Results 51 to 60 of about 179,790 (311)

Remodeling Of The Bone Tissue Of Rats Of Different Lines After Melatonin Effect [PDF]

, 2016
The markers of remodeling of bone tissue (BT) were studied after the impact of pharmacologic dose of melatonin (5 mg/kg of the animal body weight) during 28 days for 3-months rats-males of Wistar and SHR lines.
Berezovskyi, V. (Vadim), Litovka, I. (Irina), Zhernoklov, U. (Uliana)   +2 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Thyroid dysfunction in the ageing patient

Mìžnarodnij Endokrinologìčnij Žurnal
Thyroid dysfunction is a common endocrine disorder in the general population, with a reported prevalence of 10–15 %. This rate is higher in older adults, with an estimated prevalence of 25 % in some populations.
O.V. Bilookyi, V.L. Vasiuk, O.A. Shupik
doaj   +1 more source

Thyroid Gene Mutations in Pregnant and Breastfeeding Women Diagnosed With Transient Congenital Hypothyroidism: Implications for the Offspring’s Health

Frontiers in Endocrinology, 2021
Fetus and infants require appropriate thyroid hormone levels and iodine during pregnancy and lactation. Nature endorses the mother to supply thyroid hormones to the fetus and iodine to the lactating infant.
Maria C. Opazo, Maria C. Opazo, Juan Carlos Rivera, Pablo A. Gonzalez, Susan M. Bueno, Alexis M. Kalergis, Alexis M. Kalergis, Claudia A. Riedel   +7 more
doaj   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Associations of blood metal exposure with thyroid hormones in Chinese pregnant women: A cross-sectional study

Environment International, 2018
Background: Few epidemiological studies have investigated associations of exposure to multiple metals with thyroid hormone homeostasis, especially for the pregnant women.
Jing Guo, Na Lv, Jun Tang, Xue Zhang, Lihe Peng, Xiaofu Du, Shuai Li, Qiong Luo, Dan Zhang, Guangdi Chen   +9 more
doaj   +1 more source

Thyroid hormone, thyroid hormone receptors, and cancer: a clinical perspective [PDF]

Endocrine-Related Cancer, 2013
Thyroid hormones (THs) may play a role in diseases other than hyper- and hypothyroidism. Several lines of evidence suggest tumor-promoting effects of TH and TH receptors. They are possibly mediated by phosphatidylinositol-3-kinase and MAPK and involve among others stimulation of angiogenesis via αvβ3.
Möller, Lars, Führer, Dagmar
openaire   +3 more sources

Neurobehavioral function and low-level exposure to brominated flame retardants in adolescents : a cross-sectional study [PDF]

, 2012
Background: Animal and in vitro studies demonstrated a neurotoxic potential of brominated flame retardants, a group of chemicals used in many household and commercial products to prevent fire.
Baeyens, Willy, Bruckers, Liesbeth, Covaci, Adrian, Croes, Kim, Den Hond, Elly, Dirtu, Alin C, Kiciński, Michał, Nawrot, Tim S, Nelen, Vera, Schoeters, Greet, Sioen, Isabelle, Van Larebeke, Nicolas, Viaene, Mineke K   +12 more
core   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Ramadan fasting and thyroid function [PDF]

Journal of Fasting and Health, 2017
Fasting is one of Islamic Five Pillars and it is an Islamic obligations. Even though fasting during Ramadan month is an obligatory, if this obligatory has dangerous effects on the human health, it is forbidden.
Sayed Alireza Mirsane, Shima Shafagh, Nasrin Oraei   +2 more
doaj   +1 more source