Results 31 to 40 of about 36,954 (245)

Thyrotropin-Releasing Hormone (TRH) Analogues That Exhibit Selectivity to TRH Receptor Subtype 2

, 2016
Thyrotropin-releasing hormone (TRH) analogues in which the C-2 position of the imidazole ring of the centrally placed histidine residue is substituted with various alkyl groups were synthesized and studied as agonists for TRH receptor subtype 1 (TRH-R1 ...
Navneet Kaur (1447987), Marvin C. Gershengorn (234508), Rahul Jain (1315032), Xinping Lu (231891)   +3 more
core   +1 more source

GATA2 mediates thyrotropin-releasing hormone-induced transcriptional activation of the thyrotropin β gene. [PDF]

PLoS ONE, 2011
Thyrotropin-releasing hormone (TRH) activates not only the secretion of thyrotropin (TSH) but also the transcription of TSHβ and α-glycoprotein (αGSU) subunit genes.
Kenji Ohba, Shigekazu Sasaki, Akio Matsushita, Hiroyuki Iwaki, Hideyuki Matsunaga, Shingo Suzuki, Keiko Ishizuka, Hiroko Misawa, Yutaka Oki, Hirotoshi Nakamura   +9 more
doaj   +1 more source

Comparison of Ultrasound-Guided Quadratus Lumborum Plane Block and External Oblique Intercostal Plane Block for Postoperative Analgesia After Laparoscopic Cholecystectomy: A Two-Center Randomized Controlled Trial

Medicina
Background and Objectives: Although various regional anesthesia techniques are commonly used for laparoscopic cholecystectomy (LC), to date, no randomized controlled trial has compared the effectiveness of Quadratus Lumborum Plane Block (QLB) and ...
Cem Kıvılcım Kaçar, Andaç Dedeoğlu, Hülya Tosun Söner, Enes Çelik, Okan Andıç, Fatma Acil, Hakan Akelma, Osman Uzundere, Erhan Gökçek   +8 more
doaj   +1 more source

Occurrence of Vibrio parahaemolyticus in cockle (Anadara granosa) harvested from the south coast of Thailand [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2011
Vibrio parahaemolyticus is a seafood-borne pathogen that is widely distributed in the marine environment. Theoccurrence of Vibrio parahaemolyticus in cockle (Anadara granosa) harvested at the south coast of Thailand was determined.A total of 65 samples ...
Srimek Chowpongpang, Benchamaporn Pimpa, Duangkhae Kanjanasopa   +2 more
doaj  

Optimized Cas9‐Enriched Nanopore Sequencing and Analysis Workflow for Clinical Diagnosis of Repeat Expansion Disorders

Advanced Science, EarlyView.
An optimized Cas9‐enriched nanopore sequencing workflow, combined with STRiker, enables simultaneous analysis of disease‐associated STR loci from patient blood. The nCATS–STRiker workflow detects repeat expansions, de novo repeat motifs, interruption patterns, and methylation in a single assay, improving the genetic diagnosis of previously undiagnosed ...
Seungbok Lee, Chanju Jung, Minjeong Kim, Narae Kim, Gue‐Ho Hwang, Soon‐Tae Lee, Kon Chu, Sang Kun Lee, Han‐Joon Kim, Jong‐Hee Chae, Sangsu Bae, Jangsup Moon   +11 more
wiley   +1 more source

A Glial-Neuronal Circuit in the Median Eminence Regulates Thyrotropin-Releasing Hormone-Release via the Endocannabinoid System

iScience, 2020
Summary: Based on the type-I cannabinoid receptor (CB1) content of hypophysiotropic axons and the involvement of tanycytes in the regulation of the hypothalamic-pituitary-thyroid (HPT) axis, we hypothesized that endocannabinoids are involved in the ...
Erzsébet Farkas, Edina Varga, Balázs Kovács, Anett Szilvásy-Szabó, Antonieta Cote-Vélez, Zoltán Péterfi, Magdalini Matziari, Mónika Tóth, Dóra Zelena, Zsolt Mezriczky, Andrea Kádár, Dóra Kővári, Masahiko Watanabe, Masanobu Kano, Ken Mackie, Balázs Rózsa, Yvette Ruska, Blanka Tóth, Zoltán Máté, Ferenc Erdélyi, Gábor Szabó, Balázs Gereben, Ronald M. Lechan, Jean-Louis Charli, Patricia Joseph-Bravo, Csaba Fekete   +25 more
doaj   +1 more source

Triple-dose bolus versus continuous infusion of tranexamic acid: impacts on clinical outcomes in isolated coronary artery bypass surgery

Journal of Cardiothoracic Surgery
Background In cardiac surgery, intraoperative tranexamic acid (TXA) is commonly used and highly recommended approach for managing perioperative bleeding. Nevertheless, a standardized dose and administration protocol remains undefined. This study compares
Osman Uzundere, Mahmut Yargı, Selen Topalel, Ahmet Serkan Aydın, Meral Erdal Erbatur, Hülya Tosun Söner, Reşit Saruhan, Cem Kıvılcım Kaçar, Erhan Gökçek   +8 more
doaj   +1 more source

Contribution of Thyrotropin-Releasing Hormone to Cerebellar Long-Term Depression and Motor Learning

Frontiers in Cellular Neuroscience, 2018
Thyrotropin-releasing hormone (TRH) regulates various physiological activities through activation of receptors expressed in a broad range of cells in the central nervous system.
Masashi Watanave, Yasunori Matsuzaki, Yasuyo Nakajima, Atsushi Ozawa, Masanobu Yamada, Hirokazu Hirai, Hirokazu Hirai   +6 more
doaj   +1 more source

Longitudinal Study of Total and Pathogenic Vibrio parahaemolyticus (tdh+ and/or trh+) in Two Natural Extraction Areas of Mytilus chilensis in Southern Chile

Frontiers in Microbiology, 2021
Vibrio parahaemolyticus is the leading cause of seafood-associated bacterial gastroenteritis worldwide. Although different studies have focused on its pattern of variation over time, knowledge about the environmental factors driving the dynamics of this ...
Cristina Bacian, Cristina Bacian, Cristobal Verdugo, Katherine García, Josu Perez-Larruscain, Ignacio de Blas, Viviana Cachicas, Carmen Lopez-Joven   +7 more
doaj   +1 more source

Transfer RNA‐Derived Small RNA‐5’tiRNAGln Drives HNRNPC Phase Separation to Promote Breast Cancer Bone Metastasis by Regulating IGF1R

Advanced Science, EarlyView.
This study reveals that 5'tiRNA‐Gln interacts with hnRNPC to promote IGF1R liquid‐liquid phase separation, which drives ERK1/2 signaling activation, EMT, and breast cancer bone metastasis. These findings highlight a novel mechanism of breast cancer bone metastasis and potential therapeutic target in metastatic breast cancer.
Bingnan Wang, Dongsong Liu, Xiaozhi Fan, Jiale Fan, Xuesi liu, Yu Wang, Zixin Wang, Mo Cheng, Ping Zhou, Wangjun Yan   +9 more
wiley   +1 more source