Results 1 to 10 of about 320 (154)

Role of the thyrotropin-releasing hormone of the limbic system in mood and eating regulation

open access: yesJournal of Integrative Neuroscience, 2022
Thyrotropin-releasing hormone (TRH) and its receptors are expressed in the hypothalamus and limbic regions. Brain thyrotropin-releasing hormone actions are exerted directly through its receptors and indirectly by modulating the effects of ...
Elena Alvarez-Salas   +3 more
doaj   +1 more source

Receptor modulators associated with the hypothalamus -pituitary-thyroid axis

open access: yesFrontiers in Pharmacology, 2023
The hypothalamus-pituitary-thyroid (HPT) axis maintains normal metabolic balance and homeostasis in the human body through positive and negative feedback regulation.
Xianbin Cheng   +7 more
doaj   +1 more source

Effects of arsenic exposure on E2 and TRH and their receptor mRNA expressions in rats

open access: yes环境与职业医学, 2023
BackgroundArsenic can enter the hypothalamus to induce estrogen effect and interfere with the function of the neuroendocrine system. The thyroid endocrine system (hypothalamic-pituitary-thyroid axis) is one of the main endocrine systems, and the ...
Yuanyan LAI   +4 more
doaj   +1 more source

The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?

open access: yesFrontiers in Pharmacology, 2020
Thyrotropin releasing hormone (TRH: Glp-His-Pro-NH2) is a peptide mainly produced by brain neurons. In mammals, hypophysiotropic TRH neurons of the paraventricular nucleus of the hypothalamus integrate metabolic information and drive the secretion of ...
Jean-Louis Charli   +6 more
doaj   +1 more source

Imaging of Endoplasmic Reticulum Ca2+ in the Intact Pituitary Gland of Transgenic Mice Expressing a Low Affinity Ca2+ Indicator

open access: yesFrontiers in Endocrinology, 2021
The adenohypophysis contains five secretory cell types (somatotrophs, lactotrophs, thyrotrophs, corticotrophs, and gonadotrophs), each secreting a different hormone, and controlled by different hypothalamic releasing hormones (HRHs).
Jonathan Rojo-Ruiz   +4 more
doaj   +1 more source

Sexually dimorphic dynamics of thyroid axis activity during fasting in rats

open access: yesFrontiers in Bioscience-Landmark, 2020
Starvation induces tertiary hypothyroidism in adult rodents. Response of the hypothalamus-pituitary-thyroid (HPT) axis to starvation is stronger in adult males than in females.
Patricia Joseph-Bravo   +6 more
doaj   +1 more source

GATA2 mediates thyrotropin-releasing hormone-induced transcriptional activation of the thyrotropin β gene. [PDF]

open access: yesPLoS ONE, 2011
Thyrotropin-releasing hormone (TRH) activates not only the secretion of thyrotropin (TSH) but also the transcription of TSHβ and α-glycoprotein (αGSU) subunit genes.
Kenji Ohba   +9 more
doaj   +1 more source

Secondary amenorrhea in a woman with spinocerebellar degeneration treated with thyrotropin-releasing hormone: a case report and in vitro analysis

open access: yesJournal of Medical Case Reports, 2011
Introduction While thyrotropin-releasing hormone is known to be a prolactin-release stimulating factor, thyrotropin-releasing hormone-tartrate and its derivative, taltirelin hydrate, are used for the treatment of spinocerebellar degeneration, a ...
Kanasaki Haruhiko   +4 more
doaj   +1 more source

Thyrotropin-Releasing Hormone for Cerebellar Ataxia

open access: yesPediatric Neurology Briefs, 1989
A nine year old girl with cerebel lar ataxia that responded to thyrotropin-releasing hormone is reported from the Department of Pediatrics, Kyoto Prefectero University of Medicine, Kyoto, Japan.
J Gordon Millichap
doaj   +1 more source

Pancreatic Thyrotropin Releasing Hormone and Mechanism of Insulin Secretion

open access: yesCellular Physiology and Biochemistry, 2018
Thyrotropin releasing hormone (TRH; pGlu-His-ProNH2) is expressed also in pancreatic β cells where it is colocalized in secretory granules with insulin.
Vladimír  Štrbák
doaj   +1 more source

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