Results 71 to 80 of about 208,684 (196)
Journal of Paediatrics and Child Health, Volume 62, Issue 9, Page 1770-1774, September 2026.
Wenhao Duan +4 more
wiley +1 more source
Exploring tear fluid biomarkers and the ocular surface in thyroid eye disease
Abstract Purpose To examine ocular surface changes and inflammatory tear fluid biomarkers in patients with thyroid eye disease (TED). Methods We included 106 Graves' disease (GD) patients (36 without TED, 32 with active and 38 with inactive TED) and 106 age‐ and sex‐matched healthy subjects for ophthalmological evaluation, including ocular surface ...
Mikael Thomassen Neset +13 more
wiley +1 more source
Thyroid-associated orbitopathy characteristics and surgery requirement rate
Objective. To know the demographic and clinical characteristics of Thyroid Associated Orbitopathy (TAO), as well as the requirement rate of orbital surgery in patients of the Orbit Service in the National Medical Center of the West, IMSS.
Gabriela Estefania Ibarra-Elizalde (12658724) +1 more
core +1 more source
Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou +18 more
wiley +1 more source
Key Clinical Message A few cases of thyroid eye disease following alemtuzumab therapy have been described in patients with multiple sclerosis. Our patient is the first case of Graves’ orbitopathy after alemtuzumab conditioning for hematopoietic stem cell
Luminita Nicoleta Cima +5 more
doaj +1 more source
ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas +8 more
wiley +1 more source
Should I Have Teprotumumab or Surgery?
Pathophysiology of thyroid eye disease/thyroid orbitopathy and teprotumumab: In orbitopathy, it is believed that there is a cross reaction of thyroid auto-antibodies with the thyrotropin receptor (TSHR) and the insulin growth factor receptor (IGFR) on ...
Alison V. Crum
core +2 more sources
Thyroid orbitopathy (TO) is the most common cause of orbital tissue inflammation, accounting for about 60% of all orbital inflammations. The inflammatory activity and severity of TO should be diagnosed based on personal experience and according to standard diagnostic criteria.
Mariusz, Nowak +6 more
openaire +2 more sources
Purpose Thyroid eye disease (TED) is the most common orbital disorder in adults. Its initial clinical manifestations are heterogeneous and may influence early diagnosis and management. However, limited data exist on real‐world perspectives from oculoplastic surgeons who frequently manage patients with TED.
Shiqi Hui +4 more
wiley +1 more source
Thyroid Eye Disease: Current Perspectives in Pathogenesis, Risk Factors, and Management
Thyroid eye disease (TED), also referred to as Graves’ orbitopathy or thyroid-associated ophthalmopathy, is an autoimmune inflammatory disorder of the orbit that most often accompanies hyperthyroidism due to Graves’ disease.
Pratheeba Devi Nivean +3 more
doaj +1 more source

