Results 71 to 80 of about 36,954 (245)

Rifaximin modulates TRH and TRH-like peptide expression throughout the brain and peripheral tissues of male rats

BMC Neuroscience, 2022
Background The TRH/TRH-R1 receptor signaling pathway within the neurons of the dorsal vagal complex is an important mediator of the brain-gut axis.
Albert Eugene Pekary, Albert Sattin
doaj   +1 more source

Precision Fermentation for Next Generation Food Ingredients: Technological Foundations, Food Applications, Sustainability, and Regulatory Challenges

Food Bioengineering, EarlyView.
Precision fermentation uses engineered microorganisms to produce targeted food ingredients, including proteins, enzymes, lipids, flavors, vitamins, and bioactives. This review examines its technological foundations, food applications, safety, sustainability, economics, regulation, and consumer acceptance, emphasizing that performance depends on host ...
Nora Ali Hassan, Rawaa H. Tlay, Tarek Gamal Abedelmaksoud   +2 more
wiley   +1 more source

Hypothalamic Median Eminence Thyrotropin-Releasing Hormone-Degrading Ectoenzyme Activity Is Dispensable for Basal Thyroid Axis Activity in Lean Rodents

Cells
The amplitude of the phasic output of thyrotropin-releasing hormone (TRH) into the hypothalamus–pituitary portal capillaries is likely controlled by the TRH-degrading ectoenzyme (TRH-DE) expressed on the surface of median eminence (ME) β2-tanycytes.
Adair Rodríguez-Rodríguez, Rosa María Uribe, Antonieta Cote-Vélez, Patricia Joseph-Bravo, Jean-Louis Charli   +4 more
doaj   +1 more source

Pituitary Thyrotropin-Releasing Hormone (TRH) Receptors: Effects of TRH, Drugs Mimicking TRH Action, and Chlordiazepoxide [PDF]

Molecular Endocrinology, 1989
Binding of TRH to specific cell surface receptors on clonal GH4C1 cells is followed within 10 min by receptor sequestration and over 24 h by receptor down-regulation. These experiments were designed to determine if TRH-activated second messenger systems are responsible for changes in receptor localization or number. BAY K8644 and A23187, which increase
P M, Hinkle, E D, Shanshala
openaire   +2 more sources

Prevalence and risk factors for postpartum depression and stress among mothers of preterm and low birthweight infants admitted to a neonatal intensive care unit in Accra, Ghana

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 131-137, April 2025.
Abstract To determine the prevalence of postpartum depression (PPD) and postpartum stress (PPS) and identify associated risk factors among mothers of preterm and low birth weight (LBW) infants. We conducted a secondary analysis of data collected from 255 mothers with preterm and LBW infants admitted to the neonatal intensive care unit (NICU) at Korle ...
John Pellegrino, Paddington T. Mundagowa, Kwame Sarfo Sakyi, Prince Gyebi Owusu, Babbel Agbinko‐Djobalar, Leila M. Larson, Mufaro Kanyangarara   +6 more
wiley   +1 more source

Bidirectional Pathological Axis Between Alzheimer's Disease and Circadian Rhythm Disturbance: Mechanisms and Therapeutic Strategies

iNew Medicine, EarlyView.
This graphical abstract illustrates a bidirectional vicious cycle between Alzheimer’s disease (AD) and circadian rhythm disturbance (CRD). On the one hand, AD pathology, including amyloid‐β (Aβ) plaque deposition and tau hyperphosphorylation, may damage the suprachiasmatic nucleus (SCN) and disrupt melatonin signaling, leading to sleep fragmentation ...
Jiajia Qin, Xianfeng Yu, Yayu Wang, Xiaohan Song, Yuehua Wang, Zhixin Wang, Wei Miao, Xudong Yang, Jiajia Zhu, Xiaoqun Zhu, Maria‐Trinidad Herrero   +10 more
wiley   +1 more source

The Impact of the Choice of Evaluation Criteria and the Type of Tender on the Awarding Public Contracts (in the Case of Construction Contracts at the Local Level in the Czech Republic)

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2015
Public procurement may be examined from different perspectives. Using the Czech Republic as an example, this study is devoted to examining the impact of decisions made by the contracting authority regarding a public tender on the tender process itself ...
František Ochrana, Kristýna Hrnčířová, Michal Plaček, Milan Půček   +3 more
doaj   +1 more source

TRH-Like Peptides

Physiological Research, 2011
TRH-like peptides are characterized by substitution of basic amino acid histidine (related to authentic TRH) with neutral or acidic amino acid, like glutamic acid, phenylalanine, glutamine, tyrosine, leucin, valin, aspartic acid and asparagine.
R, Bílek, M, Bičíková, L, Šafařík
openaire   +2 more sources

Phenotypic and Genotypic Analysis of Two Rare Cases of ‐‐SEA/‐α4.3 HbH Disease

Journal of Clinical Laboratory Analysis, EarlyView.
We report two unrelated adult patients with rare deletional HbH disease (genotype ‐‐SEA/‐α4.3). This novel 4.3 kb deletion covering the HBA1 gene is accompanied by X‐Y‐Z segment recombination, which was identified by CycloneSEQ long‐read nanopore sequencing.
Weijia Yang, Xiaoyan Huang, Li Zhang, Xiaoqin Yang, Yaya Guo, Qingping Kang, Min Dou, Guijun Huang   +7 more
wiley   +1 more source

Optimizing IMPULSED Acquisition Protocols for Clinical 3T Scanners Through Bayesian Experimental Design

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To optimize diffusion MRI acquisition protocols for Imaging Microstructural Parameters Using Limited Spectrally Edited Diffusion (IMPULSED) model at clinical 3T scanner using Bayesian experimental design, enabling accurate cellular‐scale parameter estimation under realistic scan time and scanner hardware constraints.
Yan Dai, Xun Jia, Todd Aguilera, Kai Jiang, Arely Perez Rodriguez, Isabelle Vanhaezebrouck, Jie Deng   +6 more
wiley   +1 more source