Results 51 to 60 of about 25,893 (220)

Cloning and heterologous expression of bovine pyroglutamyl peptidase type-1 in Escherichia coli : purification , biochemical and kinetic characterisation [PDF]

, 2007
We describe the cloning, expression and purification of the bovine XM866409 form of pyroglutamyl-aminopeptidase I. The amino acid sequence, deduced from the nucleotide sequence, revealed that it consists of 209 amino acid residues and showed to have 98 ...
O'Connor, Brendan, Ó Cuív, Páraic, O\u27Connor, Brendan, Vaas, Paul-Roman, Ó Cuiv, Padraig, Kilbane, Zelda   +5 more
core   +1 more source

A Novel Antioxidant Peptide Cath‐Np Derived from Nanorana parkeri Attenuates UVB‐Induced Skin Photodamage in Mice

Integrative Zoology, EarlyView.
Schematic representation of Cath‐Np as an antioxidant suppressing acute skin damage caused by ultraviolet B (UVB) radiation in mice. Cath‐Np inhibits the activation of p53 and mitogen‐activated protein kinase pathways while it activates the Nrf2 pathway by its strong antioxidant effects, and accordingly suppresses the expression of inflammatory factors
Hang Liao, Xiaoxiao Shen, Jinwei Chai, Kai wang, Jiena Wu, Jianxi Yang, Ming Chen, Guoxiang Mo, Xueqing Xu   +8 more
wiley   +1 more source

A hipotalamusz paraventrikuláris magjában (PVN) elhelyezkedő tirotropin-releasing hormont (TRH) termelő idegsejtek TRH általi szabályozásának és a tanicitákkal létesített kapcsolatának elektrofiziológiai karakterizálása [PDF]

, 2022
The function of the hypophysiotropic TRH neurons of the PVN is essential in the regulation of the hypothalamic-pituitary-thyroid (HPT) axis and through this effect, these neurons are also crucial in the regulation of energy homeostasis, therefore ...
Kovács Balázs
core  

Trajectories of medication for opioid use disorder and their impact on HIV testing among people who inject drugs in India: A longitudinal assessment of clinic‐based data

Addiction, Volume 120, Issue 4, Page 745-755, April 2025.
Abstract Aims The aim of this study was to identify longitudinal trajectories of medication for opioid use disorder (MOUD) use throughout 1 year following MOUD initiation and to examine the association of trajectory membership with HIV testing among people who inject drugs in India.
Allison M. McFall, Lakshmi Ganapathi, Mihili P. Gunaratne, Aylur K. Srikrishnan, Conjeevaram K. Vasudevan, Santhanam Anand, Sunil S. Solomon, Shruti H. Mehta, Gregory M. Lucas   +8 more
wiley   +1 more source

Effect of TRH-T in an experimental model of haemorrhagic shock.

, 1988
In experimental models of endotoxic, haemorrhagic, anaphylactic and spinal shock, TRH improves blood pressure and short-term ...
GUARINI, Salvatore, BERTOLINI, Alfio, Tagliavini S.   +2 more
core  

Microarray and K-means cluster analyses of genes regulated by TRH and by thyroid hormone in TRH-deficient pituitary.

, 2013
RNA samples from pituitaries of wild-type, TRHKO (TRH−/−), and euthyroid TRHKO mice with thryroid hormone replacement (TRH−/−+T4) were subjected to a whole-genome microarray using Affymetrix Mouse Gene chip 320 2.0 Array.
Takafumi Tsuchiya (312870), Masanobu Yamada (287163), Tsugumichi Saito (312859), Ryo Taguchi (142271), Koshi Hashimoto (287160), Takuya Tomaru (316586), Nobuyuki Shibusawa (316582), Atsushi Ozawa (316584), Yasuyo Nakajima (316579), Tetsurou Satoh (287162), Shuichi Okada (287161), Masatomo Mori (65179)   +11 more
core   +1 more source

Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report

Allergy, EarlyView.
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter, Ioana Agache, Beatriz Cabanillas, Roberto Berni Canani, Pasquale Comberiati, Holger Garn, Cristina Gomez‐Casado, Karin Hufnagl, Ekaterina Khaleva, Gregorio P. Milani, Daniel Munblit, Nikolaos Douladiris, Liam O'Mahony, Frank Redegeld, Carmen Riggioni, Peter K. Smith, Betty van Esch, Emilia Vassilopoulou, Carina Venter, Diego G. Peroni   +19 more
wiley   +1 more source

A Specific tRNA Half, 3'tiRNA‐GlyGCC, Regulates Hypoxic Pulmonary Artery Smooth Muscle Cell Proliferation via Myrf‐Mediated Endoplasmic Reticulum Stress

Cell Proliferation, EarlyView.
A schematic diagram illustrating how 3′tiRNA‐GlyGCC promotes the endoplasmic reticulum stress (ERS) and proliferation in hypoxic pulmonary artery smooth muscle cells (PASMCs) by inhibiting the expression of myelin regulatory factor (Myrf), ultimately leading to pulmonary hypertension (PH).
Lixin Zhang, Xiaoyu Guan, Xiangrui Zhu, Yingying Hao, Ya Xu, Hao Yuan, Danni Gao, Hongxia Du, Jiayu Li, Weiwei Cao, Cui Ma, Xiaoying Wang   +11 more
wiley   +1 more source

Thyroliberin (TRH) and TRH free acid (TRH-OH) present in milk do not originate from local synthesis in mammary gland.

, 1991
International audienceHypothalamic hormones represent a peculiar group of hormones present in milk in surprisingly high concentrations. High levels of these neuropeptides raised the question of their origin.
Ouafik, L, Oliver, C., Resetková, E, Randuskovà, A, Povazanová, K, Dutour, A., Giraud, P., Strbák, A   +7 more
core  

Effect of low intravenous doses of TRH, acid-TRH and cyclo(His-Pro) on cerebral and peripheral blood flows

, 1986
Local cerebral and peripheral blood flow in conscious and anaesthetized rabbits were investigated with the microsphere method, before and after the i.v. administration of 25 or 50 micrograms kg-1 thyrotropin-releasing hormone (TRH). Before the experiment,
Koskinen, Lars-Owe D.,
core   +1 more source