Results 51 to 60 of about 23,921 (208)

Roles of thermostable direct hemolysin (TDH) and TDH-related hemolysin (TRH) in Vibrio parahaemolyticus

open access: yesFrontiers in Microbiology, 2015
Vibrio parahaemolyticus is the leading cause of seafood borne bacterial gastroenteritis in the world, often associated with the consumption of raw or undercooked seafood. However, not all strains of V. parahaemolyticus are pathogenic.
Pendru eRaghunath
doaj   +1 more source

Interaction between the hypothalamo-pituitary-adrenal and thyroid axes during immobilization stress

open access: yesFrontiers in Physiology, 2022
The location of corticotropin-releasing hormone receptor 2 (CRH-R2) on thyrotropes within the avian anterior pituitary (APit) and its activation by different stressors indicate a possible communication between hypothalamo-pituitary-adrenal (HPA) and ...
Hakeem J. Kadhim, Wayne J. Kuenzel
doaj   +1 more source

Thyrotropin-Releasing Hormone (TRH) Analogues That Exhibit Selectivity to TRH Receptor Subtype 2

open access: yes, 2016
Thyrotropin-releasing hormone (TRH) analogues in which the C-2 position of the imidazole ring of the centrally placed histidine residue is substituted with various alkyl groups were synthesized and studied as agonists for TRH receptor subtype 1 (TRH-R1 ...
Navneet Kaur (1447987)   +3 more
core   +1 more source

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Fitness and transcriptomic analysis of pathogenic Vibrio parahaemolyticus in seawater at different shellfish harvesting temperatures

open access: yesMicrobiology Spectrum, 2023
To better characterize the population dynamics of Vibrio parahaemolyticus (Vp) containing different virulence genes, two Vp strains were inoculated into seawater separately and incubated at temperatures (10°C and 30°C) mimicking winter and summer pre ...
Zhuosheng Liu, Chao Liao, Luxin Wang
doaj   +1 more source

Cloning and heterologous expression of bovine pyroglutamyl peptidase type-1 in Escherichia coli : purification , biochemical and kinetic characterisation [PDF]

open access: yes, 2007
We describe the cloning, expression and purification of the bovine XM866409 form of pyroglutamyl-aminopeptidase I. The amino acid sequence, deduced from the nucleotide sequence, revealed that it consists of 209 amino acid residues and showed to have 98 ...
O'Connor, Brendan   +5 more
core   +2 more sources

Sleep in Young Children With Autism, ADHD and Combined Presentations

open access: yesAutism Research, EarlyView.
ABSTRACT Autism and attention deficit hyperactivity disorder (ADHD) are often accompanied by sleep problems. Longitudinal studies hint towards a greater proportion of persisting sleep problems across early development in neurodivergent compared to neurotypical individuals. Within the context of a prospective infant sibling study of autism and ADHD (n = 
Eva‐Maria Kurz   +2 more
wiley   +1 more source

Thyrotropin-Releasing Hormone and Food Intake in Mammals: An Update

open access: yesMetabolites
Thyrotropin-releasing hormone (TRH; pGlu-His-Pro-NH2) is an intercellular signal produced mainly by neurons. Among the multiple pharmacological effects of TRH, that on food intake is not well understood.
Yamili Vargas   +5 more
doaj   +1 more source

Harnessing ferroptosis from multilayer defense networks to nanoplatforms for specific cancer therapy

open access: yesBMEMat, EarlyView.
Nanomaterials target metabolically‐regulated ferroptosis for cancer therapy. Iron‐based or alternative nanoplatforms integrate ferroptosis with chemotherapy, immunotherapy, or radiotherapy. They enable stimulus‐responsive therapies (photothermal, photodynamic, sonodynamic) activated by near‐infrared, light, or ultrasound, achieving potent synergistic ...
Xinyue Xu   +5 more
wiley   +1 more source

Achieving Carbon Neutrality: Strategic Pathways to Sustainability and Net Zero in Manufacturing Supply Chains

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Reaching global net‐zero targets has become an urgent priority as businesses and nations face increasing pressure to reduce greenhouse gas emissions. Achieving carbon neutrality in manufacturing supply chains requires comprehensive systemic changes across business processes.
Vimal K. E. K.   +5 more
wiley   +1 more source

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