Transcriptional profiling of fetal hypothalamic TRH neurons [PDF]
, 2011 BackgroundDuring murine hypothalamic development, different neuroendocrine cell phenotypes are generated in overlapping periods; this suggests that cell-type specific developmental programs operate to achieve complete maturation.
Guerra-Crespo, Magdalena +15 more
core +13 more sources
Early postnatal development of thyrotropin-releasing hormone (TRH) expression, TRH receptor binding, and TRH responses in neurons of rat brainstem [PDF]
, 1994 We investigated the postnatal development of the thyrotropin-releasing hormone (TRH)-containing raphe system in the brainstem of neonatal rats. Postnatal changes in TRH expression in nucleus (n.) raphe obscurus (ROb) and n.
Berger, Albert J. +5 more
core +2 more sources
TRH: Pathophysiologic and clinical implications [PDF]
, 1985 Thyrotropin releasing hormone is thought to be a tonic stimulator of the pituitary TSH secretion regulating the setpoint of the thyrotrophs to the suppressive effect of thyroid hormones. The peptide stimulates the release of normal and elevated prolactin.
Pickardt, C. R., Scriba, Peter Christian
core +1 more source
Thyrotropin-releasing hormone (TRH) promotes wound re-epithelialisation in frog and human skin [PDF]
, 2013 There remains a critical need for new therapeutics that promote wound healing in patients suffering from chronic skin wounds. This is, in part, due to a shortage of simple, physiologically and clinically relevant test systems for investigating candidate ...
Paredes Roberto +59 more
core +2 more sources
Involvement of the hypothalamic-pituitary-thyroid axis and its interaction with the hypothalamic-pituitary-adrenal axis in the ontogeny of avian thermoregulation: a review [PDF]
, 2008 The emergence of thermoregulation in avian species is a complex matter in which neural as well as hormonal processes are involved. In a previous paper, the neural aspects of primary avian thermoregulation were discussed.
Brand, H., van den +5 more
core +1 more source
Endocrine and Metabolic Science, 2022 Background: Obesity, type 2 diabetes, and major depression are common comorbidities in aging populations. Metformin (MF) mimics effects of caloric restriction (CR) which increases health and life spans.
Albert Eugene Pekary, Albert Sattin
doaj +1 more source
Development of TRH and TRH degrading activity(TRH-DA) in the hypothalamus and plasma of rats. [PDF]
Pediatric Research, 1979 Development of TRH and TRH degrading activity(TRH-DA) in the hypothalamus and plasma of rats.
S Aratan-Spire, R Pomarede, P Czernichow
openaire +1 more source
Type 1 cannabinoid receptor-containing axons innervate hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons. [PDF]
, 2009 Hypophysiotropic TRH-synthesizing neurons of the hypothalamic paraventricular nucleus (PVN) have a critical role in the regulation of the energy homeostasis through control of the hypothalamic-pituitary-thyroid axis.
Wittmann, Gábor +6 more
core +1 more source
Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor
Frontiers in Endocrinology, 2012 Taltirelin (TAL) is a thyrotropin-releasing hormone (TRH) analog that is approved for use in humans in Japan. In this study, we characterized TAL binding to and signaling by the human TRH receptor (TRH-R) in a model cell system.
Nanthakumar eThirunarayanan +2 more
doaj +1 more source
Folia Morphologica, 2022 BACKGROUND: In this study, the purpose was to determine the anatomical localisations of the cervical oesophagus length, hiatal clamp, and oesophagogastric junction depending on age and gender in patients who undergo oesophagogastroduodenoscopy (EGD ...
E. Bozdag +5 more
doaj +1 more source