Results 71 to 80 of about 23,921 (208)

Ribonuclease DIS3 delays aging and senescence by generating tRNA halves

Nature Communications
Transfer RNA (tRNA) halves (tRHs) are generated via the cleavage of tRNAs, but their roles in aging and longevity remain poorly understood. Here, we demonstrate a direct role of tRHs in aging in metazoans.
Seokjun G. Ha, Hanseul Lee, Jisoo Park, Donghun Lee, Gee-Yoon Lee, Seokjin Ham, Sujeong Kwon, Sangsoon Park, Sieun S. Kim, Yoonji Jung, Jongsun Lee, Jooyeon Sohn, Seon Woo A. An, Heehwa G. Son, Wooseon Hwang, Hyeong-In Kim, Eunseok Kang, Yoon Ki Kim, Gwangrog Lee, Seung-Jae V. Lee   +19 more
doaj   +1 more source

Evaluation of a new immunoassay for measuring equine serum insulin and plasma adrenocorticotrophic hormone: A method comparison study

Equine Veterinary Journal, EarlyView.
Abstract Background Insulin dysregulation (ID) and pituitary pars intermedia dysfunction (PPID) are common equine endocrinopathies detected by measurement of circulating insulin and adrenocorticotrophic hormone (ACTH) concentrations. Different assays may yield variable results, limiting comparability.
Nicola J. Menzies‐Gow, Perrine Cosin, Valerie Guyot   +2 more
wiley   +1 more source

TRH-Like Peptides

Physiological Research, 2011
TRH-like peptides are characterized by substitution of basic amino acid histidine (related to authentic TRH) with neutral or acidic amino acid, like glutamic acid, phenylalanine, glutamine, tyrosine, leucin, valin, aspartic acid and asparagine.
R, Bílek, M, Bičíková, L, Šafařík
openaire   +2 more sources

Food Contamination and Safety in Nigeria: A Systematic Synthesis of Heavy Metals, Microbial Pathogens, and Health Risk Metrics

Food Safety and Health, EarlyView.
This is an infographic driver of food contaminants and health effects. ABSTRACT Food safety remains a critical challenge in Nigeria due to rapid urbanization and weak regulatory enforcement. This systematic review synthesizes empirical evidence from 2015 to 2025 to characterize food contaminant profiles and associated human health risks in Nigeria ...
Cecilia Nwadiuto Obasi, Naomi A. Mogborukor, Baridoo Donatus Dooka, Polycarp Dauda Madaki, Chiara Frazzoli, Mohamed Haddad, Orish Ebere Orisakwe   +6 more
wiley   +1 more source

Thyroliberin (TRH) and TRH free acid (TRH-OH) present in milk do not originate from local synthesis in mammary gland.

, 1991
International audienceHypothalamic hormones represent a peculiar group of hormones present in milk in surprisingly high concentrations. High levels of these neuropeptides raised the question of their origin.
Ouafik, L, Oliver, C., Resetková, E, Randuskovà, A, Povazanová, K, Dutour, A., Giraud, P., Strbák, A   +7 more
core   +1 more source

Intracisternal antisense oligonucleotides to TRH receptor abolish TRH-evoked gastric motor excitation

, 1997
Thyrotropin-releasing hormone (TRH) from the nucleus raphe obscurus (nROb) innervates the dorsal vagal complex (DVC) and activates gastric motor function. Assessment of the importance of TRH has been hampered by the lack of TRH receptor antagonists.
D. V. Sivarao, T. P. Abrahams, Z. K. Krowicki, P. J. Hornby   +3 more
core   +1 more source

Prevalence and risk factors for postpartum depression and stress among mothers of preterm and low birthweight infants admitted to a neonatal intensive care unit in Accra, Ghana

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 131-137, April 2025.
Abstract To determine the prevalence of postpartum depression (PPD) and postpartum stress (PPS) and identify associated risk factors among mothers of preterm and low birth weight (LBW) infants. We conducted a secondary analysis of data collected from 255 mothers with preterm and LBW infants admitted to the neonatal intensive care unit (NICU) at Korle ...
John Pellegrino, Paddington T. Mundagowa, Kwame Sarfo Sakyi, Prince Gyebi Owusu, Babbel Agbinko‐Djobalar, Leila M. Larson, Mufaro Kanyangarara   +6 more
wiley   +1 more source

Genetic and Adverse Health Outcome Associations with Treatment Resistant Hypertension in GenHAT

International Journal of Hypertension, 2013
Treatment resistant hypertension (TRH) is defined as uncontrolled hypertension (HTN) despite the use of ≥3 antihypertensive medication classes or controlled HTN while treated with ≥4 antihypertensive medication classes.
Amy I. Lynch, Marguerite R. Irvin, Barry R. Davis, Charles E. Ford, John H. Eckfeldt, Donna K. Arnett   +5 more
doaj   +1 more source

The Impact of the Choice of Evaluation Criteria and the Type of Tender on the Awarding Public Contracts (in the Case of Construction Contracts at the Local Level in the Czech Republic)

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
Public procurement may be examined from different perspectives. Using the Czech Republic as an example, this study is devoted to examining the impact of decisions made by the contracting authority regarding a public tender on the tender process itself ...
František Ochrana, Kristýna Hrnčířová, Michal Plaček, Milan Půček   +3 more
doaj   +1 more source

Neurotensin-induced antinociception and hypothermia in mice: antagonism by TRH and structural analogs of TRH

, 1984
Intracisternal (IC) administration of neurotensin (NT) in a dose of 10 μg produced a significant hypothermia and antinociception in the hot-plate test in mice.
Hernandez, Daniel E, Prange, Arthur J, Nemeroff, Charles B, Valderrama, Miguel H   +3 more
core   +1 more source