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Role of maternal thyroid hormones in the developing neocortex and during human evolution
Frontiers in Neuroanatomy, 2013 The importance of thyroid hormones during brain development has been appreciated for many decades. In humans, low levels of circulating maternal thyroid hormones, e.g.
Denise eStenzel, Wieland B eHuttner
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Folia Endocrinologica Japonica, 1993 Most thyroxine (T4) secreted from the thyroid is deiodinated in peripheral tissues. At least three isozymes are known in iodothyronine deiodinase which catalyzes the conversion of T4 to triiodothyronine (T3) or reverse T3. Type I 5'-deiodinase (5'D-I) exists in most tissues including the liver, kidney and thyroid.
M, Inada, M, Nishikawa
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Thyroid hormone sensitivity and diabetes onset: a longitudinal cross-lagged cohort
Frontiers in Endocrinology, 2023 PurposeThyroid hormones sensitivity is a newly proposed clinical entity closely related with metabolic health. Prior studies have reported the cross-sectional relationship between thyroid hormones sensitivity and diabetes; however, the longitudinal ...
Cancan Cui +8 more
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