Results 11 to 20 of about 2,969 (182)

Thyroid: Iodine Beyond the Thyronines [PDF]

open access: yesCurrent Chemical Biology, 2011
Although thyroid gland function is mainly under the control of pituitary TSH, other factors may also play a role in this process. Iodine is not used only by the thyroid to synthesize thyroid hormones but also directly influences a number of parameters ...
G. Juvenal   +6 more
semanticscholar   +5 more sources

5'-deiodinase activity and circulating thyronines in lactating cows. [PDF]

open access: yesJournal of Dairy Science, 2003
To investigate the correlation between lactation and thyroid hormone metabolism, the authors studied concentrations of total and free thyroxine (T4 and fT4), triiodothyronine (T3 and fT3), and reverse triiodothyronine (rT3) in plasma and milk, as well as
C. Pezzi   +4 more
semanticscholar   +5 more sources

Placental transfer of thyronines and thyrotropin in sheep [PDF]

open access: yesPediatric Research, 1971
Data in a number of species suggest that placental transport of thyronine is limited in extent. Data regarding placental passage of TSH is indirect but suggests little or no transfer. The present studies were conducted to quantify T4, T3 and TSH transfer directly in bothe the maternal-fetal and fetal-maternal directions.
Jean H Dussault   +2 more
core   +2 more sources

Uptake and metabolic effects of 3-iodothyronamine in hepatocytes.

open access: yesJournal of Endocrinology, 2014
3-Iodothyronamine (T1AM) is an endogenous relative of thyroid hormone with profound metabolic effects. In different experimental models, T1AM increased blood glucose, and it is not clear whether this effect is entirely accounted by changes in insulin and/
S. Ghelardoni   +4 more
semanticscholar   +2 more sources

The Chemical Determination of Liothyronine and Thyroxine in Enzymic Hydrolysates of Pork Thyroid

open access: yes, 1962
Maximum amounts of liothyronine and thyroxine were released from pork thyroid by the proteolytic action of erepsin and trypsin after incubation for 96 hr. at 39°.
W F Devlin, N R Stephenson
core   +1 more source

High‐Content Screening Comparison of 1R6F Cigarette Smoke Extract and Selected Heated Tobacco and Electronic Vapour Product Aerosol Extracts in Endothelial and Bronchial Epithelial Cell Models

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Cigarettes induce oxidative stress and DNA damage, processes that contribute to cardiovascular and pulmonary disease. High content screening (HCS) is an increasingly valuable tool for comparative toxicology because it enables simultaneous quantification of multiple mechanistic endpoints at single‐cell resolution. In this study, HCS was used to
Edgar Trelles Sticken   +9 more
wiley   +1 more source

Mogroside V Promotes Brown Adipose Thermogenesis via FTO‐m6A‐LETMD1‐UCP1 Pathway to Combat Obesity

open access: yesPhytotherapy Research, EarlyView.
Mogroside V (MV) alleviates high‐fat diet‐induced obesity and metabolic dysfunction. Mechanistically, MV suppresses FTO expression, thereby increasing m6A modification of Letmd1 mRNA and enhancing its YTHDC2‐dependent stabilization. Theincreased LETMD1 expression is associated with elevated PGC1α and UCP1 levels, contributing to brown adipocyte ...
Yuan‐hai Sun   +5 more
wiley   +1 more source

Voltage‐gated potassium channels mediate thyroid hormone control of skeletal muscle excitability

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Thyroid hormone (TH)‐dependent remodelling of potassium (K+) channel networks regulates skeletal muscle (SkM) excitability. Triiodothyronine (T3), locally generated from thyroxine (T4) by type 2 deiodinase (D2), binds thyroid hormone receptors (TRα/β) and modulates transcription via thyroid response elements (TREs).
Annarita Nappi   +12 more
wiley   +1 more source

Elucidating the cellular determinants of the end‐systolic pressure‐volume relationship of the heart via computational modelling

open access: yesThe Journal of Physiology, Volume 604, Issue 19, Page 8006-8027, 1 October 2026.
Abstract figure legend Using a multiscale computational model of left ventricular electromechanics, we investigated how sarcomere dynamics influence the end‐systolic pressure‐volume (ESPV) relationship in ejecting beats compared to isovolumetric beats.
Francesco Regazzoni   +2 more
wiley   +1 more source

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