Results 61 to 70 of about 12,599 (218)

Ribonuclease DIS3 delays aging and senescence by generating tRNA halves

Nature Communications
Transfer RNA (tRNA) halves (tRHs) are generated via the cleavage of tRNAs, but their roles in aging and longevity remain poorly understood. Here, we demonstrate a direct role of tRHs in aging in metazoans.
Seokjun G. Ha, Hanseul Lee, Jisoo Park, Donghun Lee, Gee-Yoon Lee, Seokjin Ham, Sujeong Kwon, Sangsoon Park, Sieun S. Kim, Yoonji Jung, Jongsun Lee, Jooyeon Sohn, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Hyeong-In Kim, Eunseok Kang, Yoon Ki Kim, Gwangrog Lee, Seung-Jae V. Lee   +19 more
doaj   +1 more source

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy

Epilepsia, EarlyView.
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger, Xinbing Zhang, Thomas Lisko, Hafsa Farooqi, Steffen Ventz, Sandipan Pati, Thomas R. Henry, David P. Darrow, Michael C. Park, Theoden I. Netoff, Robert A. McGovern   +10 more
wiley   +1 more source

TRH-Like Peptides

Physiological Research, 2011
TRH-like peptides are characterized by substitution of basic amino acid histidine (related to authentic TRH) with neutral or acidic amino acid, like glutamic acid, phenylalanine, glutamine, tyrosine, leucin, valin, aspartic acid and asparagine.
R, Bílek, M, Bičíková, L, Šafařík
openaire   +2 more sources

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

Food Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi, Naomi A. Mogborukor, Baridoo Donatus Dooka, Polycarp Dauda Madaki, Chiara Frazzoli, Mohamed Haddad, Orish Ebere Orisakwe   +6 more
wiley   +1 more source

Prevalence and risk factors for postpartum depression and stress among mothers of preterm and low birthweight infants admitted to a neonatal intensive care unit in Accra, Ghana

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 131-137, April 2025.
Abstract To determine the prevalence of postpartum depression (PPD) and postpartum stress (PPS) and identify associated risk factors among mothers of preterm and low birth weight (LBW) infants. We conducted a secondary analysis of data collected from 255 mothers with preterm and LBW infants admitted to the neonatal intensive care unit (NICU) at Korle ...
John Pellegrino, Paddington T. Mundagowa, Kwame Sarfo Sakyi, Prince Gyebi Owusu, Babbel Agbinko‐Djobalar, Leila M. Larson, Mufaro Kanyangarara   +6 more
wiley   +1 more source

Genetic and Adverse Health Outcome Associations with Treatment Resistant Hypertension in GenHAT

International Journal of Hypertension, 2013
Treatment resistant hypertension (TRH) is defined as uncontrolled hypertension (HTN) despite the use of ≥3 antihypertensive medication classes or controlled HTN while treated with ≥4 antihypertensive medication classes.
Amy I. Lynch, Marguerite R. Irvin, Barry R. Davis, Charles E. Ford, John H. Eckfeldt, Donna K. Arnett   +5 more
doaj   +1 more source

The Impact of School‐Based Group Adlerian Play Therapy on Internalizing Behaviors

Journal of Counseling &Development, EarlyView.
ABSTRACT This study examined the impact of group Adlerian play therapy (GAdPT) compared to a waitlist control group (WG) with 94 fourth‐ and fifth‐grade students reporting clinical levels of internalizing behaviors. Forty‐eight students were assigned to GAdPT and 46 were assigned to the WG.
Kelly A. Owen, Jolie Ziomek‐Daigle, C. Missy Moore, Brandee Appling   +3 more
wiley   +1 more source

Characterization of a novel thyrotropin-releasing hormone receptor, TRHR3, in chickens

Poultry Science, 2020
The physiological roles of thyrotropin-releasing hormone (TRH) are proposed to be mediated by TRH receptors (TRHR), which have been divided into 3 subtypes, namely, TRHR1, TRHR2, and TRHR3, in vertebrates.
Xiaoxiao Li, Zhengyang Li, Yue Deng, Jiannan Zhang, Juan Li, Yajun Wang   +5 more
doaj   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source

The Impact of the Choice of Evaluation Criteria and the Type of Tender on the Awarding Public Contracts (in the Case of Construction Contracts at the Local Level in the Czech Republic)

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
Public procurement may be examined from different perspectives. Using the Czech Republic as an example, this study is devoted to examining the impact of decisions made by the contracting authority regarding a public tender on the tender process itself ...
František Ochrana, Kristýna Hrnčířová, Michal Plaček, Milan Půček   +3 more
doaj   +1 more source