Results 31 to 40 of about 484,531 (179)
Ligand-induced selective signalling at the gonadotrophin releasing hormone receptor [PDF]
, 2008 Includes abstract.Includes bibliographical references (p. 179-202).The pituitary gonadotrophin releasing hormone (GnRH) receptor regulates reproduction by activation of Gq/11 proteins.
Coetsee, Marla Catherine
core +1 more source
Aspects of Molecular MedicineType 2 diabetes (T2D) is a chronic and prevalent multisystemic disease that significantly increases morbidity and mortality. Dysfunction of the thyroid hormone system is common in patients with T2D, increasing their risk of both hyperthyroidism and ...
Rongling Wu, Claudia Gragnoli
doaj +1 more source
PVN pathways controlling energy homeostasis
Indian Journal of Endocrinology and Metabolism, 2012 Research into the control of energy balance has tended to focus on discrete brain regions, such as the brainstem, medulla, arcuate nucleus of the hypothalamus, and neocortex.
Jennifer W Hill
doaj +1 more source
Neonatal screening and a new cause of congenital central hypothyroidism [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2014 Congenital central hypothyroidism (C-CH) is a rare disease in which thyroid hormone deficiency is caused by insufficient thyrotropin (TSH) stimulation of a normally-located thyroid gland.
Toshihiro Tajima +3 more
doaj +1 more source
Genetic and population analyses implicate thyroid‐related regulation of RNF144B in chondrocalcinosis
Arthritis &Rheumatology, Accepted Article.Objectives Chondrocalcinosis, characterized by calcium crystal deposition within articular cartilage, affects 5–15% of the general population and has recently been identified as an osteoarthritis risk factor. However, Its biological pathways remain unclear.
Yahong Wu +15 more
wiley +1 more source
Epilepsia, EarlyView.Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia +19 more
wiley +1 more source
The role of Gai in the Gonadotropin-releasing hormone (GnRH) receptor inhibition of cell proliferation [PDF]
, 2011 Includes abstract.Includes bibliographical references (leaves 72-78).The activation of Gonadotropin-releasing hormone receptor (GnRHR) by the GnRH ligand has been shown to mediate antiproliferative effects in extra-pituitary cells and in reproductive ...
Phillips, Pumza Samantha
core +1 more source
Equine Veterinary Journal, EarlyView.Abstract Background Insulin dysregulation (ID) and pituitary pars intermedia dysfunction (PPID) are common equine endocrinopathies detected by measurement of circulating insulin and adrenocorticotrophic hormone (ACTH) concentrations. Different assays may yield variable results, limiting comparability.
Nicola J. Menzies‐Gow +2 more
wiley +1 more source
Central autonomic pharmacology of thyrotropin releasing hormone [PDF]
, 1987 Thyrotropin releasing hormone (TRH, I-pyroglutamyl-l-histidyl-l-prolinamide) was the fIrst hypothalamic releasing SUbstance to be isolated, chemically characterized and synthetized /1/.
Feuerstein, Giera, Sirén, Anna-Leena
core +2 more sources
Characterization of a novel thyrotropin-releasing hormone receptor, TRHR3, in chickens
Poultry Science, 2020 The physiological roles of thyrotropin-releasing hormone (TRH) are proposed to be mediated by TRH receptors (TRHR), which have been divided into 3 subtypes, namely, TRHR1, TRHR2, and TRHR3, in vertebrates.
Xiaoxiao Li +5 more
doaj +1 more source