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Serlogical, virulence, and molecular characterization of clinical and seafood Vibrio parahaemolyticus isolates [PDF]

open access: yesMicrobiology Spectrum
In this study, 42 clinical and 114 seafood isolates of V. parahaemolyticus from Shanghai, China, were investigated. Serotypes, Kanagawa phenomenon (KP), potential virulence factors, and phylogenetic relationship (gyrB gene) of these isolates were ...
Yan Zhang   +8 more
doaj   +2 more sources

Ribonuclease DIS3 delays aging and senescence by generating tRNA halves [PDF]

open access: yesNature Communications
Transfer RNA (tRNA) halves (tRHs) are generated via the cleavage of tRNAs, but their roles in aging and longevity remain poorly understood. Here, we demonstrate a direct role of tRHs in aging in metazoans.
Seokjun G. Ha   +19 more
doaj   +2 more sources

Thyrotropin-releasing hormone neurons of different hypothalamic nuclei increase energy expenditure [PDF]

open access: yesNature Communications
Several neuronal populations in the hypothalamus and brainstem express thyrotropin-releasing hormone (TRH). While TRH neurons in the paraventricular nucleus (PVN) regulate the thyroid axis, the roles of other TRH-producing neurons remain largely unknown.
Andreea Constantinescu   +18 more
doaj   +2 more sources

Role of the thyrotropin-releasing hormone of the limbic system in mood and eating regulation

open access: yesJournal of Integrative Neuroscience, 2022
Thyrotropin-releasing hormone (TRH) and its receptors are expressed in the hypothalamus and limbic regions. Brain thyrotropin-releasing hormone actions are exerted directly through its receptors and indirectly by modulating the effects of ...
Elena Alvarez-Salas   +3 more
doaj   +1 more source

Biochemical and physiological insights into TRH receptor-mediated signaling

open access: yesFrontiers in Cell and Developmental Biology, 2022
Thyrotropin-releasing hormone (TRH) is an important endocrine agent that regulates the function of cells in the anterior pituitary and the central and peripheral nervous systems.
Radka Trubacova   +2 more
doaj   +1 more source

Visual Reinforcement Audiometry (VRA): examination method of hearing in the youngest children

open access: yesListy klinicke logopedie, 2020
What does a child actually hear? At what intensities and at what frequencies? The answers to these questions are extremely difficult, because a child is not able to describe his/her auditory perception to us, as an adult would.
Petra Šestáková, Radan Havlík
doaj   +1 more source

The Thyrotropin-Releasing Hormone-Degrading Ectoenzyme, a Therapeutic Target?

open access: yesFrontiers in Pharmacology, 2020
Thyrotropin releasing hormone (TRH: Glp-His-Pro-NH2) is a peptide mainly produced by brain neurons. In mammals, hypophysiotropic TRH neurons of the paraventricular nucleus of the hypothalamus integrate metabolic information and drive the secretion of ...
Jean-Louis Charli   +6 more
doaj   +1 more source

Cardiac Arrest Developing Linked to Hydatid Cyst Rupture During Operation of a Pediatric Patient

open access: yesJournal of Behçet Uz Children's Hospital, 2019
Hydatid cysts are parasitic infections created by echinococcus granulosus and echinococcus alveolaris. These infections are characterized by cyst formation with cysts most commonly localized in the liver and lungs. With rupture of the cyst due to trauma,
Bedih Balkan   +6 more
doaj   +1 more source

NR4A1 (Nur77) mediates thyrotropin-releasing hormone-induced stimulation of transcription of the thyrotropin β gene: analysis of TRH knockout mice. [PDF]

open access: yesPLoS ONE, 2012
Thyrotropin-releasing hormone (TRH) is a major stimulator of thyrotropin-stimulating hormone (TSH) synthesis in the anterior pituitary, though precisely how TRH stimulates the TSHβ gene remains unclear. Analysis of TRH-deficient mice differing in thyroid
Yasuyo Nakajima   +11 more
doaj   +1 more source

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