Results 61 to 70 of about 119,841 (316)

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

KADAR ANTIBODI-TIROPEROKSIDASE DAN ANTIBODI-TIROGLOBULIN PADA WANITA USIA SUBUR DI DAERAH ENDEMlS GAKI

open access: yesMedia Gizi Mikro Indonesia, 2012
Background: Thyroid hormones play a critical role in human. Disorders of the thyroid gland result primary from autoimmune processes that either stimulate the over production of thyroid hormones (hyperthyroid) or causes glandular destruction and hormones ...
Agus Wibowo   +2 more
doaj   +1 more source

TMEM131‐Mediated Soluble TRAIL Triggered Type II Alveolar Epithelial Cell Senescence in Radiation‐Induced Lung Injury

open access: yesAdvanced Science, EarlyView.
TMEM131 recruits the COPII complex to accelerate TRAIL transportation from endoplasmic reticulum to Golgi apparatus, and promotes soluble TRAIL secretion. TRAIL inhibits mitophagy and induces senescence through DR5 receptor in type II alveolar epithelial cells, ultimately driving radiation‐induced lung injury (RILI) progression.
Linzhi Han   +10 more
wiley   +1 more source

Effect of Aqueous Extract of Foeniculum Vulgare on Thyroid Hormones and the Expression of its Receptors in the Ovaries of BALB/C Mice [PDF]

open access: yesJournal of Advanced Biomedical Sciences, 2020
Background & Objective: Fennel (Foeniculum vulgare) is one of the ancient plants that has various medicinal effects. The main hormones produced by the thyroid gland are thyroxine (T4) and triiodothyronine (T3), which regulate the body's growth and ...
Fatemeh Javadi   +5 more
doaj  

Herpes zoster ophthalmicus with ocular involvement in overtreated hyperthyroidism

open access: yesIndian Journal of Ophthalmology, 2020
A 25-year-old man, with a history of hyperthyroidism presented with herpes zoster ophthalmicus (HZO) with neurotrophic ulcer and superadded infection 4 weeks after a sudden decrease in his thyroid hormones, caused by overtreatment of hyperthyroidism and ...
Surbhi Khurana   +3 more
doaj   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

open access: yesAdvanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu   +8 more
wiley   +1 more source

Overlapping action of T3 and T4 during Xenopus laevis development

open access: yesFrontiers in Endocrinology
Thyroid hormones are involved in many biological processes such as neurogenesis, metabolism, and development. However, compounds called endocrine disruptors can alter thyroid hormone signaling and induce unwanted effects on human and ecosystems health ...
Alicia Tribondeau   +5 more
doaj   +1 more source

The impact of thyroid hormone dysfunction on ischemic heart disease

open access: yesEndocrine Connections, 2019
Thyroid hormones have a central role in cardiovascular homeostasis. In myocardium, these hormones stimulate both diastolic myocardial relaxation and systolic myocardial contraction, have a pro-angiogenic effect and an important role in extracellular ...
Madalena von Hafe   +4 more
doaj   +1 more source

Demonstration of reciprocal diurnal variation in human serum T3 and rT3 concentration demonstrated by mass spectrometric analysis and establishment of thyroid hormone reference intervals

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2020
Background: There has been a wide range of reference intervals proposed in previous literature for thyroid hormones due to large between-assay variability of immunoassays, as well as lack of correction for collection time.
Qian Sun   +9 more
doaj   +1 more source

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