Results 61 to 70 of about 1,450,120 (315)

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

Advanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou, Jia Cong, Rongguang Peng, Dichen Yang, Chenchen Dong, Jing Xie, Jiqi Yan, Jie Kuang, Fubin Li, Leng Siew Yeap, Xiaoyan Xie, Haolong Yin, Rulai Han, Liyun Shen, Yulin Zhou, Guang Ning, Shu Wang, Weiqing Wang, Lei Ye   +18 more
wiley   +1 more source

Effect of Aqueous Extract of Foeniculum Vulgare on Thyroid Hormones and the Expression of its Receptors in the Ovaries of BALB/C Mice [PDF]

Journal of Advanced Biomedical Sciences, 2020
Background & Objective: Fennel (Foeniculum vulgare) is one of the ancient plants that has various medicinal effects. The main hormones produced by the thyroid gland are thyroxine (T4) and triiodothyronine (T3), which regulate the body's growth and ...
Fatemeh Javadi, Monireh Movahedi, mahmood Barati, Seyedeh Masoomeh Amiri, Lida Kooshesh, Fereshteh Golab   +5 more
doaj  

Herpes zoster ophthalmicus with ocular involvement in overtreated hyperthyroidism

Indian Journal of Ophthalmology, 2020
A 25-year-old man, with a history of hyperthyroidism presented with herpes zoster ophthalmicus (HZO) with neurotrophic ulcer and superadded infection 4 weeks after a sudden decrease in his thyroid hormones, caused by overtreatment of hyperthyroidism and ...
Surbhi Khurana, Parul Chawla Gupta, Ashok Kumar Singh, Jagat Ram   +3 more
doaj   +1 more source

Transport of thyroid hormones via the choroid plexus into the brain: the roles of transthyretin and thyroid hormone transmembrane transporters

Frontiers in Neuroscience, 2015
Thyroid hormones are key players in regulating brain development. Thus, transfer of appropriate quantities of thyroid hormones from the blood into the brain at specific stages of development is critical.
S. Richardson, Roshen C. Wijayagunaratne, Damian G. D’Souza, V. Darras, Stijn L. J. Van Herck   +4 more
semanticscholar   +1 more source

Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2‐Mediated Mitochondrial Fusion and UCP1‐Mediated Lipid Browning in ccRCC

Advanced Science, EarlyView.
Thyroid hormone receptor β1 (TRβ) downregulation correlates with poor prognosis in clear cell renal cell carcinoma (ccRCC). Restoration of TRβ and the peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha suppresses tumor progression in ccRCC through Uncoupling protein 1 mediated tumor cell “slimming” and optic atrophy 1/mitofusin 2 ...
Xiangui Meng, Tiexi Yu, Fang Lv, Weiquan Li, Hongmei Yang, Xiaoping Zhang, Wen Xiao   +6 more
wiley   +1 more source

European multicentre study on outcome of surgery for sporadic primary hyperparathyroidism

BJS (British Journal of Surgery), EarlyView., 2020
Some 5861 patients undergoing first‐time surgery for sporadic primary hyperparathyroidism were registered in the Eurocrine® database between 2015 and 2018. The use of intraoperative parathyroid hormone measurement decreased the risk of conversion and persistent hypercalcaemia.
A. Bergenfelz, S. van Slycke, Ö. Makay, L. Brunaud   +3 more
wiley   +1 more source

KADAR ANTIBODI-TIROPEROKSIDASE DAN ANTIBODI-TIROGLOBULIN PADA WANITA USIA SUBUR DI DAERAH ENDEMlS GAKI

Media Gizi Mikro Indonesia, 2012
Background: Thyroid hormones play a critical role in human. Disorders of the thyroid gland result primary from autoimmune processes that either stimulate the over production of thyroid hormones (hyperthyroid) or causes glandular destruction and hormones ...
Agus Wibowo, Suryati Kumorowulan, Aniek Prihatin   +2 more
doaj   +1 more source

Demonstration of reciprocal diurnal variation in human serum T3 and rT3 concentration demonstrated by mass spectrometric analysis and establishment of thyroid hormone reference intervals

Therapeutic Advances in Endocrinology and Metabolism, 2020
Background: There has been a wide range of reference intervals proposed in previous literature for thyroid hormones due to large between-assay variability of immunoassays, as well as lack of correction for collection time.
Qian Sun, Lívia Avallone, Brian Stolze, Katherine A. Araque, Yesim Özarda, Jacqueline Jonklaas, Toral Parikh, Kerry Welsh, Likhona Masika, Steven J. Soldin   +9 more
doaj   +1 more source

Association of impaired sensitivity to thyroid hormones with hyperuricemia through obesity in the euthyroid population

Journal of Translational Medicine, 2023
Background Impaired sensitivity to thyroid hormones is a newly proposed clinical entity associated with hyperuricemia in the subclinical hypothyroid population. However, it is unknown whether the association exists in the euthyroid population. This study
Zhiyuan Wu, Yue Jiang, Pingan Li, Yutao Wang, Haiping Zhang, Zhiwei Li, Xia Li, Lixin Tao, Bo Gao, Xiuhua Guo   +9 more
doaj   +1 more source

Thyroid Hormones and Moderate Exposure to Perchlorate during Pregnancy in Women in Southern California

Environmental Health Perspectives, 2015
Background: Findings from national surveys suggest that everyone in the United States is exposed to perchlorate. At high doses, perchlorate, thiocyanate, and nitrate inhibit iodide uptake into the thyroid and decrease thyroid hormone production.
C. Steinmaus, M. Pearl, M. Kharrazi, B. Blount, Mark D. Miller, E. Pearce, L. Valentín-Blasini, G. Delorenze, A. Hoofnagle, Jane Liaw   +9 more
semanticscholar   +1 more source