Results 61 to 70 of about 208,684 (196)

Imaging in thyroid-associated orbitopathy [PDF]

open access: yesEuropean Journal of Endocrinology, 2001
Thyroid-associated orbitopathy (TAO) is an autoimmune condition of the orbit which is closely associated with Graves' hyperthyroidism, although either condition may exist without the other. It may antedate, coincide with or follow hyperthyroidism (1±10).
openaire   +2 more sources

Drastic Response to Olaparib in a Patient With Metastatic Castration‐Resistant Prostate Cancer Harboring BRCA2 Alterations and Near‐Threshold Tumor Mutational Burden

open access: yesIJU Case Reports, Volume 9, Issue 2, March 2026.
ABSTRACT Introduction BRCA2 alterations and high tumor mutational burden (TMB‐H) are responsible for prostate cancer; however, their co‐occurrence is uncommon, and evidence for PARP inhibition in the castration‐sensitive setting remains limited. We describe a case of metastatic castration‐resistant prostate cancer (CRPC) harboring both biomarkers ...
Kotaro Yokota   +6 more
wiley   +1 more source

A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies [PDF]

open access: yesJournal of Clinical and Diagnostic Research
Thyroid-Associated Orbitopathy (TAO), also known as Graves’ ophthalmopathy or Thyroid Eye Disease (TED), is an autoimmune condition often linked to hyperthyroidism, particularly Graves’ disease.
Iqra Mushtaq   +3 more
doaj   +1 more source

Retinal Capillary Density Reduction Contributes to Dysthyroid Optic Neuropathy via an L‐Arginine‐NO Pathway: A Metabonomics and Clinical Trial Study

open access: yesMedComm, Volume 7, Issue 3, March 2026.
Oxidative stress induces endothelial nitric oxide synthase (eNOS) uncoupling and L‐arginine depletion, reducing nitric oxide (NO) bioavailability in vascular endothelium and contributing to decreased retinal capillary density (RCD) in dysthyroid optic neuropathy (DON).
Yunhai Tu   +12 more
wiley   +1 more source

CTLA-4 and HLA genes for susceptibility to thyroid associated orbitopathy

open access: yes, 1999
Comment on Cytotoxic T lymphocyte antigen-4 (CTLA-4) gene polymorphism confers susceptibility to thyroid associated orbitopathy.
SIGNORE, Alberto   +3 more
core   +1 more source

The Diagnostic Value of Mean Apparent Propagator‐MRI in Dysthyroid Optic Neuropathy: A Quantitative Analysis of the Entire Visual Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
The diagnostic model combining orbital and intracranial MAP‐MRI parameters could significantly optimize diagnostic efficiency of dysthyroid optic neuropathy. Comprehensive MAP‐MRI parameters analysis of the entire visual pathway enables a deeper understanding of disease involvement, provides novel insights into the early accurate diagnosis and ...
Mengsha Zou   +7 more
wiley   +1 more source

Radiological signs on orbital imaging of immunoglobulin G4-related disease

open access: yesArchives of Medicine and Health Sciences, 2020
Immunoglobulin G4 (IgG4)-related disease has strong organ predilections, and orbital involvement is not rare. Eyelid puffiness with erythema, extraocular movement deficit with proptosis are common presentations, which could sometimes mimic thyroid ...
Sunny Chi Lik Au, Edwin Chan
doaj   +1 more source

Chronic Rhinosinusitis and Autoimmune Diseases: A Comprehensive Large Population‐Based Analysis

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 1, February 2026.
ABSTRACT Objectives To evaluate associations between a wide variety of autoimmune diseases and chronic rhinosinusitis without nasal polyposis (CRSsNP), CRS with nasal polyposis (CRSwNP), and the need for endoscopic sinus surgery. Methods This is a multicenter retrospective study from January 1, 2010 to July 31, 2025 utilizing data from 106 healthcare ...
Robert E. Africa   +3 more
wiley   +1 more source

Ophtalmologie orbitopathie dysthyroïdienne: du diagnostic au traitement [Thyroid associated orbitopathy: from diagnosis to treatment]

open access: yes, 2013
Mild to moderate forms of orbitopathy are common in auto-immune thyroid diseases, whereas severe forms are rare. Euthyroidism restoration, no smoking, and ocular local lubricants are necessary for all the patients.
Hamédani, M., Obéric, A.
core   +1 more source

Muscle tendon elongation with bovine pericardium (Tutopatch®) in patients with Graves’ orbitopathy; a prospective, observational, multicentre study

open access: yesActa Ophthalmologica, Volume 104, Issue 1, Page e18-e27, February 2026.
Abstract Purpose Patients with severe ocular motility restriction and/or large angle strabismus due to Graves' orbitopathy (GO) cannot be adequately addressed with conventional strabismus surgery using large muscle recessions. Muscle tendon elongation surgery, using a spacer of bovine pericardium (Tutopatch®) has emerged as a valuable alternative.
H. M. Jellema   +7 more
wiley   +1 more source

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